TY  - JOUR
TI  - Relationship of muscle thickness, strength, and diaphragm function in adults with cystic fibrosis
AB  - Objectives: This study aimed to evaluate the muscle thickness, strength, and diaphragmatic function and relate them with clinical findings. Patients and methods: The cross-sectional study was conducted with 54 participants (27 males, 27 females; mean age; 24.5±5.3 years; range, 18 to 45 years) between January 2017 and October 2017. Of the participants, 31 were adult CF patients, and 23 were age-and sex-matched controls. Patient demographics, 6-min walk distance, body mass index (BMI), and fat-free mass index (FFMI) were evaluated. Each patient underwent pulmonary function tests. Quadriceps femoris thickness and diaphragm thickening fraction were assessed by ultrasonography. Upper extremity strength was measured with a handheld dynamometer. Results: There was no difference between the patients’ and controls’ BMI (p=0.052). However, patients’ FFMI was lower than the controls’ (p=0.010). The FFMI correlated with pulmonary function tests. Patients’ both right and left quadriceps femoris muscles were thinner than the controls (p=0.001 and p=0.001, respectively). Patients with pancreatic insufficiency had thinner muscles than patients without pancreatic insufficiency. The control group had a stronger handgrip than CF patients (33.5±10.1 vs. 24.5±9.2 kg, p=0.003). Conclusion: Peripheral muscle wasting and weakness and lower functional capacity are highly prevalent in CF patients.
AU  - Kocakaya, Derya
AU  - OLGUN, Sehnaz
AU  - Eryüksel, Semiha Emel
AU  - Ceyhan, Berrin
AU  - Karaketir, Şeyma
AU  - Uslu, Nazlı Zeynep
AU  - Kenis-Coskun, Ozge
AU  - cimsit, canan
DO  - 10.5606/tftrd.2023.10361
PY  - 2023
JO  - Turkish Journal of Physical Medicine and Rehabilitation
VL  - 69
IS  - 2
SN  - 2587-0823
SP  - 200
EP  - 206
DB  - TRDizin
UR  - http://search/yayin/detay/1185419
ER  -