Yıl: 2023 Cilt: 27 Sayı: 2 Sayfa Aralığı: 44 - 47 Metin Dili: İngilizce DOI: 10.5152/erp.2023.22130175 İndeks Tarihi: 03-06-2023

Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes

Öz:
Objective: The conventional approach to brittle diabetes is the treatment of underlying causes and optimization with multiple-dose insulin injections. The goal of multiple-dose insulin therapy is to exactly mimic physiological insulin secretion; however, it often results in hypoglycemia. This study investigates the effectiveness of continuous subcutaneous insulin infusion therapy with a patch pump with the sensor augmented with predictive low-glucose suspend algorithm system in patients with uncontrolled type 1 diabetes who were treated with multiple-dose insulin and have high gly - cated hemoglobin values. Methods: The data of patients whose glycemic control could not be achieved with multiple-dose insulin therapy and who were switched to sensor-augmented tubeless pump with predictive low- glucose suspend feature (Medtrum A7+ TouchCare patch pump and integrated A7+ continuous glu- cose monitoring system) were analyzed retrospectively. Results: A total of 16 patients (male: 9; 56.3%) were included. After 3 months of the sensor-aug- mented pump with predictive low-glucose suspend treatment, patients’ median (interquartile range) glycated hemoglobin level decreased to 7.55 (1.43) from 9.20 (3.55) (P = .008). Time below 56 mg/dL was 0.34%, time between 56 and 70 mg/dL was 1.01%, time between 70 and 180 mg/dL was 72.90%, time above 180 mg/dL was 25.67%, time between 70and 250 mg/dL was 95.98%, and time above 250 mg/dL was 2.76%. Conclusions: A pump system with predictive low-glucose suspend feature improves glycemic targets in patients with brittle uncontrolled type 1 diabetes without the expense of hypoglycemia compared to multiple-dose insulin treatment.
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APA YILMAZ M, Telci Caklili O, Hacisahinogullari H, Cakmak R, şahiner e, keskin f (2023). Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. , 44 - 47. 10.5152/erp.2023.22130175
Chicago YILMAZ MEHMET TEMEL,Telci Caklili Ozge,Hacisahinogullari Hulya,Cakmak Ramazan,şahiner elif,keskin fatma Ela Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. (2023): 44 - 47. 10.5152/erp.2023.22130175
MLA YILMAZ MEHMET TEMEL,Telci Caklili Ozge,Hacisahinogullari Hulya,Cakmak Ramazan,şahiner elif,keskin fatma Ela Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. , 2023, ss.44 - 47. 10.5152/erp.2023.22130175
AMA YILMAZ M,Telci Caklili O,Hacisahinogullari H,Cakmak R,şahiner e,keskin f Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. . 2023; 44 - 47. 10.5152/erp.2023.22130175
Vancouver YILMAZ M,Telci Caklili O,Hacisahinogullari H,Cakmak R,şahiner e,keskin f Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. . 2023; 44 - 47. 10.5152/erp.2023.22130175
IEEE YILMAZ M,Telci Caklili O,Hacisahinogullari H,Cakmak R,şahiner e,keskin f "Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes." , ss.44 - 47, 2023. 10.5152/erp.2023.22130175
ISNAD YILMAZ, MEHMET TEMEL vd. "Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes". (2023), 44-47. https://doi.org/10.5152/erp.2023.22130175
APA YILMAZ M, Telci Caklili O, Hacisahinogullari H, Cakmak R, şahiner e, keskin f (2023). Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. Endocrinology research and practice, 27(2), 44 - 47. 10.5152/erp.2023.22130175
Chicago YILMAZ MEHMET TEMEL,Telci Caklili Ozge,Hacisahinogullari Hulya,Cakmak Ramazan,şahiner elif,keskin fatma Ela Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. Endocrinology research and practice 27, no.2 (2023): 44 - 47. 10.5152/erp.2023.22130175
MLA YILMAZ MEHMET TEMEL,Telci Caklili Ozge,Hacisahinogullari Hulya,Cakmak Ramazan,şahiner elif,keskin fatma Ela Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. Endocrinology research and practice, vol.27, no.2, 2023, ss.44 - 47. 10.5152/erp.2023.22130175
AMA YILMAZ M,Telci Caklili O,Hacisahinogullari H,Cakmak R,şahiner e,keskin f Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. Endocrinology research and practice. 2023; 27(2): 44 - 47. 10.5152/erp.2023.22130175
Vancouver YILMAZ M,Telci Caklili O,Hacisahinogullari H,Cakmak R,şahiner e,keskin f Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes. Endocrinology research and practice. 2023; 27(2): 44 - 47. 10.5152/erp.2023.22130175
IEEE YILMAZ M,Telci Caklili O,Hacisahinogullari H,Cakmak R,şahiner e,keskin f "Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes." Endocrinology research and practice, 27, ss.44 - 47, 2023. 10.5152/erp.2023.22130175
ISNAD YILMAZ, MEHMET TEMEL vd. "Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes". Endocrinology research and practice 27/2 (2023), 44-47. https://doi.org/10.5152/erp.2023.22130175