The aim of our study was to investigate the features and agents in patients with dermatophytosis and to evaluate the dermatophyte flora changes in our area in recent years. Patients and Methods: Patients with dermatophytosis were included in our study. The age, gender, social life area, animal contact history of the patients and the clinical types of dermatophytosis were recorded. 443 native preparation positive species were cultured and their pathogens were investigated. There were 367 cases with an age range between 1-79 years. The animal contact history was present in 23,7% and rural area living anamnesis was present in 21.2% of the species having dermatophytosis diagnosis. The ratio of clinical type distributions were determined as follows; T.pedis %41.5, T.unguium on foot+hand %29.2, T.capitis %9.9, T.inguinalis %7.2, T.corporis %6.1, T.manum %3.6, T.facialis %2.0 and T.barba %0.5. The agent could be identified in 76.5% of the species with the rates of T.rubrum 62.5%, T.mentagrophytes 16.8%, T.verrucosum 9.4%, M.canis 4.7%, E.floccosum 3.2%, T.violaceum 1.8%, T.tonsurans 0.9%, M.nanum 0.3 % and T.schonlein 0.3 %. T.rubrum was the most frequent agent causing T.pedis, T.unguium, T.inguinalis. Also T.verrucosum was the most frequent agent in T.capitis, T.corporis and T.barba and it was considered that this could be arised from our animal husbandry region. There have been differentiations in dermatophytosis and their agents today versus their status in 20 years ago in our region. Although they were decreased in comparison to the past, cases with T. capitis have remained their importance at present.