Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study

Yıl: 2021 Cilt: 19 Sayı: 2 Sayfa Aralığı: 87 - 93 Metin Dili: İngilizce DOI: 10.5336/anesthe.2021-85887 İndeks Tarihi: 29-05-2023

Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study

Öz:
bjective: A new viral disease was identified in De- cember 2019, and named COVID-19 by WHO in February 2020. In this article, demographic data, risk factors of the disease, intensive care scores, and the relationship between all these and mortality of patients with COVID-19 severe pneumonia followed in our inten- sive care unit (ICU) were examined. Material and Methods: The data of 865 COVID–19 severe pneumonia patients hospitalized in our ICU between 01-03-2020 and 31-03-2021 were analyzed. De- mographic data, comorbidities, SOFA and APACHEII scores of the patients, and correlation of these parameters with mortality were evaluated. Results: The mean age of the patients was 67.28±14.9. The mean age of the patients in the non-survivor and surviving groups was found to be statistically different (72.41±12.7 vs. 62.08±15.1 respectively). For APACHEII score on first day, the cut- off value was 10.5, which was statistically significant. The effect of SOFA scoring on mortality was analyzed separately for the 1st, 7th, 14th and 28th days. It was found that chronic kidney failure (CKF), heart failure (HF), coronary artery disease (CAD), and neurologic pathology had significant effects on mortality. Mortality was 1.782 times higher for those without CKF, 1.714 times for those without HF, 1.605 times for those without CAD, and 1.331 times for those without Neurological Pathology. Conclusion: Risk factors in patients with COVID-19 severe pneumonia were revealed in detail. While treating the disease, it should be considered that age, presence of ad- ditional disease and intensive care scores are important in the man- agement of the disease.
Anahtar Kelime:

Üçüncü Basamak Yoğun Bakım Ünitesinde Yatan COVID-19 Pnömoni Hastalarının Klinik Özellikleri ve Risk Faktörleri: Retrospektif Tanımlayıcı Çalışma

