Yıl: 2023 Cilt: 55 Sayı: 2 Sayfa Aralığı: 114 - 119 Metin Dili: İngilizce DOI: 10.5152/eurasianjmed.2023.0060 İndeks Tarihi: 20-07-2023

Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?

Öz:
Objective: Surgical excisional biopsy is accepted as the standard of care approach in the diagnosis of lympho mas. Financial issues related to the increased cost and the invasive nature of the procedure forced physicians to use some alternative diagnostic methods. Percutaneous core needle biopsy, which gained a reputation for the diagnosis of lymphomas with the advent of improved pathological, immunohistochemical, and molecular analysis, made it possible to have an accurate diagnosis with limited tissue samples. In this retrospective study, we aimed to compare the diagnostic yield of surgical excisional biopsy and core needle biopsy. Materials and Methods: This study included 131 patients who were diagnosed with lymphoma with a nodal biopsy which was acquired via surgical excisional biopsy or core needle biopsy between 2014 and 2020 in our center. Around 68 patients underwent surgical excisional biopsy and the remaining 63 underwent core needle biopsy. Samples that allowed to the identification of the exact tumor type and/or subtype were accepted as fully diagnostic. Sufficient amount of tissue that the pathologist could have any suspicious findings considering malignant lymphoma was classified as partial diagnostic group. Inadequate samples were the ones who were not enough to report any final diagnosis. Results: The patients who underwent a core needle biopsy were significantly older than the patients who underwent to surgical excisional biopsy (56.8 vs. 47.6, P=.003). Despite the full diagnostic ability of surgical excisional biopsy outperformed core needle biopsy (95.2 % vs. 83.8 %, P=.035), in 92.6% of the patients whose tissue samples were obtained via core needle biopsy were accepted to have a sufficient diagnosis to initiate the treatment and not required a second biopsy, which was comparable with the ones achieved by surgical excisional biopsy (92.6% vs. 95.2%, P=.720). Conclusion: According to the results obtained in our study, we may conclude that core needle biopsy is a viable and comparable alternative to surgical excisional biopsy, offering a less invasive and less-expansive approach.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
0
0
0
  • 1. Swerdlow SH, Campo E, Harris N, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed. WHO; 2017;2.
  • 2. Thomas JO, Adeyi D, Amanguno H. Fine-needle aspiration in the management of peripheral lym phadenopathy in a developing country. Diagn Cytopathol. 1999;21(3):159-162. [CrossRef]
  • 3. Frederiksen JK, Sharma M, Casulo C, Burack WR. Systematic review of the effectiveness of fine needle aspiration and/or core needle biopsy for subclassifying lymphoma. Arch Pathol Lab Med. 2015;139(2):245-251. [CrossRef]
  • 4. Eichenauer DA, Aleman BMP, André M, et al. Hodgkin lymphoma: ESMO Clinical Practice Guide lines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29(suppl 4):iv19-iv29. [CrossRef]
  • 5. Dreyling M, Campo E, Hermine O, et al. Newly diagnosed and relapsed mantle cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017;28 (suppl_4):iv62-iv71. [CrossRef]
  • 6. Dreyling M, Ghielmini M, Rule S, et al. Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017;28(12):3109. [CrossRef]
  • 7. Burke C, Thomas R, Inglis C, et al. Ultrasound guided core biopsy in the diagnosis of lymphoma of the head and neck. A 9 year experience. Br J Radiol. 2011;84(1004):727-732. [CrossRef]
  • 8. de Kerviler E, de Bazelaire C, Mounier N, et al. Image-guided core-needle biopsy of peripheral lymph nodes allows the diagnosis of lymphomas. Eur Radiol. 2007;17(3):843-849. [CrossRef]
