Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients

Demir, Metin

doi:10.14744/ejmi.2023.71229

Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients

Metin DEMİR (Erzurum Bölge Eğitim ve Araştırma Hastanesi, Tıbbi Onkoloji Anabilim Dalı, Erzurum, Türkiye)

Eurasian Journal of Medical Investigation

5 0

Yıl: 2023 Cilt: 7 Sayı: 2 Sayfa Aralığı: 162 - 169 Metin Dili: İngilizce DOI: 10.14744/ejmi.2023.71229 İndeks Tarihi: 07-07-2023

Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients

Öz:

Objectives: Non-metastatic esophageal squamous cell carcinoma (ESCC) patients are treated with neoadjuvant chemoradiotherapy (CRT) followed by surgery. Older patients may have treatment-related toxicity at higher rates. We presented our experience regarding CRT followed by surgery on survival in older ESCC patients. Methods: Older ESCC patients diagnosed between 2009-2021 were included. Overall survival (OS) estimates were cal- culated by Kaplan-Meier analyses and compared by Log-rank tests. Effects of ECOG performance status and age groups on survival were also presented. Results: A total of 66 older ESCC patients were included. The median duration of follow-up was 62.3 months. The me- dian OS of patients who were treated with surgery was significantly higher than those who were treated with CRT alone (48+, CI 95%: - vs. 14.1 months, CI 95%: 9.3-18.8, respectively, p=0.005). The median OS of patients who underwent sur- gery was significantly higher after adjusting by ECOG performance status and age groups than those who were treated with CRT alone (adjusted p=0.008 for ECOG and adjusted p=0.011 for age groups at diagnosis). Conclusion: Surgery after CRT improves survival in older ESCC patients compared to CRT alone. Therefore, surgery should not be avoided in older patients solely due to patient age.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	Demir M (2023). Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. , 162 - 169. 10.14744/ejmi.2023.71229
Chicago	Demir Metin Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. (2023): 162 - 169. 10.14744/ejmi.2023.71229
MLA	Demir Metin Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. , 2023, ss.162 - 169. 10.14744/ejmi.2023.71229
AMA	Demir M Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. . 2023; 162 - 169. 10.14744/ejmi.2023.71229
Vancouver	Demir M Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. . 2023; 162 - 169. 10.14744/ejmi.2023.71229
IEEE	Demir M "Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients." , ss.162 - 169, 2023. 10.14744/ejmi.2023.71229
ISNAD	Demir, Metin. "Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients". (2023), 162-169. https://doi.org/10.14744/ejmi.2023.71229

APA	Demir M (2023). Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. Eurasian Journal of Medical Investigation, 7(2), 162 - 169. 10.14744/ejmi.2023.71229
Chicago	Demir Metin Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. Eurasian Journal of Medical Investigation 7, no.2 (2023): 162 - 169. 10.14744/ejmi.2023.71229
MLA	Demir Metin Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. Eurasian Journal of Medical Investigation, vol.7, no.2, 2023, ss.162 - 169. 10.14744/ejmi.2023.71229
AMA	Demir M Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. Eurasian Journal of Medical Investigation. 2023; 7(2): 162 - 169. 10.14744/ejmi.2023.71229
Vancouver	Demir M Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients. Eurasian Journal of Medical Investigation. 2023; 7(2): 162 - 169. 10.14744/ejmi.2023.71229
IEEE	Demir M "Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients." Eurasian Journal of Medical Investigation, 7, ss.162 - 169, 2023. 10.14744/ejmi.2023.71229
ISNAD	Demir, Metin. "Surgery: The Fundamental Part of Treatment in Elderly Esophageal Squamous Cell Carcinoma Patients". Eurasian Journal of Medical Investigation 7/2 (2023), 162-169. https://doi.org/10.14744/ejmi.2023.71229