Yıl: 2023 Cilt: 28 Sayı: 2 Sayfa Aralığı: 219 - 227 Metin Dili: İngilizce DOI: 10.5505/ejm.2023.28003 İndeks Tarihi: 06-06-2023

Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography

Öz:
The present study investigates the clinical, hormonal and biochemical differences between patients with polycystic ovary syndrome (PCOS), patients with polycystic ovary image (PCO -like) and a normal control group with no polycystic image syndrome. Included in the study were 238 patients who presented to the Department of Obstetrics and Gynecology of Eskisehir Osmangazi University between December 2012 and December 2013 with complaints of infertility. A physical and pelvic examination of all patients was performed and their ovaries were evaluated with TVUS, and blood samples were taken for hormonal tests. The patients were categorized into three groups based on their clinical and endocrinological characteristics as: 77 cases with PCOS, 74 cases with PCO-like findings and 87 cases recruited as normal controls. BMI and the rate of android obesity was found to be higher in patients with PCOS. Clinical and laboratory findings of hyperandrogenism were more commonly encountered in patients with PCOS. FG scores were found to be increased, and correlated with BMI, waist / hip ratio, free blood testosterone (f T) and total testosterone (TT) (p<0.001). AFC decreased in the control group with increased age (p=0,003) but no such association found in the PCOS (p=0.216) and PCO-like group (p=0.876). Not every patient identified with a PCO image on ultrasonography has PCOS, and so clinical, hormonal and biochemical properties should be evaluated in detail when patients with PCO -like findings are encountered, and they should be differentiated from patients with PCOS. Patients with PCOS should be evaluated in detail and followed-up to prevent long-term complications.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Knochenhauer ES, Key TJ, Kahsar-Miller M, et al. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: A prospective study. J Clin Endocrinol Melab 83:3078-3082,1998.
  • 2. Farah L, Lazenby AJ, Boots LR, et al. Prevalence of polycystic ovary syndrome in women seeking treatment from community electrologists (Alabama Professional Electrology Association Study Group). J Reprod Med 44:870-974,1999.
  • 3. Diamanti-Kandarakis E, Kouli CR, Bergiele AT, et al. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: Hormonal and metabolic profile. J Clin Endocrinol Metab 84:40064011,1999.
  • 4. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004;81:19-25.
  • 5. PolsonDW, AdamsJ, WadsworrthJ, FranksS. Polycysicovaries-a common finding in normal women. Lancet 1988; 870-2.
  • 6. Clayton RN, Agden V, Hodglanson J, et al. How common are polycystic ovaries in normal women and what is their significance for the fertility of the population. Clin Endocrinol 1992; 37: 127-34.
  • 7. Farguhar CM, Birdsall M. The Prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women. Aust N Z J Obstet Gynaecol 1990; 34: 67-72.
  • 8. Ahmadi A, Akbarzadeh M, Mohammadi F, Akbari M, Jafari B, Tolide-Ie HR, et all.Anthropometric characteristics and dietary pattern of women with polycystic ovary syndrome. İndian J. Endocrinol Metab. 2013;17(4):672-6
  • 9. Uçkan K, Demir H, Baskıran Y, Demir C. Investigation of activities enzyme Prolidase (PRO) and Glutathione S-Transferase (GST) in polycystic ovary syndrome (PCOS) patients. Journal of Scientific Reports -A ;2022 ,(050), 20-31.
  • 10. Baldani DP, Skrgatic L, Goldstajn MS, et al: Clinical and biochemical characteristics of polycystic ovary syndrome in Croatian population. Coll Antropol. 36:1413–1418. 2012.
  • 11. Faria FR, Gusmão LS, Faria ER, Gonçalves VS, Cecon RS, Franceschini Sdo C, Priore SE, et all. Polycystic Ovary Sendrome and intervening factors in adolescents from 15 – 18 years old. Rev. Assoc. Med. Bras. 2013;59(4):341-6
  • 12. Esmaeilzadeh S, Delaver MA, Amiri M, Khafri S, Pasha NG, et all. Polycystic Ovary Sendrome in İranian adolescents. Int. J. Adolesc. Med. Health. 2014;22:1-7.
  • 13. De Sousa RM, Chein MB, da Silva DS, Dutra MB, Navarro PA, de Figueiredo Neto JA, Brito LM, et all. Metabolic profile in women of different body mass indices with polycystic ovary syndrome. Rev. Bras. Ginecol. Obstet. 2013;35(9):413-20
  • 14. Azziz R, Carmina E, Dewailly D et al. Androgen Excess Society. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. J Clin Endocrinol Metab.2006;91:4237-45.
