Folk songs are one of the cultural elements that reflect the life style of Turkish people, their socio-cultural characteristics, their experiences in the historical process, their religious beliefs, traditions and customs. In addition, folk songs are products of oral literature that reflect the reactions and feelings of the society against the events experienced. Therefore, folk songs have an important place in folklore studies since they concern both the social life of the people, their music and poetry. Turkish folklore has been kept alive in Thessaloniki region, which is one of the important cities of Turkish history. The importance of folk songs in this folklore is quite high. Vocabulary of the Turkish language is revealed with reference to works such as literary works, poems, historical texts, as well as folk songs that belong to oral culture. Until now, studies on Thessaloniki have been made, but no study has been done on the vocabulary in folk songs. Based on this shortcoming, in this research, it is aimed to determine the vocabulary and cultural motifs in Selanik folk songs. Descriptive method was used in the study. In this context, twenty-six folk songs belonging to Thessaloniki region, which were reached from the sources of the Turkish Radio and Television Corporation (TRT), were examined by document analysis. The analyzed Selanik folk songs have been classified in terms of their subjects and examples of folk songs that are suitable for the classification have been given. In addition, it is seen that cultural motifs of the region, landforms and outdoor elements, climate, animals, plants, religious elements, colors, names of women and men, relatives, clothing and jewelry, used items, food and beverage and organ names are used in folk songs. As a result of the research, it was determined that the vocabulary in the folk songs of Selanik region is closely related to the cultural texture of the region. It would be beneficial to use these folk songs for cultural transfer at different levels of schools. The lack of many studies and written sources about Selanik folk songs, especially in terms of content, sound, word and sentence analysis, has caused the study to be limited.