Öz:
Amaç: İlk olarak Aralık 2019'da Wuhan'da yeni birviral enfek- siyon tanımlandı ve dünyada h ızlı yayılım gösteren bu hastal ık DSÖ tarafından Şubat 2020'de COVID-19 olarak adlandırıldı. Bu makalede COVID-19 ağır pnömonili, yoğun bakımımızda izlenen hastaların de- mografik verileri, risk faktörleri, yoğun bakım skorlamaları ile morta- lite ilişkisi incelenmiştir. Gereç ve Yöntemler: 01 Mart 2020 - 31 Mart 2021 tarihleri aras ında anesteziyoloji yo ğun bakımlarında yatan 865 COVID-19 ağır pnömonisi tan ılı hastanın verileri incelendi. Hastala- rın demografik verileri, ek hastal ıkları, SOFA ve APACHE II skorları ile bu parametrelerin mortalite ile korelasyonu değerlendirildi. Bulgu- lar: Hastaların yaş ortalaması 67.28±14.9 idi. Ölen ve hayatta kalan gruplardaki hastaların yaş ortalamaları istatistiksel olarak farklı bulundu (sırasıyla 72.41±12.7, 62.08±15.1). APACHE II 1.gün skorlar ı için %70,3 duyarlık ve % 66 özgüllük ile cut-off değeri 10,5 olup anlamlı bulundu.SOFA skorlamasının mortalite üzerine etkisi 1,7,14 ve 28. gün- ler için ayrı ayrı incelendi ve tüm zamanlar için bu skorlaman ın mor- talite üzerinde etkisi oldu ğu görüldü. Hastalar ın ek hastal ıkları incelendiğinde kronik böbrek yetmezliği (KBY), kalp yetmezliği (KY), koroner arter hastal ığı (KAH) ve nörolojik patolojinin mortalite üze- rinde anlamlı etkileri bulunmuştur. Mortalite için KBY varlığı 1,782 kat, KY varlığı 1,714 kat, KAH varlığı 1,605 kat ve nörolojik patoloji varlığı ise olmayanlara göre 1,331 kat daha fazla idi.Sonuç: Sonuç ola- rak bu çal ışma ile COVID-19 a ğır pnömoli hastalarda risk faktörleri ayrıntılı olarak ortaya konulmu ştur. Hastalığı tedavi ederken ya ş, ek hastalık varlığı ve yoğun bakım skorlamalarının hastalığın yönetiminde önemli olduğunun dikkate alınması gerekmektedir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik
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APA BASAR H, KAYMAK C, Ozcan A, Nakip M, PARPUCU U, kaçan c, Yalçın H, Kaykaç M (2021). Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. , 87 - 93. 10.5336/anesthe.2021-85887
Chicago BASAR HULYA,KAYMAK CETİN,Ozcan Ayse,Nakip Mert,PARPUCU UMIT MURAT,kaçan ceren,Yalçın Hikmet Furkan,Kaykaç Murat Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. (2021): 87 - 93. 10.5336/anesthe.2021-85887
MLA BASAR HULYA,KAYMAK CETİN,Ozcan Ayse,Nakip Mert,PARPUCU UMIT MURAT,kaçan ceren,Yalçın Hikmet Furkan,Kaykaç Murat Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. , 2021, ss.87 - 93. 10.5336/anesthe.2021-85887
AMA BASAR H,KAYMAK C,Ozcan A,Nakip M,PARPUCU U,kaçan c,Yalçın H,Kaykaç M Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. . 2021; 87 - 93. 10.5336/anesthe.2021-85887
Vancouver BASAR H,KAYMAK C,Ozcan A,Nakip M,PARPUCU U,kaçan c,Yalçın H,Kaykaç M Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. . 2021; 87 - 93. 10.5336/anesthe.2021-85887
IEEE BASAR H,KAYMAK C,Ozcan A,Nakip M,PARPUCU U,kaçan c,Yalçın H,Kaykaç M "Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study." , ss.87 - 93, 2021. 10.5336/anesthe.2021-85887
ISNAD BASAR, HULYA vd. "Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study". (2021), 87-93. https://doi.org/10.5336/anesthe.2021-85887
APA BASAR H, KAYMAK C, Ozcan A, Nakip M, PARPUCU U, kaçan c, Yalçın H, Kaykaç M (2021). Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi, 19(2), 87 - 93. 10.5336/anesthe.2021-85887
Chicago BASAR HULYA,KAYMAK CETİN,Ozcan Ayse,Nakip Mert,PARPUCU UMIT MURAT,kaçan ceren,Yalçın Hikmet Furkan,Kaykaç Murat Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi 19, no.2 (2021): 87 - 93. 10.5336/anesthe.2021-85887
MLA BASAR HULYA,KAYMAK CETİN,Ozcan Ayse,Nakip Mert,PARPUCU UMIT MURAT,kaçan ceren,Yalçın Hikmet Furkan,Kaykaç Murat Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi, vol.19, no.2, 2021, ss.87 - 93. 10.5336/anesthe.2021-85887
AMA BASAR H,KAYMAK C,Ozcan A,Nakip M,PARPUCU U,kaçan c,Yalçın H,Kaykaç M Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi. 2021; 19(2): 87 - 93. 10.5336/anesthe.2021-85887
Vancouver BASAR H,KAYMAK C,Ozcan A,Nakip M,PARPUCU U,kaçan c,Yalçın H,Kaykaç M Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study. Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi. 2021; 19(2): 87 - 93. 10.5336/anesthe.2021-85887
IEEE BASAR H,KAYMAK C,Ozcan A,Nakip M,PARPUCU U,kaçan c,Yalçın H,Kaykaç M "Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study." Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi, 19, ss.87 - 93, 2021. 10.5336/anesthe.2021-85887
ISNAD BASAR, HULYA vd. "Clinical Characteristics and Risk Factors of COVID-19 Pneumonia Patients Hospitalized in a Tertiary Intensive Care Unit: A Retrospective Descriptive Study". Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi 19/2 (2021), 87-93. https://doi.org/10.5336/anesthe.2021-85887