TY  - JOUR
TI  - Anti-parietal cell antibody positivity in women with poor obstetric history and skin disorders: significance of preconception counseling
AB  - Purpose: The aim of this study was vto demonstrate the impact of anti-parietal cell antibody (APCA) positivity in women with poor obstetric history and skin disorders. Materials and Methods: This retrospective cohort consisted of 63 women having skin disorders and poor obstetric history. Patients were grouped into the control (women with skin disorders only, n=50) and study groups (women with skin disorders and APCA positivity, n=13). The study groups were compared in terms of demographic findings, BOI, and risk factors for placenta-related obstetric complications. Results: APCA (+) and APCA (–) groups showed no statistically significant difference in terms of demographic findings such as age, gravidity, parity, BOI, and the number of miscarriages.. We have demonstrated that 69.2% (9/13) of the APCA (+) cases have two or more skin diseases, while 34% of APCA (-) women have multiple skin diseases. There was a statistically significant difference between APCA (+) and APCA (–) groups in terms of the presence of single or multiple skin diseases (p=0.029). We could not demonstrate a statistically significant difference between APCA (+) and APCA (–) patients in terms of the presence of risk factors for obstetric complications such as immune system problems, MTHFR polymorphisms, hereditary thrombophilia, and diabetes mellitus type-2. Conclusion: APCA positivity which is a risk factor for obstetric complications might be a good indicator used to identify susceptibility to multiple skin disorders during preconception counseling.
AU  - Beksac, M.Sinan
AU  - DÖNMEZ, HANİFE GÜLER
AU  - Beksaç, Burcu
AU  - Cagan, Murat
DO  - 10.17826/cumj.1168878
PY  - 2023
JO  - Cukurova Medical Journal
VL  - 48
IS  - 1
SN  - 2602-3032
SP  - 278
EP  - 282
DB  - TRDizin
UR  - http://search/yayin/detay/1181525
ER  -