Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis
Yıl: 2022 Cilt: 28 Sayı: 2 Sayfa Aralığı: 77 - 82 Metin Dili: İngilizce DOI: 10.4274/tod.galenos.2021.65037 İndeks Tarihi: 06-06-2023
Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis
Öz: Objective: The aims of this study are to compare bone mineral densitometry and magnetic resonance imaging (MRI) findings in postmenopausal women diagnosed with osteoporosis and the investigation of the effectiveness of MRI in the diagnosis of osteoporosis. Materials and Methods: Forty female patients, 50 years of age or older who underwent lumbar MRI examination and were diagnosed with dual-energy X-ray absorptiometry (DEXA) osteoporosis were included in our study. Forty healthy women aged 20-29 years with lumbar MRI examinations were included in the control group. On sagittal T1-weighted (T1W) images of individuals in the patient and control groups signal to-noise ratio (SNR) was measured from L1-L4 vertebrae. To facilitate the diagnosis of osteoporosis, a quantitative score called the M-score was obtained using SNR values. The relationship between DEXA and the obtained SNR and M-score values were investigated. Results: In the patient group, median SNR values of L1, L2, L3, L4 vertebrae obtained from T1-weighted sequence was 57.49 (25.18-182.48), and they were 24.90 (7.40-41.70) in the control group. Receiver operating characteristics analysis was performed for L1, L2, L3, L4 vertebrae. The area under the curve for the mean value of L1-L4 vertebra was found to be 0.966 (p<0.001), and the 95% confidence interval was found 0.933-1.000. The mean SNR predictive value of L1-L4 was calculated as 33.45, and sensitivity for this value was found to be 90%, and specificity was found to be 90%. There was a negative correlation between lumbar MRI SNR-DEXA (p>0.05) and M score-DEXA (p>0.05). Conclusion: It has been concluded that L1-L4 vertebral SNR measurement in T1-weighted sequence in lumbar MRI can be used to distinguish osteoporosis patients from normal individuals. Thus, osteoporosis can be diagnosed without X-ray exposure.
Anahtar Kelime: Osteoporozlu Kadınlarda Lomber Spinal Manyetik Rezonans Görüntülemenin Tanıya Katkısının Değerlendirilmesi
Öz: Amaç: Bu çalışmanın amacı osteoporoz tanılı postmenopozal kadınlarda kemik mineral dansitometri ve manyetik rezonans görüntüleme (MRG) bulgularının karşılaştırılması ve osteoporoz tanısında MRG’nin etkinliğinin araştırılmasıdır. Gereç ve Yöntem: Çalışmamıza 6 ay içerisinde lomber MRG incelemesi yapılan ve dual-enerji X-ışını absorbsiyometri (DEXA) ile osteoporoz tanısı almış 50 yaş ve üstü 40 kadın hasta dahil edildi. Kontrol grubunda lomber MRG incelemesi bulunan 20-29 yaşlarında 40 sağlıklı kadın incelendi. Hasta ve kontrol grubundaki bireylerin sagittal T1 ağırlıklı görüntülerinde L1-L4 vertebralardan sinyal gürültü oranı (SNR) ölçümü yapıldı. Osteoporoz tanısında kolaylık sağlaması için SNR değerleri kullanılarak M-skoru adında kantitatif bir skor elde edildi. Elde edilen SNR ve M-skoru değerleri ile DEXA arasındaki ilişki araştırıldı. Bulgular: L1, L2, L3, L4 vertebralarının T1 ağırlıklı sekanstan elde edilen SNR ortanca değerleri hasta grubunda 57,49 (25,18-182,48), kontrol grubunda 24,90 (7,40-41,70) idi. L1, L2, L3, L4 vertebralarının alıcı işletim karakteristiği analizi yapıldı. L1-L4 vertebra ortalama değeri için eğri altında kalan alan 0,966 (p<0,001), %95 güven aralığı 0,933-1,000 bulundu. L1-L4 ortalama SNR kestirim değeri 33,45 olarak hesaplanmış olup bu değer için duyarlılık %90, özgünlük %90 olarak bulundu. Lomber MRG SNR-DEXA (p>0,05) ile M-skoru-DEXA arasında negatif yönlü bir ilişki saptandı (p>0,05). Sonuç: Lomber MRG’de T1 ağırlıklı sekansta L1-L4 vertebra SNR ölçümünün osteoporozlu hastaları normal bireylerden ayırt etmede kullanılabileceği sonucuna varılmıştır. Böylece osteoporoz, röntgen ışınlarına maruz kalmadan teşhis edilebilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Atik I, Atik S, Gul E, BULUT S (2022). Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. , 77 - 82. 10.4274/tod.galenos.2021.65037 |
| Chicago | Atik Irfan,Atik Seda,Gul Enes,BULUT SEMA Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. (2022): 77 - 82. 10.4274/tod.galenos.2021.65037 |
| MLA | Atik Irfan,Atik Seda,Gul Enes,BULUT SEMA Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. , 2022, ss.77 - 82. 10.4274/tod.galenos.2021.65037 |
| AMA | Atik I,Atik S,Gul E,BULUT S Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. . 2022; 77 - 82. 10.4274/tod.galenos.2021.65037 |
| Vancouver | Atik I,Atik S,Gul E,BULUT S Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. . 2022; 77 - 82. 10.4274/tod.galenos.2021.65037 |
| IEEE | Atik I,Atik S,Gul E,BULUT S "Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis." , ss.77 - 82, 2022. 10.4274/tod.galenos.2021.65037 |
| ISNAD | Atik, Irfan vd. "Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis". (2022), 77-82. https://doi.org/10.4274/tod.galenos.2021.65037 |
| APA | Atik I, Atik S, Gul E, BULUT S (2022). Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. Türk Osteoporoz Dergisi, 28(2), 77 - 82. 10.4274/tod.galenos.2021.65037 |
| Chicago | Atik Irfan,Atik Seda,Gul Enes,BULUT SEMA Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. Türk Osteoporoz Dergisi 28, no.2 (2022): 77 - 82. 10.4274/tod.galenos.2021.65037 |
| MLA | Atik Irfan,Atik Seda,Gul Enes,BULUT SEMA Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. Türk Osteoporoz Dergisi, vol.28, no.2, 2022, ss.77 - 82. 10.4274/tod.galenos.2021.65037 |
| AMA | Atik I,Atik S,Gul E,BULUT S Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. Türk Osteoporoz Dergisi. 2022; 28(2): 77 - 82. 10.4274/tod.galenos.2021.65037 |
| Vancouver | Atik I,Atik S,Gul E,BULUT S Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis. Türk Osteoporoz Dergisi. 2022; 28(2): 77 - 82. 10.4274/tod.galenos.2021.65037 |
| IEEE | Atik I,Atik S,Gul E,BULUT S "Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis." Türk Osteoporoz Dergisi, 28, ss.77 - 82, 2022. 10.4274/tod.galenos.2021.65037 |
| ISNAD | Atik, Irfan vd. "Contribution of Lumbar Vertebral Magnetic Resonance Imaging to Diagnosis in Women with Osteoporosis". Türk Osteoporoz Dergisi 28/2 (2022), 77-82. https://doi.org/10.4274/tod.galenos.2021.65037 |
