Some interesting Bupleurum (Apiaceae) specimens with very branched stems, (1–)2-rayed inflorescences and ivory-white bracteoles were collected from Tepebaşı District (Eskişehir Province). The specimes, at first glance, resembled the Bupleurum pendikum (sect. Aristata) species, which is endemic in Türkiye, as a habit. However, as a result of detailed examination, it was determined that there were some differences. Based on these differences, the specimens were presented to the scientific world as a new variety and were named Bupleurum pendikum var. eskisehiricum. The fact that the inflorescences are (1–)2 rays (not (2–)34(–5)); the bracteoles are 2.6–3.7 mm broad, ovate-elliptic and with arista up to 0.5 mm long (not 1.2–2 mm broad, lanceolate and with arista 11.5 mm long); the petals 0.6–0.8 mm broad (not 0.4–0.5 mm broad); the filaments 0.7–0.8 mm long (not c. 0.5 mm long) and the mericarps 2.7–3.1 × 1.1–1.3 mm (not 2.2–2.4 × 0.9–1 mm) are the most obvious attributes that separate Bupleurum pendikum var. eskisehiricum from B. pendikum (var. pendikum), that is a close taxon. Here, a detailed description of the new variety, informative photographs, and some ecological preferences were given.