The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience
Yıl: 2022 Cilt: 30 Sayı: 2 Sayfa Aralığı: 206 - 215 Metin Dili: İngilizce DOI: 10.5606/tgkdc.dergisi.2022.21303 İndeks Tarihi: 28-05-2023
The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience
Öz: Background: This study aims to investigate long-term results related to N1 group metastases with respect to anatomical localization and many external parameters and to examine the effect of these parameters on prognosis in patients with in nonsmall cell lung cancer. Methods: Between January 2006 and May 2019, a total of 52 patients (44 males, 8 females; mean age: 59.9±9.5 years; range, 42 to 80 years) who underwent lobectomy due to primary lung malignancy were retrospectively analyzed. The N1 lymph nodes were divided into three anatomical groups as hilar, peribronchial, and intraparenchymal. Demographic features, tumor features, follow-up characteristics, and survival and diseasefree survival parameters were analyzed for each group. The results were also examined in terms of number of metastasis, number of metastatic levels, rate of metastasis, and histopathological type. Results: The five-year survival rate was 66.4% in the peribronchial group and 50% in the hilar group. The five-year disease-free survival rate was 45.7% in the peribronchial group and 37.5% in the hilar group. There was no statistically significant difference between the groups in terms of survival and disease-free survival for anatomical localization, number of metastasis, number of metastatic levels, rate of metastasis, and histopathological type (p>0.05 for all). Conclusion: The structure that would be formed by examining N1 in terms of parameters such as subtitle levels, number of metastasis, number of metastatic stations, rate of metastasis or combinations of these would have a more impact on the decisions in the follow-up and treatment process in this patient population.
Anahtar Kelime: Küçük hücreli dışı akciğer kanserinde izole N1 lenf nodu metastazlarının prognoz üzerine etkileri: Tek merkez deneyimi
Öz: Amaç: Bu çalışmada küçük hücreli dışı akciğer kanseri hastalarında N1 grubu metastazlarının uzun dönem sonuçları anatomik lokalizasyon ve birçok farklı parametre açısından incelendi ve bu parametrelerin prognoz üzerine etkisi araştırıldı. Çalışma planı: Ocak 2006-Mayıs 2019 tarihleri arasında primer akciğer kanseri nedeni ile lobektomi yapılan toplam 52 hasta (44 erkek, 8 kadın; ort. yaş: 59.9±9.5 yıl; dağılım, 42-80 yıl) retrospektif olarak incelendi. N1 lenf nodları hiler, peribronşiyal ve intraparankimal olmak üzere üç anatomik gruba ayrıldı. Her grup demografik özellikler, tümör özellikleri, takip özellikleri ve sağkalım ve hastalıksız sağkalım parametrelerine göre analiz edildi. Sonuçlar ayrıca metastaz sayısı, metastatik düzey sayısı, metastaz oranı ve histopatolojik tip açısından da incelendi. Bulgular: Beş yıllık sağkalım oranı peribronşiyal grupta %66.4 ve hiler grupta %50 idi. Peribronşiyal grupta beş yıllık hastalıksız sağkalım oranı %45.7 ve hiler grupta %37.5 idi. Anatomik lokalizasyon, metastaz sayısı, metastatik düzey sayısı, metastaz oranı ve histopatolojik tip grupları arasında sağkalım ve hastalıksız sağkalım süresi açısından istatistiksel olarak anlamlı bir fark yoktu (hepsi için p>0.05). Sonuç: Alt düzey, metastaz sayısı, metastatik istasyon sayısı, metastaz oranı veya bunların kombinasyonları gibi parametreler kullanılarak N1 incelenmesi ile oluşturulacak bir yapı bu hasta popülasyonunda takip ve tedavi kararlarında daha fazla etkiye sahip olacaktır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | SEZER H, ELİÇORA A (2022). The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. , 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| Chicago | SEZER Hüseyin Fatih,ELİÇORA Aykut The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. (2022): 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| MLA | SEZER Hüseyin Fatih,ELİÇORA Aykut The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. , 2022, ss.206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| AMA | SEZER H,ELİÇORA A The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. . 2022; 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| Vancouver | SEZER H,ELİÇORA A The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. . 2022; 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| IEEE | SEZER H,ELİÇORA A "The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience." , ss.206 - 215, 2022. 10.5606/tgkdc.dergisi.2022.21303 |
| ISNAD | SEZER, Hüseyin Fatih - ELİÇORA, Aykut. "The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience". (2022), 206-215. https://doi.org/10.5606/tgkdc.dergisi.2022.21303 |
| APA | SEZER H, ELİÇORA A (2022). The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. Türk Göğüs Kalp Damar Cerrahisi Dergisi, 30(2), 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| Chicago | SEZER Hüseyin Fatih,ELİÇORA Aykut The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. Türk Göğüs Kalp Damar Cerrahisi Dergisi 30, no.2 (2022): 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| MLA | SEZER Hüseyin Fatih,ELİÇORA Aykut The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. Türk Göğüs Kalp Damar Cerrahisi Dergisi, vol.30, no.2, 2022, ss.206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| AMA | SEZER H,ELİÇORA A The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2022; 30(2): 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| Vancouver | SEZER H,ELİÇORA A The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2022; 30(2): 206 - 215. 10.5606/tgkdc.dergisi.2022.21303 |
| IEEE | SEZER H,ELİÇORA A "The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience." Türk Göğüs Kalp Damar Cerrahisi Dergisi, 30, ss.206 - 215, 2022. 10.5606/tgkdc.dergisi.2022.21303 |
| ISNAD | SEZER, Hüseyin Fatih - ELİÇORA, Aykut. "The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience". Türk Göğüs Kalp Damar Cerrahisi Dergisi 30/2 (2022), 206-215. https://doi.org/10.5606/tgkdc.dergisi.2022.21303 |
