TY  - JOUR
TI  - First report of qnr and blaVIM-4-like producing clinical Alcaligenes faecalis isolated in Türkiye
AB  - The study set out to look at the clinical strain of A. faecalis's antibiotic susceptibility pattern. Both biochemical and molecular approaches were used to identify A.faecalis. The VITEK compact system was used to analyze the strain's antibiotic susceptibility profile. The use of PCR was evaluated to determine the presence of resistance genes. It was also determined whether resistance determinants could be transferred. It was determined that A. feacalis showed resistance to imipenem, cefepime, ceftazidime, gentamicin, amikacin, netilmicin, tobramicin, ciprofloxacin, and levofloxacin. The blaVIM-4-like gene was present in this strain, according to the results of the PCR and DNA sequencing studies. In contrast to VIM-4, this blaVIM-4-like gene showed one amino acid change (Ala265Val).Filter-mating experiments showed that the blaVIM-4-like gene cannot be transferred from A. faecalis to E. coli. In this study, This research, demonstrated the presence of the blaVIM-4-like gene for the first time in A. faecalis from Turkey.
AU  - Köse, Tuba
AU  - undefined, Mikail
AU  - BERIS, FATIH SABAN
AU  - ÖZAD DÜZGÜN, AZER
AU  - akyildiz, esma
AU  - SARAL SARIYER, AYSEGÜL
DO  - 10.17714/gumusfenbil.1179361
PY  - 2023
JO  - Gümüşhane Üniversitesi Fen Bilimleri Dergisi
VL  - 13
IS  - 1
SN  - 2146-538X
SP  - 57
EP  - 65
DB  - TRDizin
UR  - http://search/yayin/detay/1187356
ER  -