Yıl: 2022 Cilt: 27 Sayı: 4 Sayfa Aralığı: 596 - 600 Metin Dili: İngilizce DOI: 10.5505/ejm.2022.03780 İndeks Tarihi: 26-05-2023

Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital

Öz:
To investigate the cases of pulmonary thromboembolism (PTE) and to analyze the risk factors in patients undergoing gynecologic oncology operations. Material and methods: The medical records of all patients who underwent gynecologic oncology surgery from January 2015 to September 2022 were collected from the hospital’s database. Cases with the diagnosis of PTE were retrieved and analyzed retrospectively. Nine cases of clinically apparent PTE were identified in the medical records. The mean age of the patients was 56.1 3.4. The mean BMI was 27.21.4. The majority of the cases were advanced stage ovarian malignancy who underwent a major surgery including pelvic-paraaortic lymphadenectomy (5/9). Dyspnea and shortness of breath was the main complaint. Tachypnea was the main finding in all cases. The leukocytosis and the thrombocytosis were notable in PTE cases. PTE remains as one of the fatal complications after gynecologic surgeries. In our case-cohort, increasing age, obesity and the complexity of surgery are significant predictors of pulmonary embolism in gynecologic oncology operations. Further multicenter studies stratifying risk factors are warranted to reach a proper prophylactic strategy and prevent PTE.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Heit JA, Mohr DN, Silverstein MD, Petterson TM, O’Fallon WM, Melton LJ 3rd. Predictors of recurrence after deep venous thrombosis and pulmonary embolism: a population- based cohort study. Arch Intern Med 2000;160:761–8.
  • 2. Clarke-Pearson DL, Synan IS, Coleman RE, Hinshaw W, Creasman WT. The natural history of postoperative venous thromboemboli in gynecologic oncology: a prospective study of 382 patients. Am J Obstet Gynecol 1984;148:1051–4.
  • 3. Middeldorp S, Meinardi JR, Koopman MM, et al. A prospective study of asymptomatic carriers of the factor V Leiden mutation to determine the incidence of venous thromboem- bolism. Ann Intern Med 2001;135:322–7.
  • 4. Rosendaal FR. Venous thrombosis: a multicausal disease. Lancet. 1999;353:1167Y1173.
  • 5. Srivastava SD, Eagleton MJ, Greenfield LJ. Diagnosis of pulmo- nary embolism with various imaging modalities. Semin Vasc Surg 2004 (Jun);17(2):173 – 80.
  • 6. Davis JD. Prevention, diagnosis and treatment of venous thromboembolic complications of gynecologic surgery. Am J Obstet Gynecol 2001;184:759 – 75.
  • 7. American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins— Gynecology. Prevention of Venous Thromboembolism in Gynecologic Surgery: ACOG Practice Bulletin, Number 232. Obstet Gynecol. 2021 Jul 1;138(1):e1-e15.
  • 8. Cronin M, Dengler N, Krauss ES, et al. Completion of the updated Caprini Risk Assessment Model (2013 version). Clin Appl Thromb Hemost 2019;25:3.
  • 9. Feng JP, Xiong YT, Fan ZQ, Yan LJ, Wang JY, Gu ZJ. Efficacy of intermittent pneumatic compression for venous thromboembolism prophylaxis in patients undergoing gynecologic surgery: a systematic review and meta-analy- sis. Oncotarget 2017;8:20371–9.
  • 10. Pistolesi M, Miniati M. Imaging techniques in treatment algorithms of pulmonary embolism. Eur Respir J 2002;19(35):28 – 39.
  • 11. Olin JW. Pulmonary Embolism. Rev Cardiovasc Med 2002;3(Suppl. 2): S68 – 75.
  • 12. Martino MA, Borges E, Williamson E, et al. Pulmonary embolism after major abdominal surgery in gynecologic oncology. Obstet Gynecol. 2006 Mar;107(3):666-71.
