TY  - JOUR
TI  - Clinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data
AB  - Background. We aimed to determine the number of cystic fibrosis (CF) patients recorded in the Cystic Fibrosis Registry of Türkiye (CFRT) who were in need of lung transplantation (LT) referral and examine clinical differences between patients who were LT candidates due to rapid forced expiratory volume in one second (FEV₁) decline and LT candidates without rapid FEV₁ decline in the last year to identify a preventable cause in patients with such rapid FEV₁ decline. Methods. All CF patients recorded in the CFRT in 2018 were evaluated in terms of LT. Patients were divided into those with FEV₁ below 50% and in need of LT due to a decrease of 20% or more in the previous year (Group 1) and those who did not have FEV₁ decline of more than 20% in the previous year but had other indications for LT (Group 2). Demographic and clinical features were compared between the two groups. Results. Of 1488 patients registered in CFRT, 58 had a need for LT. Twenty patients were included in Group 1 and others in Group 2. Our findings did not reveal any significant variations in treatment, chronic infection status, or complications between the two groups. The average weight z-score was significantly higher in Group 1. Positive correlations were detected between weight z-score and FEV₁ in 2017 in Group 1 and between FEV₁ values in 2017 and 2018 in Group 2. Conclusions. There appears to be a relationship between the nutritional status and weight z-scores of CF patients and pulmonary function, which may indirectly affect the need for lung transplantation referral.
AU  - Bingöl, Ayşen
AU  - BAŞARAN, ERDEM
AU  - Tuğcu, Gökçen Dilşa
AU  - Eryilmaz Polat, Sanem
AU  - Çollak, Abdulhamit
AU  - Uzuner, Selcuk
AU  - Sapan, Nihat
AU  - Onay, Zeynep Reyhan
AU  - Ramasli Gursoy, Tugba
AU  - Kiper, Nural
AU  - Emiralioglu, Nagehan
AU  - cokugras, Haluk Cezmi
AU  - Ozdogan, Sebnem
AU  - Korkmaz, Pervin
AU  - Cekic, Sukru
AU  - TAMAY, ZEYNEP ÜLKER
AU  - Kilic Baskan, Azer
AU  - Kose, Mehmet Alp
AU  - Damadoglu, Ebru
AU  - Sismanlar Eyuboglu, Tugba
AU  - Aslan, Ayse Tana
AU  - KILIÇ, Gonca
AU  - ÇOBANOGLU, NAZAN
AU  - PEKCAN, SEVGI
AU  - ÖZÇELİK, UĞUR
AU  - Dogru, Deniz
AU  - CINEL, GUZIN
AU  - Yalcin, Ebru
AU  - Selimoğlu Şen, Hadice
AU  - ŞEN, velat
AU  - ünal, Gökçen
AU  - YILMAZ, Asli imran
AU  - Kilinc, Ayse Ayzit
AU  - Yazan, Hakan
AU  - Sasihuseyinoglu, Ayse Senay
AU  - ÖZCAN, Dilek
AU  - Altintas, Derya Ufuk
AU  - Kartal Öztürk, Gökçen
AU  - Demir, Esen
AU  - Irmak, Ilim
AU  - Özdemir, Ali
AU  - harmancı, koray
AU  - Hangul, Melih
AU  - Yuksel, Hasan
AU  - ÖZCAN, Gizem
AU  - topal, erdem
AU  - Can, Demet
AU  - Çaltepe, Gönül
AU  - KILIÇ, Mehmet
AU  - CAKIR, Erkan
DO  - 10.24953/turkjped.2021.4930
PY  - 2023
JO  - Turkish Journal of Pediatrics
VL  - 65
IS  - 2
SN  - 0041-4301
SP  - 257
EP  - 268
DB  - TRDizin
UR  - http://search/yayin/detay/1177631
ER  -