TY  - JOUR
TI  - Ventricular arrhythmias in mitral valve prolapse syndrome and their relationship with electrocardiographic repolarization parameters
AB  - OBJECTIVE: The aim of present study is to compare ventricular and supraventricular arrhythmia incidences in subjects with  and without mitral valve prolapse (MVP) syndrome and to examine if an association exists between ventricular arrhythmias  and repolarization parameters in patients with MVP syndrome. METHODS: This cross-sectional study involved 41 subjects with MVP Syndrome and 41 subjects with palpitation but without  MVP (control group). All subjects were subjected to lead-electrocardiogram, transthoracic echocardiography, and 24-h Holter  monitoring to identify repolarization abnormalities, structural abnormalities, and supraventricular and ventricular arrhythmias.  The QRS width, QTC interval, and Tpeak-Tend intervals were measured for each participant. RESULTS: The number of subjects who had premature ventricular contractions (PVCs), couplets, and non-sustained ven- tricular tachycardia (NSVTs) was significantly higher in the MVP group compared to the control group. Left ventricular end- systolic diameter (LVESD) and left ventricular end-diastolic diameter (LVEDD) and left atrial diameter were also significantly  higher in the MVP group than the control group. QRS width and Tpeak-Tend interval were also significantly higher in subjects  with MVP than the controls. Correlation analysis showed a positive correlation between the severity of mitral regurgitation  (MR) and the number of PVCs and couplets, while there was a significant correlation between left atrium (LA) diameter and  the number of the PVCs and NSVTs. CONCLUSION:  Subjects  with  MVP  experience  ventricular  arrhythmias  more  often  including  PVCs,  couplets,  and  NSVTs  compared to subjects without MVP. LVESD, LVEDD, LA diameter, QRS width, and Tpeak-Tend interval were increased in MVP  subjects than those without MVP. There is an association between the severity of the MR and the frequency of the PVCs,  couplets, or NSVTs.
AU  - ÇEVİK, ERDEM
AU  - Elitok, Ali
AU  - Deniz, Rabia
AU  - Orta, Huseyin
AU  - Engin, Berat
DO  - 10.14744/nci.2021.12058
PY  - 2023
JO  - İstanbul Kuzey Klinikleri
VL  - 10
IS  - 2
SN  - 2148-4902
SP  - 205
EP  - 211
DB  - TRDizin
UR  - http://search/yayin/detay/1178921
ER  -