  • 15. Ugwu GO, Iyoke CA, Onah HE, Mba SG. Prevalence, presentation and management of polycystic ovary syndrome in Enugu, south east Nigeria. Niger J Med. 2013;22(4):313-6
  • 16. Coskun A, Ercan O, Arikan DC, Özer A, Kilinc M, Kiran G, Kostu B. Modified Ferriman- Gallwey hirsutism score and androgen levels in Turkish women.Eur J Obstet Gynecol Reprod Biol. 2011;154(2):167-71
  • 17. Zhang HY, Guo CX, Zhu FF, Qu PP, Lin WJ, Xiong J. Clinical characteristics, metabolic features, and phenotype of Chinese women with polycystic ovary syndrome: a large-scale case-control study. Arch Gynecol Obstet. 2013;287(3):525-31
  • 18. Baldani DP, Skrgatić L, Simunić V, Zlopasa G, Canić T, Trgovcić I. Characteristics of different phenotypes of polycystic ovary syndrome based on the Rotterdam criteria in the Croatian population. Coll Antropol. 2013;37(2):477-82
  • 19. Ates S, Sevket O, Sudolmus S, Dane B, Ozkal F, Uysal O, Dansuk R. Different phenotypes of polycystic ovary syndrome in Turkish women: clinical and endocrine characteristics. Gynecol Endocrinol. 2013;29(10):931-5
  • 20. Veltman-Verhulst SM1, Goverde AJ, van Haeften TW, Fauser BC. Fasting glucose measurement as a potential first step screening for glucose metabolism abnormalities in women with anovulatory polycystic ovary sendrome. Hum. Reprod.2013;28(8):2228-34
  • 21. Lerchbaum E, Schwetz V, Giuliani A, Obermayer-Pietsch B. Assessment of glucose metabolism in polycystic ovary syndrome: HbA1c or fasting glucose compared with the oral glucose tolerance test as a screening method. Hum. Reprod.2013;28(9):2537-44
  • 22. Conway GS, Honour JW, Jacobs HS. Heterogeneity of the polycystic ovary syndrome: clinical, endocrine and ultrasound features in 556 patients. Clin Endocrinol (Oxf) 1989;30:459-70
  • 23. Legro RS, Myers ER, Barnhart HX et al. The pregnancy in polycystic ovary syndrome (PPCOS) study: baseline characteristics of the randomized cohort including racial effects. Fertil Steril 2006;86:914-33
  • 24. Hahn S, Tan S, Elsenbruch S et al. Clinical and biochemical characterization of women with polycystic ovary syndrome in North Rhine-Westphalia. Horm Metab Res 2005;37:438-44
  • 25. Rehme MF, Pontes AG, Corrente JE, Franco JG Jr, Pontes A. Contribution of hyperandrogenism to the development of metabolic syndrome in obese women with polycystic ovary syndrome. Rev Bras Ginecol Obstet. 2013;35(12):562-8
  • 26. Li L, Chen X, He Z, Zhao X, Huang L, Yang D. Clinical and metabolic features of polycystic ovary syndrome among Chinese adolescents. J Pediatr Adolesc Gynecol. 2012;25(6):390-5
  • 27. Wiser A, Shalom-Paz E, Hyman JH, Sokal- Arnon T, Bantan N, Holzer H, Tulandi T. Age-related normogram for antral follicle count in women with polycyctic ovary sendrome. Reprod. Biomed. Online 2013;27(4);414-8
  • 28. Nardo LG, Christodoulou D, Gould D, Roberts SA, Fitzgerald CT, Laing I. Anti- Müllerian hormone levels and antral follicle count in women enrolled in in vitro fertilization cycles:relationship to lifestyle factors, chronological age and reproductive history. Gynecol Endocrinol. 2007;23(8):486- 93.
APA Bağcı M, Tekin A (2023). Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. , 219 - 227. 10.5505/ejm.2023.28003
Chicago Bağcı Mustafa,Tekin Ahmet Başar Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. (2023): 219 - 227. 10.5505/ejm.2023.28003
MLA Bağcı Mustafa,Tekin Ahmet Başar Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. , 2023, ss.219 - 227. 10.5505/ejm.2023.28003
AMA Bağcı M,Tekin A Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. . 2023; 219 - 227. 10.5505/ejm.2023.28003
Vancouver Bağcı M,Tekin A Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. . 2023; 219 - 227. 10.5505/ejm.2023.28003
IEEE Bağcı M,Tekin A "Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography." , ss.219 - 227, 2023. 10.5505/ejm.2023.28003
ISNAD Bağcı, Mustafa - Tekin, Ahmet Başar. "Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography". (2023), 219-227. https://doi.org/10.5505/ejm.2023.28003
APA Bağcı M, Tekin A (2023). Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. Eastern Journal of Medicine, 28(2), 219 - 227. 10.5505/ejm.2023.28003
Chicago Bağcı Mustafa,Tekin Ahmet Başar Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. Eastern Journal of Medicine 28, no.2 (2023): 219 - 227. 10.5505/ejm.2023.28003
MLA Bağcı Mustafa,Tekin Ahmet Başar Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. Eastern Journal of Medicine, vol.28, no.2, 2023, ss.219 - 227. 10.5505/ejm.2023.28003
AMA Bağcı M,Tekin A Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. Eastern Journal of Medicine. 2023; 28(2): 219 - 227. 10.5505/ejm.2023.28003
Vancouver Bağcı M,Tekin A Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography. Eastern Journal of Medicine. 2023; 28(2): 219 - 227. 10.5505/ejm.2023.28003
IEEE Bağcı M,Tekin A "Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography." Eastern Journal of Medicine, 28, ss.219 - 227, 2023. 10.5505/ejm.2023.28003
ISNAD Bağcı, Mustafa - Tekin, Ahmet Başar. "Evaluation of Patients Identified with Polycystic Ovary Image on Ultrasonography". Eastern Journal of Medicine 28/2 (2023), 219-227. https://doi.org/10.5505/ejm.2023.28003