Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum

Yıl: 2023 Cilt: 7 Sayı: 2 Sayfa Aralığı: 160 - 164 Metin Dili: İngilizce DOI: 10.14744/ejmo.2023.33713 İndeks Tarihi: 05-07-2023

Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum

Öz:
Objectives: Linked color imaging (LCI) helps to differentiate minor mucosal changes, which can be objectively judged by red–green–blue pixel brightness. However, whether this color analytic model based on pixel brightness can be ap- plied to diagnose Helicobacter pylori infection remains unknown. Methods: Consecutive adult patients with indications and underwent esophagogastroduodenoscopy for the 1st time were enrolled in the training (n=166) and validation (n=79) set. Demographic and clinical characteristics were recorded. Target region in gastric antrum was pictured before biopsy for rapid urea test, and pixel brightness was calculated by MATLAB software. Results: In training set, 25 patients had H. pylori infection. Pixel brightness for R and B in patients with H. pylori infection was greatly higher than those in patients without H. pylori infection (R: 210.203±27.233 vs. 196.401±29.018, p=0.043; B: 127.621±26.112 vs. 125.334±27.812, p=0.025). At the cut off of R = 210 and B = 127, the specificity and sensitivity were 0.696 and 0.701. In validation set, 10 patients had H. pylori infection and the findings were consistent with those in training set. Conclusion: Color analytic model based on pixel brightness under LCI was useful in diagnosing H. pylori infection in gastric antrum.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Li H, Hou X, Lin R, Fan M, Pang S, Jiang L, et al. Advanced en- doscopic methods in gastrointestinal diseases: a systematic review. Quant Imaging Med Surg 2019;9:905–20.
  • 2. East JE, Vleugels JL, Roelandt P, Bhandari P, Bisschops R, Dekker E, et al. Advanced endoscopic imaging: European Society of Gastrointestinal Endoscopy (ESGE) Technology Review. En- doscopy 2016;48:1029–45.
  • 3. Li L, Tan J, Liu L, Li J, Chen G, Chen M, et al. Association be - tween H. pylori infection and health Outcomes: an umbrella review of systematic reviews and meta-analyses. BMJ Open 2020;10:e031951.
  • 4. Feng-Woei T, Ping-I HH. pylori infection and extra-gastroduo- denal diseases. J Biomed Sci 2018;25:65.
  • 5. Abo-Amer YE, Sabal A, Ahmed R, Hasan NFE, Refaie R, Mostafa SM, et al. Relationship between helicobacter pylori infection and nonalcoholic fatty liver disease (NAFLD) in a developing country: a cross-sectional study. Diabetes Metab Syndr Obes 2020;13:619–25
  • 6. Howden CW, Graham DY. Recent developments pertaining to H. pylori infection. Am J Gastroenterol 2021;116:1–3.
  • 7. Sun X, Bi Y, Dong T, Min M, Shen W, Xu Y, et al. Linked colour imaging benefits the endoscopic diagnosis of distal gastric diseases. Sci Rep 2017;7:5638.
  • 8. Sun X, Bi Y, Nong B, Hu DM, Sun XM, Chen HL, et al. Linked color imaging confers benefits in profiling H. pylori infection in the stomach. Endosc Int Open 2019;7:E885–92.
  • 9. Sun X, Dong T, Bi Y, Min M, Shen W, Xu Y, et al. Linked color imaging application for improving the endoscopic diagnosis accuracy: a pilot study. Sci Rep 2016;6:33473.
  • 10. Bordin DS, Voynovan IN, Andreev DN, Maev IV. Current helico- bacter pylori diagnostics. Diagnostics (Basel) 2021;11:1458.
  • 11. Alboraie M, Elhossary W, Aly OA, Abbas B, Abdelsalam L, Ghaith D, et al; special interest group; Egyptian Association for Study of Gastrointestinal Diseases and Liver (E A S G L D). Egyptian recommendations for management of Helicobacter pylori in- fection: 2018 report. Arab J Gastroenterol 2019;20:175–9.
  • 12. Abd-Elsalam S, Kobtan A, El-Kalla F, Elkhalawany W, Na- wasany SE, Saif SA, et al. A 2-week Nitazoxanide-based qua- druple treatment as a rescue therapy for Helicobacter pylori eradication: A single center experience. Medicine (Baltimore) 2016;95:e3879.
  • 13. Shehata MA, Talaat R, Soliman S, Elmesseri H, Soliman S, Abd- Elsalam S. Randomized controlled study of a novel triple ni- tazoxanide (NTZ)-containing therapeutic regimen versus the traditional regimen for eradication of Helicobacter pylori in- fection. Helicobacter 2017;22:e12395.
  • 14. Hiraoka Y, Miura Y, Osawa H, Nomoto Y, Takahashi H, Tsunoda M, et al. Appropriate color enhancement settings for blue laser imaging facilitates the diagnosis of early gastric cancer with high color contrast. J Gastric Cancer 2021;21:142–54.
  • 15. Ono S, Shimoda Y, Tanaka I, Kinowaki S, Inoue M, Ono M, et al. Optical effect of spraying l-menthol on gastric intestinal metaplasia visualized by linked color imaging. Eur J Gastroen- terol Hepatol 2021;33:358–63.
