TY  - JOUR
TI  - The Value of Strain Elastography in the Distinction Between  Benign and Malignant Thyroid Nodules in Patients with  Hashimoto Thyroiditis
AB  - BACKGROUND/AIMS: To assess the value of strain elastography (SE) in the distinction between benign and malignant thyroid nodules in  patients with Hashimoto’s thyroiditis (HT). MATERIALS AND METHODS: The study cohort consisted of 74 thyroid nodules in 69 patients with HT. Fine needle aspiration biopsy (FNAB) or  surgical excision were used as the reference standards. Gray-scale properties (internal structure, echogenity, presence or absence of hypoechoic  halo sign, microcalcifications, “taller than wide” sign), vascularity scores, elasticity scores and strain ratios of all nodules were noted and  compared between benign and malignant nodules. Categorical variables were compared using the Pearson chi-square test. Correlation analyses  were performed using the Spearman correlation test. The diagnostic performance of the SE was evaluated using receiver operator characteristic  (ROC) curves. RESULTS: Of the included 74 nodules, 67 (90.5%) and 7 nodules (9.5%) were benign and malignant, respectively. There were significant differences  in echogenicity (p=0.017), peripheral halo (p=0.003), microcalcifications (p<0.001), and margin and shape (p=0.009) characteristics between  benign and malignant nodules. There was a significant association between elasticity scores and histopathological diagnosis of the nodules  (p<0.001). A cut-off point of 6.16 for SR value had sensitivity, specificity, PPV and NPV as 71.4%, 100%, 100% and 97.1%, respectively. Area under  the ROC curve for the diagnostic performance of SR values in the differentiation of benign and malignant nodules was 0.797 (p=0.01) CONCLUSION: Our study revealed that SE is an accurate diagnostic tool to characterize thyroid nodules in patients with HT and this may be  useful to avoiding unnecessary invasive procedures.
AU  - ŞENDUR, HALİT NAHİT
AU  - Cerit, Mahi Nur
AU  - Cindil, Emetullah
AU  - OZHAN OKTAR, SUNA
AU  - Yucel, Cem
AU  - polattas solak, evsen
DO  - 10.4274/cjms.2022.2021-176
PY  - 2023
JO  - Cyprus Journal of Medical Sciences
VL  - 8
IS  - 1
SN  - 2149-7893
SP  - 13
EP  - 19
DB  - TRDizin
UR  - http://search/yayin/detay/1176932
ER  -