The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease

OZCAN GÜLSEN, ELVAN; Söke, Fatih; Erkoc Ataoglu, Esra; Gülşen, Çağrı; Kocer, Bilge; BORA TOKCAER, Ayse

doi:10.4274/tnd.2022.99836

The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease

Fatih SÖKE, (Sağlık Bilimleri Üniversitesi, Gülhane Fizyoterapi ve Rehabilitasyon Fakültesi, Nörolojik Fizyoterapi - Rehabilitasyon Anabilim Dalı, Ankara, Türkiye)

ELVAN OZCAN GÜLSEN, (Anadolu Üniversitesi Yunus Emre Sağlık Hizmetleri Meslek Yüksekokulu Yaşlı Bakım Programı, Eskişehir, Türkiye)

Esra Erkoc Ataoglu, (Gazi Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Çağrı GÜLŞEN, (Gazi Üniversitesi Sağlık Bilimleri Fakültesi Fizyoterapi ve Rehabilitasyon Bölümü, Ankara, Türkiye)

Bilge Kocer, (Sağlık Bilimleri Üniversitesi, Dışapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, Ankara, Türkiye)

Ayşe BORA TOKÇAER (Gazi Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Türk Nöroloji Dergisi

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Yıl: 2022 Cilt: 28 Sayı: 2 Sayfa Aralığı: 84 - 90 Metin Dili: İngilizce DOI: 10.4274/tnd.2022.99836 İndeks Tarihi: 28-05-2023

The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease

Öz:

Objective: Although impaired manual dexterity is one of the most disabling symptoms in patients with Parkinson’s disease (PD), there is no reliable and valid patient-reported outcome measure (PROM) for assessing dexterity. Therefore, this study aimed to investigate: (1) The test-retest reliability of the manual ability measure-36 (MAM-36) in patients with PD; (2) the minimum detectable change (MDC) in the MAM-36 scores; (3) the concurrent and known-groups validity of the MAM-36 scores; and (4) the cut-off score that best discriminates patients with PD from healthy individuals. Materials and Methods: This was a cross-sectional study. The MAM-36 was repeated after 4 weeks to determine the test-retest reliability which was calculated with the intraclass correlation coefficient (ICC), Bland-Altman plots, and MDC. The concurrent validity was assessed using correlations between the MAM-36 and nine-hole peg test, Movement Disorders Society Unified Parkinson’s Disease Rating scale (MDS-UPDRS), MDS-UPDRS II, MDS-UPDRS III, Hoehn and Yahr stage, and 8-item PD questionnaire. The known-groups validity was determined by comparing the MAM-36 scores between patients with PD and healthy individuals. Receiver operating characteristic analysis was used to determine the cut-off score for the MAM-36 to best discriminate patients with PD from healthy individuals. Results: Thirty six patients with PD and 32 healthy individuals were included. Excellent test-retest reliability was found (ICC: 0.953). The Bland-Altman plot demonstrated a high agreement. The MDC was 2.33. The MAM-36 had fair to high correlations with the other outcome measurements (correlation coefficients ranged from -0.473 to -0.763, p<0.05 for all). Patients with PD had lower scores than healthy individuals in terms of the MAM-36 (p<0.001). The cut-off score of 76.50 best distinguished patients with PD from healthy individuals. Conclusion: The MAM-36 is a reliable and valid measurement for assessing manual dexterity in patients with PD. It is also the only clinically available PROM in assessing manual dexterity for patients with PD in the Turkish population.

Anahtar Kelime:

Parkinson Hastalarında El Beceri Ölçümü-36’nın Güvenilirlik ve Geçerliliği

Öz:

