Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer

bolukbasi, yasemin; SELEK, UGUR; BINGOLBALI, AYHAN; Saglam, Yucel

doi:10.4274/eamr.galenos.2023.69077

Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer

Yücel SAĞLAM, (Koç Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Yasemin BÖLÜKBAŞI, (Koç Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Ayhan BİNGÖLBALI, (Yıldız Teknik Üniversitesi Tıp Fakültesi, Biyomühendislik Anabilim Dalı, İstanbul, Türkiye)

Uğur SELEK (Koç Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

European Archives of Medical Research

3 0

Yıl: 2023 Cilt: 39 Sayı: 2 Sayfa Aralığı: 95 - 102 Metin Dili: İngilizce DOI: 10.4274/eamr.galenos.2023.69077 İndeks Tarihi: 04-07-2023

Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer

Öz:

Objective: In order to seek a lower toxicity risk prediction in patients with prostate cancer, we have evaluated whether prescribing a potential hybrid radiotherapy of intensity-modulated radiotherapy (IMRT) & volumetric modulated arc therapy (VMAT) optimization might increase sparing of organs at risk (OAR) and target dose conformity. Methods: The cohort for this dosimetric planning study included ten consecutive prostate cancer patients previously treated with double arc VMAT to 78 Gy. New optimized hybrid arc plans for a combination of IMRT (8 step-and-shoot fix fields: 225°, 260°, 295°, 330°, 30°, 65°, 90°, 135°) and VMAT (182°-178° clockwise) besides new IMRT (8 step-and-shoot fix fields: 225°, 260°, 295°, 330°, 30°, 65°, 90°, 135°) plans were generated per patient. Dose volume histogram parameters were compared between treated VMAT, new IMRT and new optimized hybrid arc plans for OAR doses. Results: The optimized hybrid arc technique revealed significantly lower rectum (p=0.005) and bladder (p= 0.005) doses compared to stand alone VMAT and IMRT. Conclusion: The optimized hybrid arc technique appears to combine the advantages of IMRT and VMAT to provide a more conformal and homogeneous plan with better OAR sparing in comparison to standalone VMAT or IMRT plans.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Saglam Y, bolukbasi y, BINGOLBALI A, SELEK U (2023). Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. , 95 - 102. 10.4274/eamr.galenos.2023.69077
Chicago	Saglam Yucel,bolukbasi yasemin,BINGOLBALI AYHAN,SELEK UGUR Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. (2023): 95 - 102. 10.4274/eamr.galenos.2023.69077
MLA	Saglam Yucel,bolukbasi yasemin,BINGOLBALI AYHAN,SELEK UGUR Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. , 2023, ss.95 - 102. 10.4274/eamr.galenos.2023.69077
AMA	Saglam Y,bolukbasi y,BINGOLBALI A,SELEK U Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. . 2023; 95 - 102. 10.4274/eamr.galenos.2023.69077
Vancouver	Saglam Y,bolukbasi y,BINGOLBALI A,SELEK U Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. . 2023; 95 - 102. 10.4274/eamr.galenos.2023.69077
IEEE	Saglam Y,bolukbasi y,BINGOLBALI A,SELEK U "Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer." , ss.95 - 102, 2023. 10.4274/eamr.galenos.2023.69077
ISNAD	Saglam, Yucel vd. "Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer". (2023), 95-102. https://doi.org/10.4274/eamr.galenos.2023.69077

APA	Saglam Y, bolukbasi y, BINGOLBALI A, SELEK U (2023). Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. European Archives of Medical Research, 39(2), 95 - 102. 10.4274/eamr.galenos.2023.69077
Chicago	Saglam Yucel,bolukbasi yasemin,BINGOLBALI AYHAN,SELEK UGUR Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. European Archives of Medical Research 39, no.2 (2023): 95 - 102. 10.4274/eamr.galenos.2023.69077
MLA	Saglam Yucel,bolukbasi yasemin,BINGOLBALI AYHAN,SELEK UGUR Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. European Archives of Medical Research, vol.39, no.2, 2023, ss.95 - 102. 10.4274/eamr.galenos.2023.69077
AMA	Saglam Y,bolukbasi y,BINGOLBALI A,SELEK U Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. European Archives of Medical Research. 2023; 39(2): 95 - 102. 10.4274/eamr.galenos.2023.69077
Vancouver	Saglam Y,bolukbasi y,BINGOLBALI A,SELEK U Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer. European Archives of Medical Research. 2023; 39(2): 95 - 102. 10.4274/eamr.galenos.2023.69077
IEEE	Saglam Y,bolukbasi y,BINGOLBALI A,SELEK U "Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer." European Archives of Medical Research, 39, ss.95 - 102, 2023. 10.4274/eamr.galenos.2023.69077
ISNAD	Saglam, Yucel vd. "Optimized Hybrid Arc for Improved Sparing of Organs at Risk: Balanced Combination of IMRT and VMAT in Prostate Cancer". European Archives of Medical Research 39/2 (2023), 95-102. https://doi.org/10.4274/eamr.galenos.2023.69077