The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS

Süleyman SEYHAN, (Acıbadem Mehmet Ali Aydınlar Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı, İstanbul, Türkiye)
guler yalcin, (Marmara Üniversitesi, Eczacılık Fakültesi, Analitik Kimya Anabilim Dalı, İstanbul, Türkiye)
Serap AYAZ SEYHAN (Marmara Üniversitesi, Eczacılık Fakültesi, Analitik Kimya Anabilim Dalı, İstanbul, Türkiye)
Journal of research in pharmacy (online)
3 0
Yıl: 2023 Cilt: 27 Sayı: 1 Sayfa Aralığı: 311 - 319 Metin Dili: İngilizce DOI: 10.29228/jrp.313 İndeks Tarihi: 31-05-2023

The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS

Öz:
Ellagic acid (EA) and resveratrol (RES) are phenolic compounds naturally found in fruits. However, a significant amount of RES and EA is present in berries and their effective isolation enables the production of functional foods. In this study, EA and RES found in four highbush (Vaccinium corymbosum) blueberry varieties (Bluecrop, Brigitta, Darrow and Bluejay) were analyzed simultaneously for the first time. A chromatographic method was developed for EA and RES by HPLC-DAD and LC- MS/MS. Furthermore, pressurized liquid extraction (PLE) method was performed for the extraction of EA and RES from blueberry samples. LOD (limit of detection) and LOQ (limit of quantification) were determined as 0.1898x10-6 mol.L-1 and 0.5694x10-6 mol.L-1 for RES, 0.1271x10-6 mol.L-1 and 0.3814x10-6 mol.L-1 for EA, respectively. All the results were reevaluated according to 91.85% and 84.97% recovery value, for EA and RES, respectively. The amount of EA and RES were found out in the range of 1.65 - 9.16 mg/kg and 2.95 - 9.31 mg/kg in the lyophilized blueberry varieties.
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APA Seyhan S, yalcin g, AYAZ SEYHAN S (2023). The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. , 311 - 319. 10.29228/jrp.313
Chicago Seyhan Süleyman,yalcin guler,AYAZ SEYHAN SERAP The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. (2023): 311 - 319. 10.29228/jrp.313
MLA Seyhan Süleyman,yalcin guler,AYAZ SEYHAN SERAP The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. , 2023, ss.311 - 319. 10.29228/jrp.313
AMA Seyhan S,yalcin g,AYAZ SEYHAN S The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. . 2023; 311 - 319. 10.29228/jrp.313
Vancouver Seyhan S,yalcin g,AYAZ SEYHAN S The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. . 2023; 311 - 319. 10.29228/jrp.313
IEEE Seyhan S,yalcin g,AYAZ SEYHAN S "The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS." , ss.311 - 319, 2023. 10.29228/jrp.313
ISNAD Seyhan, Süleyman vd. "The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS". (2023), 311-319. https://doi.org/10.29228/jrp.313
APA Seyhan S, yalcin g, AYAZ SEYHAN S (2023). The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. Journal of research in pharmacy (online), 27(1), 311 - 319. 10.29228/jrp.313
Chicago Seyhan Süleyman,yalcin guler,AYAZ SEYHAN SERAP The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. Journal of research in pharmacy (online) 27, no.1 (2023): 311 - 319. 10.29228/jrp.313
MLA Seyhan Süleyman,yalcin guler,AYAZ SEYHAN SERAP The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. Journal of research in pharmacy (online), vol.27, no.1, 2023, ss.311 - 319. 10.29228/jrp.313
AMA Seyhan S,yalcin g,AYAZ SEYHAN S The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. Journal of research in pharmacy (online). 2023; 27(1): 311 - 319. 10.29228/jrp.313
Vancouver Seyhan S,yalcin g,AYAZ SEYHAN S The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS. Journal of research in pharmacy (online). 2023; 27(1): 311 - 319. 10.29228/jrp.313
IEEE Seyhan S,yalcin g,AYAZ SEYHAN S "The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS." Journal of research in pharmacy (online), 27, ss.311 - 319, 2023. 10.29228/jrp.313
ISNAD Seyhan, Süleyman vd. "The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LC-MS/MS". Journal of research in pharmacy (online) 27/1 (2023), 311-319. https://doi.org/10.29228/jrp.313
Sayfa Oluşturulma Tarihi
24-04-2024 7:37

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