Amaç: El becerisinde bozulma, Parkinson hastalığı (PH) olan bireylerde en fazla engelleyici semptomlardan biri olmasına rağmen, el becerisini değerlendirmek için güvenilir ve geçerli hasta tarafından bildirilen sonuç ölçümü (PROM) bulunmamaktadır. Bu nedenle, bu çalışma: (1) PH’de el beceri ölçümü-36’nın (EBÖ- 36) test-tekrar test güvenilirliğini; (2) EBÖ-36 puanlarındaki minimal saptanabilir değişimi (MSD); (3) EBÖ-36 puanlarının eşzamanlı ve bilinen gruplar geçerliliğini; ve (4) sağlıklı bireylerden PH’leri en iyi ayıran kesme puanını araştırmayı amaçladı. Gereç ve Yöntem: Bu kesitsel bir çalışmaydı. EBÖ-36, sınıf içi korelasyon katsayısı (ICC), Bland-Altman grafikleri ve MSD ile hesaplanan test-tekrar test güvenilirliğini belirlemek için 4 hafta sonra tekrarlandı. Eş zamanlı geçerlilik, EBÖ-36 ve dokuz delikli peg testi, Hareket Bozuklukları Derneği Birleşik Parkinson Hastalığı Derecelendirme ölçeği (HBD-BPHDÖ), HBD-BPHDÖ II, HBD-BPHDÖ III, Hoehn ve Yahr evresi ve 8 maddelik PH anketi arasındaki korelasyonlar kullanılarak değerlendirildi. Bilinen gruplar geçerliliği, Parkinson hastaları ve sağlıklı bireyler arasında EBÖ-36 puanlarının karşılaştırılmasıyla belirlendi. Alıcı işletim karakteristiği analizi Parkinson hastalarını sağlıklı bireylerden en iyi ayırt eden EBÖ-36’nın kesme puanını belirlemek için kullanıldı. Bulgular: Otuz altı Parkinson hastası ve 32 sağlıklı birey dahil edildi. Mükemmel test-tekrar test güvenilirliği bulundu (ICC: 0,953). Bland-Altman grafiği yüksek bir uyum gösterdi. MSD 2,33’tü. EBÖ-36 diğer sonuç ölçümleri ile orta ila yüksek korelasyonlara sahipti (korelasyon katsayıları -0,473 ile -0,763 arasındaydı, p<0,05 hepsi için). EBÖ-36’da; Parkinson hastaları sağlıklı bireylerden daha düşük puanlara sahipti (p<0,001). 76,50’lik kesme puanı, sağlıklı bireylerden Parkinson hastalarını en iyi ayırt eder. Sonuç: EBÖ-36, Parkinson hastalarında el becerisini değerlendirmek için güvenilir ve geçerli bir ölçümdür. Ayrıca, Türk popülasyonunda Parkinson hastaları için el becerisinin değerlendirilmesinde klinik olarak kullanılabilir tek PROM’dur.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Söke F, OZCAN GÜLSEN E, Erkoc Ataoglu E, Gülşen Ç, Kocer B, BORA TOKCAER A (2022). The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. , 84 - 90. 10.4274/tnd.2022.99836
Chicago	Söke Fatih,OZCAN GÜLSEN ELVAN,Erkoc Ataoglu Esra,Gülşen Çağrı,Kocer Bilge,BORA TOKCAER Ayse The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. (2022): 84 - 90. 10.4274/tnd.2022.99836
MLA	Söke Fatih,OZCAN GÜLSEN ELVAN,Erkoc Ataoglu Esra,Gülşen Çağrı,Kocer Bilge,BORA TOKCAER Ayse The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. , 2022, ss.84 - 90. 10.4274/tnd.2022.99836
AMA	Söke F,OZCAN GÜLSEN E,Erkoc Ataoglu E,Gülşen Ç,Kocer B,BORA TOKCAER A The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. . 2022; 84 - 90. 10.4274/tnd.2022.99836
Vancouver	Söke F,OZCAN GÜLSEN E,Erkoc Ataoglu E,Gülşen Ç,Kocer B,BORA TOKCAER A The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. . 2022; 84 - 90. 10.4274/tnd.2022.99836
IEEE	Söke F,OZCAN GÜLSEN E,Erkoc Ataoglu E,Gülşen Ç,Kocer B,BORA TOKCAER A "The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease." , ss.84 - 90, 2022. 10.4274/tnd.2022.99836
ISNAD	Söke, Fatih vd. "The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease". (2022), 84-90. https://doi.org/10.4274/tnd.2022.99836

APA	Söke F, OZCAN GÜLSEN E, Erkoc Ataoglu E, Gülşen Ç, Kocer B, BORA TOKCAER A (2022). The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. Türk Nöroloji Dergisi, 28(2), 84 - 90. 10.4274/tnd.2022.99836
Chicago	Söke Fatih,OZCAN GÜLSEN ELVAN,Erkoc Ataoglu Esra,Gülşen Çağrı,Kocer Bilge,BORA TOKCAER Ayse The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. Türk Nöroloji Dergisi 28, no.2 (2022): 84 - 90. 10.4274/tnd.2022.99836
MLA	Söke Fatih,OZCAN GÜLSEN ELVAN,Erkoc Ataoglu Esra,Gülşen Çağrı,Kocer Bilge,BORA TOKCAER Ayse The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. Türk Nöroloji Dergisi, vol.28, no.2, 2022, ss.84 - 90. 10.4274/tnd.2022.99836
AMA	Söke F,OZCAN GÜLSEN E,Erkoc Ataoglu E,Gülşen Ç,Kocer B,BORA TOKCAER A The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. Türk Nöroloji Dergisi. 2022; 28(2): 84 - 90. 10.4274/tnd.2022.99836
Vancouver	Söke F,OZCAN GÜLSEN E,Erkoc Ataoglu E,Gülşen Ç,Kocer B,BORA TOKCAER A The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. Türk Nöroloji Dergisi. 2022; 28(2): 84 - 90. 10.4274/tnd.2022.99836
IEEE	Söke F,OZCAN GÜLSEN E,Erkoc Ataoglu E,Gülşen Ç,Kocer B,BORA TOKCAER A "The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease." Türk Nöroloji Dergisi, 28, ss.84 - 90, 2022. 10.4274/tnd.2022.99836
ISNAD	Söke, Fatih vd. "The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease". Türk Nöroloji Dergisi 28/2 (2022), 84-90. https://doi.org/10.4274/tnd.2022.99836