TY  - JOUR
TI  - Comparison of liver resection and living donor liver  transplantation in patients with hepatocellular carcinoma  within Milan criteria and well-preserved liver function
AB  - Background and Aim: Liver resection (LR) and liver transplantation (LT)  are curative treatments for hepatocellular carcinoma (HCC). The main pur pose of this study was to compare the survival of LR and LDLT in patients  with HCC within the Milan criteria. Materials and Methods: The results of the LR (n=67) and LDLT (n=391)  groups were compared for overall survival (OS) and disease-free survival  (DFS). Twenty-six of the HCCs in the LRs met the Milan and Child A cri teria. Also, 200 of the HCC patients in the LDLTs met the Milan criteria, of  which 70 also met the Child A criteria. Results: Early mortality was higher in the LDLT group (13.9% vs 1.47%;  p=0.003). The 5-year OS was higher in the LDLTs than the LRs, but not  statistically significant (84.6% vs 74.2%; p=0.287). However, 5-year DFS  was better in the LDLT group (96.8% vs 64.3%; p<0.001). When the LRs  (n=26) and the LDLTs (n=70) that met both Milan and Child A criteria were  compared, 5-year OS was similar (81.4% vs 74.2%; p=0.512), but DFS was  better in the LDLTs (98.6% vs 64.3%; p<0.001). Conclusion: LR can be justified as the first-line treatment for HCC patients  who meet Milan and Child A criteria in terms of early mortality and OS
AU  - Yilmaz, Sezai
AU  - ince, volkan
AU  - DALDA, YASİN
AU  - Akbulut, Sami
AU  - KARAKAS, SERDAR
AU  - AKATLI, Ayse Nur
AU  - Kahraman, Aysegul Sagir
AU  - Kutlu, Ramazan
AU  - Carr, Brian
DO  - 10.14744/hf.2023.2023.0005
PY  - 2023
JO  - Hepatology forum
VL  - 4
IS  - 2
SN  - 1307-5888
SP  - 47
EP  - 52
DB  - TRDizin
UR  - http://search/yayin/detay/1178884
ER  -