  • 13. Chisaka H, Utsunomiya H, Okamura K, Yaegashi N. Pulmonary thromboembolism following gynecologic surgery and cesarean section. Int J Gynaecol Obstet. 2004 Jan;84(1):47-53. doi: 10.1016/s0020-7292(03)00339-4. PMID: 14698829.
  • 14. Aysel Sunnetcioglu, Sevdegul Karadas. Mean platelet volume as an indicator of disease in patients with acute pulmonary embolisms. Eastern J Med. 2014; 19(2): 107-111
  • 15. Davis JD. Prevention, diagnosis and treatment of venous thromboembolic complications of gynecologic surgery. Am J Obstet Gynecol 2001;184:759 – 75.
  • 16. Nick AM, Schmeler KM, Frumovitz MM, et al. Risk of thromboembolic disease in patients undergoing laparoscopic gynecologic surgery. Obstet Gynecol. 2010 Oct;116(4):956-961.
  • 17. Cross JJ, Kemp PM, Walsh CG, Flower CD, Dixon AK. A randomized trial of spiral CT and ventilation perfusion scintigraphy for the diagnosis of pulmonary embolism. Clin Radiol 1998 (Mar); 53(3):177 – 82.
  • 18. MacDonald SL, Mayo JR. Computed tomography of acute pulmonary embolism. Semin Ultrasound CT MR 2003 (Aug);24(4):217 – 31.
APA karaman e, AYDINER B, Mermi̇t B, hacıoğlu l (2022). Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. , 596 - 600. 10.5505/ejm.2022.03780
Chicago karaman erbil,AYDINER Burçhan,Mermi̇t Buket,hacıoğlu latif Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. (2022): 596 - 600. 10.5505/ejm.2022.03780
MLA karaman erbil,AYDINER Burçhan,Mermi̇t Buket,hacıoğlu latif Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. , 2022, ss.596 - 600. 10.5505/ejm.2022.03780
AMA karaman e,AYDINER B,Mermi̇t B,hacıoğlu l Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. . 2022; 596 - 600. 10.5505/ejm.2022.03780
Vancouver karaman e,AYDINER B,Mermi̇t B,hacıoğlu l Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. . 2022; 596 - 600. 10.5505/ejm.2022.03780
IEEE karaman e,AYDINER B,Mermi̇t B,hacıoğlu l "Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital." , ss.596 - 600, 2022. 10.5505/ejm.2022.03780
ISNAD karaman, erbil vd. "Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital". (2022), 596-600. https://doi.org/10.5505/ejm.2022.03780
APA karaman e, AYDINER B, Mermi̇t B, hacıoğlu l (2022). Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. Eastern Journal of Medicine, 27(4), 596 - 600. 10.5505/ejm.2022.03780
Chicago karaman erbil,AYDINER Burçhan,Mermi̇t Buket,hacıoğlu latif Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. Eastern Journal of Medicine 27, no.4 (2022): 596 - 600. 10.5505/ejm.2022.03780
MLA karaman erbil,AYDINER Burçhan,Mermi̇t Buket,hacıoğlu latif Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. Eastern Journal of Medicine, vol.27, no.4, 2022, ss.596 - 600. 10.5505/ejm.2022.03780
AMA karaman e,AYDINER B,Mermi̇t B,hacıoğlu l Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. Eastern Journal of Medicine. 2022; 27(4): 596 - 600. 10.5505/ejm.2022.03780
Vancouver karaman e,AYDINER B,Mermi̇t B,hacıoğlu l Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital. Eastern Journal of Medicine. 2022; 27(4): 596 - 600. 10.5505/ejm.2022.03780
IEEE karaman e,AYDINER B,Mermi̇t B,hacıoğlu l "Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital." Eastern Journal of Medicine, 27, ss.596 - 600, 2022. 10.5505/ejm.2022.03780
ISNAD karaman, erbil vd. "Clinical Evaluation of Pulmonary Thromboembolism ın Gynecologic Oncology Operations: Analysis of Nine Patients ın A University Hospital". Eastern Journal of Medicine 27/4 (2022), 596-600. https://doi.org/10.5505/ejm.2022.03780