  • 16. Sakae H, Kanzaki H, Satomi T, Okanoue S, Obayashi Y, Hama- da K, et al. Linked color imaging (LCI) emphasizes the color changes in the gastric mucosa after helicobacter pylori eradi- cation. Dig Dis Sci 2022;67:2375–84.
  • 17. Lee SP, Lee J, Kae SH, Jang HJ, Koh DH, Jung JH, et al. The role of linked color imaging in endoscopic diagnosis of He - licobacter pylori associated gastritis. Scand J Gastroenterol 2020;55:1114–20.
  • 18. Ono S, Kawada K, Dohi O, Kitamura S, Koike T, Hori S, et al; LCI- FIND Trial Group. Linked color imaging focused on neoplasm detection in the upper gastrointestinal tract : a randomized trial. Ann Intern Med 2021;174:18–24.
  • 19. Sun X, Zhao L. RGB pixel brightness characteristics of linked color imaging in early gastric cancer: a pilot study. Gastroen- terol Res Pract 2020;2020:2105874.
  • 20. Ishikawa T, Matsumura T, Okimoto K, Nagashima A, Shiratori W, Kaneko T, et al. Efficacy of texture and color enhancement imaging in visualizing gastric mucosal atrophy and gastric neoplasms. Sci Rep 2021;11:6910.
  • 21. Fujiyoshi T, Miyahara R, Funasaka K, Furukawa K, Sawada T, Maeda K, et al. Utility of linked color imaging for endoscop- ic diagnosis of early gastric cancer. World J Gastroenterol 2019;25:1248–58.
  • 22. Jiang ZX, Nong B, Liang LX, Yan YD, Zhang G. Differential di- agnosis of Helicobacter pylori-associated gastritis with the linked-color imaging score. Dig Liver Dis 2019;51:1665–70.
  • 23. Wang L, Lin XC, Li HL, Yang XS, Zhang L, Li X, et al. Clinical significance and influencing factors of linked color imaging technique in real-time diagnosis of active Helicobacter pylori infection. Chin Med J (Engl) 2019;132:2395–401.
  • 24. Abadir AP, Ali MF, Karnes W, Samarasena JB. Artificial In- telligence in Gastrointestinal Endoscopy. Clin Endosc 2020;53:132–41.
APA Sun X, 马 翠, 张 雪, lu c, Yu h, zhang w, wang y, Zhu S, Liu M, Zhang H, miao x, 徐 杨 (2023). Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. , 160 - 164. 10.14744/ejmo.2023.33713
Chicago Sun Xiaotian,马 翠云,张 雪亭,lu changlu,Yu haiyan,zhang wei,wang ying,Zhu Shaoying,Liu MingLu,Zhang Huiming,miao xinfang,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. (2023): 160 - 164. 10.14744/ejmo.2023.33713
MLA Sun Xiaotian,马 翠云,张 雪亭,lu changlu,Yu haiyan,zhang wei,wang ying,Zhu Shaoying,Liu MingLu,Zhang Huiming,miao xinfang,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. , 2023, ss.160 - 164. 10.14744/ejmo.2023.33713
AMA Sun X,马 翠,张 雪,lu c,Yu h,zhang w,wang y,Zhu S,Liu M,Zhang H,miao x,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. . 2023; 160 - 164. 10.14744/ejmo.2023.33713
Vancouver Sun X,马 翠,张 雪,lu c,Yu h,zhang w,wang y,Zhu S,Liu M,Zhang H,miao x,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. . 2023; 160 - 164. 10.14744/ejmo.2023.33713
IEEE Sun X,马 翠,张 雪,lu c,Yu h,zhang w,wang y,Zhu S,Liu M,Zhang H,miao x,徐 杨 "Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum." , ss.160 - 164, 2023. 10.14744/ejmo.2023.33713
ISNAD Sun, Xiaotian vd. "Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum". (2023), 160-164. https://doi.org/10.14744/ejmo.2023.33713
APA Sun X, 马 翠, 张 雪, lu c, Yu h, zhang w, wang y, Zhu S, Liu M, Zhang H, miao x, 徐 杨 (2023). Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. Eurasian Journal of Medicine and Oncology, 7(2), 160 - 164. 10.14744/ejmo.2023.33713
Chicago Sun Xiaotian,马 翠云,张 雪亭,lu changlu,Yu haiyan,zhang wei,wang ying,Zhu Shaoying,Liu MingLu,Zhang Huiming,miao xinfang,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. Eurasian Journal of Medicine and Oncology 7, no.2 (2023): 160 - 164. 10.14744/ejmo.2023.33713
MLA Sun Xiaotian,马 翠云,张 雪亭,lu changlu,Yu haiyan,zhang wei,wang ying,Zhu Shaoying,Liu MingLu,Zhang Huiming,miao xinfang,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. Eurasian Journal of Medicine and Oncology, vol.7, no.2, 2023, ss.160 - 164. 10.14744/ejmo.2023.33713
AMA Sun X,马 翠,张 雪,lu c,Yu h,zhang w,wang y,Zhu S,Liu M,Zhang H,miao x,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. Eurasian Journal of Medicine and Oncology. 2023; 7(2): 160 - 164. 10.14744/ejmo.2023.33713
Vancouver Sun X,马 翠,张 雪,lu c,Yu h,zhang w,wang y,Zhu S,Liu M,Zhang H,miao x,徐 杨 Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum. Eurasian Journal of Medicine and Oncology. 2023; 7(2): 160 - 164. 10.14744/ejmo.2023.33713
IEEE Sun X,马 翠,张 雪,lu c,Yu h,zhang w,wang y,Zhu S,Liu M,Zhang H,miao x,徐 杨 "Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum." Eurasian Journal of Medicine and Oncology, 7, ss.160 - 164, 2023. 10.14744/ejmo.2023.33713
ISNAD Sun, Xiaotian vd. "Linked Color Imaging and Color Analytic Model Based on Pixel Brightness for Diagnosing H. Pylori Infection in Gastric Antrum". Eurasian Journal of Medicine and Oncology 7/2 (2023), 160-164. https://doi.org/10.14744/ejmo.2023.33713