Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome
Yıl: 2023 Cilt: 17 Sayı: 1 Sayfa Aralığı: 59 - 62 Metin Dili: İngilizce DOI: 10.5578/ced.20239911 İndeks Tarihi: 01-06-2023
Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome
Öz: Papiliotrema laurentii, previously known as Cryptococcus laurentii, has rarely been diagnosed as the etiological pathogen able to cause human infections. Clinical manifestations of P. laurentii ranges from skin lesions to fungemia. P. laurentii fungemia has been reported extremely rare, especially in patients with risk factors such as chemotherapy, corticosteroids, HIV infection, indwelling central venous catheter and prematurity. This study aimed to report a case of fungemia due to P. laurentii in an infant with Prader Willi syndrome. Despite fluconazole treatment, yeast was isolated three times from blood cultures taken one day apart. Fluconazole was switched to liposomal amphotericin B (5 mg/kg) therapy and continued for two weeks after the first report of unyielded Papiliotrema laurentii. The patient’s clinical condition improved and was discharged home without any complication. To the best of our knowledge, this is the first case of P. laurentii fungemia in an immunocompetent infant.
Anahtar Kelime: Prader Willi Sendromlu Bir Bebekte Papiliotrema (Cryptococcus) laurentii Fungemisi
Öz: Daha önce Cryptococcus laurentii olarak bilinen Papiliotrema laurentii, son derece nadir bir insan patojenidir. P. laurentii’nin klinik bulguları deri lezyonlarından fungemiye kadar geniş bir spektrumda olabilir. P. laurentii fungemisi, özellikle kemoterapi, kortikosteroid tedavisi alan, HIV enfeksiyonu, kalıcı santral venöz kateteri ve prematürite gibi risk faktörleri olan hastalarda son derece nadir olarak bildirilmiştir. Bu yazıda P. laurentii fungemisi gelişen Prader Willi sendromlu bir olgu sunuldu. Flukonazol tedavisine rağmen hastadan bir gün arayla alınan kan kültürlerinde üç kez maya izole edildi. Flukonazol tedavisi amphotericin B (5 mg/kg) tedavisine değiştirildi. Kan kültüründe üreme olmadıktan sonra iki hafta daha tedaviye devam edildi. Klinik durumu düzelen hasta herhangi bir komplikasyon olmadan taburcu edildi. Bildiğimiz kadarıyla, bu immünkompetan bir bebekte P. laurentii fungemisinin ilk örneğidir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | AYDIN Z, Özkaya E, TOSUN I (2023). Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. , 59 - 62. 10.5578/ced.20239911 |
| Chicago | AYDIN Zeynep Gökçe Gayretli,Özkaya Esra,TOSUN Ilknur Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. (2023): 59 - 62. 10.5578/ced.20239911 |
| MLA | AYDIN Zeynep Gökçe Gayretli,Özkaya Esra,TOSUN Ilknur Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. , 2023, ss.59 - 62. 10.5578/ced.20239911 |
| AMA | AYDIN Z,Özkaya E,TOSUN I Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. . 2023; 59 - 62. 10.5578/ced.20239911 |
| Vancouver | AYDIN Z,Özkaya E,TOSUN I Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. . 2023; 59 - 62. 10.5578/ced.20239911 |
| IEEE | AYDIN Z,Özkaya E,TOSUN I "Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome." , ss.59 - 62, 2023. 10.5578/ced.20239911 |
| ISNAD | AYDIN, Zeynep Gökçe Gayretli vd. "Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome". (2023), 59-62. https://doi.org/10.5578/ced.20239911 |
| APA | AYDIN Z, Özkaya E, TOSUN I (2023). Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. Çocuk Enfeksiyon Dergisi, 17(1), 59 - 62. 10.5578/ced.20239911 |
| Chicago | AYDIN Zeynep Gökçe Gayretli,Özkaya Esra,TOSUN Ilknur Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. Çocuk Enfeksiyon Dergisi 17, no.1 (2023): 59 - 62. 10.5578/ced.20239911 |
| MLA | AYDIN Zeynep Gökçe Gayretli,Özkaya Esra,TOSUN Ilknur Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. Çocuk Enfeksiyon Dergisi, vol.17, no.1, 2023, ss.59 - 62. 10.5578/ced.20239911 |
| AMA | AYDIN Z,Özkaya E,TOSUN I Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. Çocuk Enfeksiyon Dergisi. 2023; 17(1): 59 - 62. 10.5578/ced.20239911 |
| Vancouver | AYDIN Z,Özkaya E,TOSUN I Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome. Çocuk Enfeksiyon Dergisi. 2023; 17(1): 59 - 62. 10.5578/ced.20239911 |
| IEEE | AYDIN Z,Özkaya E,TOSUN I "Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome." Çocuk Enfeksiyon Dergisi, 17, ss.59 - 62, 2023. 10.5578/ced.20239911 |
| ISNAD | AYDIN, Zeynep Gökçe Gayretli vd. "Papiliotrema (Cryptococcus) laurentii Fungemia in an Infant with Prader Willi Syndrome". Çocuk Enfeksiyon Dergisi 17/1 (2023), 59-62. https://doi.org/10.5578/ced.20239911 |
