TY  - JOUR
TI  - Gastrointestinal endoscopic findings of autoimmune and autoinflammatory diseases in pediatric rheumatology patients
AB  - OBJECTIVE: Rheumatic diseases in children are chronic and multisystemic diseases. In this study, it was aimed to evaluate  gastrointestinal endoscopic findings in children diagnosed as autoimmune or autoinflammatory rheumatic diseases consulted  with pediatric gastroenterology for gastrointestinal complaints. METHODS: The patients followed up by the Pediatric Rheumatology Department and consulted to the Pediatric Gastroenterology  Department due to gastrointestinal complaints were included in the study. File records of the patients were analyzed retrospectively. RESULTS: A total of 28 patients were included in the study. Twelve of the patients had autoimmune disease (Juvenile idio- pathic arthritis [JIA], systemic lupus erythematosus, Sjögren’s syndrome, and scleroderma) and the other 16 had autoinflam- matory disease (familial Mediterrnean fever, hyper Immunoglobulin D syndrome, undifferantiated systemic autoinflammatory  disease, and systemic JIA). Four of the patients with familial Mediterrnean fever also diagnosed as JIA. The mean age of the  patients was 11.7±3.5 years. The main gastrointestinal complaints of patients with both autoimmune and autoinflammatory  diseases were abdominal pain and diarrhea. Inflammatory bowel disease was found in 33% of those with autoimmune dis- ease and 56% of those with autoinflammatory disease in patients underwent endoscopic evaluation. M694V mutation was  present in 62% of the patients with autoinflammatory disease presented with gastrointestinal complaints. CONCLUSION:  Both  autoimmune  and  autoinflammatory  rheumatic  diseases  can  cause  gastrointestinal  complaints  and  should be referred to a pediatric gastroenterologist for early diagnosis.
AU  - Pac Kisaarslan, Aysenur
AU  - Altay, Derya
AU  - ARSLAN, DURAN
DO  - 10.14744/nci.2021.62713
PY  - 2023
JO  - İstanbul Kuzey Klinikleri
VL  - 10
IS  - 2
SN  - 2148-4902
SP  - 228
EP  - 236
DB  - TRDizin
UR  - http://search/yayin/detay/1178927
ER  -