  • 9. Wilczynski A, Görg C, Timmesfeld N, et al. Value and diagnostic accuracy of ultrasound-guided full core needle biopsy in the diagnosis of lymphad enopathy: a retrospective evaluation of 793 cases. J Ultrasound Med. 2020;39(3):559-567. [CrossRef]
  • 10. Ben-Yehuda D, Polliack A, Okon E, et al. Image guided core-needle biopsy in malignant lym phoma: experience with 100 patients that suggests the technique is reliable. J Clin Oncol. 1996;14(9):2431-2434. [CrossRef]
  • 11. Seviar D, Yousuff M, Chia Z, Ramesar K, New man J, Howlett DC. Image-guided core needle biopsy as the first-line diagnostic approach in lymphoproliferative disorders-A review of the current literature. Eur J Haematol. 2021;106(2):139-147. [CrossRef]
  • 12. Johl A, Lengfelder E, Hiddemann W, Klap per W, German Low-grade Lymphoma Study Group (GLSG). Core needle biopsies and surgi cal excision biopsies in the diagnosis of lymphoma-experience at the lymph node Reg istry Kiel. Ann Hematol. 2016;95(8):1281-1286. [CrossRef]
  • 13. Assaf N, Nassif S, Tamim H, Bazarbachi A, Zaatari G, Chakhachiro Z. Diagnosing lym phoproliferative disorders using core needle biopsy versus surgical excisional biopsy: three year experience of a reference center in Leba non. Clin Lymphoma Myeloma Leuk. 2020;20(8):e455-e460. [CrossRef]
  • 14. Skelton E, Jewison A, Okpaluba C, et al. Image guided core needle biopsy in the diagnosis of malignant lymphoma. Eur J Surg Oncol. 2015;41(7):852-858. [CrossRef]
  • 15. Li L, Wu QL, Liu LZ, et al. Value of CT-guided core-needle biopsy in diagnosis and classification of malignant lymphomas using automated biopsy gun. World J Gastroenterol. 2005;11(31):4843- 4847. [CrossRef]
  • 16. Sklair-Levy M, Amir G, Spectre G, et al. Image guided cutting-edge-needle biopsy of peripheral lymph nodes and superficial masses for the diag nosis of lymphoma. J Comput Assist Tomogr. 2005;29(3):369-372. [CrossRef]
  • 17. Allin D, David S, Jacob A, Mir N, Giles A, Gib bins N. Use of core biopsy in diagnosing cervical lymphadenopathy: a viable alternative to surgical excisional biopsy of lymph nodes? Ann R Coll Surg Engl. 2017;99(3):242-244. [CrossRef]
  • 18. Groneck L, Quaas A, Hallek M, Zander T, Weihrauch MR. Ultrasound-guided core needle biopsies for workup of lymphadenopathy and lymphoma. Eur J Haematol. 2016;97(4):379-386. [CrossRef]
  • 19. Kiliçarslan A, Doğan M, Süngü N, et al. Can cutting-needle biopsy be an alternative to exci sional biopsy in lymph node pathologies? Turk Patoloji Derg. 2017;1(1):235-239. [CrossRef]
APA mutlu Y, balik aydin b, Cakir A, canöz ö, Erol C, Sevindik O (2023). Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. , 114 - 119. 10.5152/eurasianjmed.2023.0060
Chicago mutlu Yaşa gül,balik aydin berrin,Cakir Asli,canöz özlem,Erol Cengiz,Sevindik Omur Gokmen Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. (2023): 114 - 119. 10.5152/eurasianjmed.2023.0060
MLA mutlu Yaşa gül,balik aydin berrin,Cakir Asli,canöz özlem,Erol Cengiz,Sevindik Omur Gokmen Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. , 2023, ss.114 - 119. 10.5152/eurasianjmed.2023.0060
AMA mutlu Y,balik aydin b,Cakir A,canöz ö,Erol C,Sevindik O Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. . 2023; 114 - 119. 10.5152/eurasianjmed.2023.0060
Vancouver mutlu Y,balik aydin b,Cakir A,canöz ö,Erol C,Sevindik O Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. . 2023; 114 - 119. 10.5152/eurasianjmed.2023.0060
IEEE mutlu Y,balik aydin b,Cakir A,canöz ö,Erol C,Sevindik O "Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?." , ss.114 - 119, 2023. 10.5152/eurasianjmed.2023.0060
ISNAD mutlu, Yaşa gül vd. "Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?". (2023), 114-119. https://doi.org/10.5152/eurasianjmed.2023.0060
APA mutlu Y, balik aydin b, Cakir A, canöz ö, Erol C, Sevindik O (2023). Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. Eurasian Journal of Medicine, 55(2), 114 - 119. 10.5152/eurasianjmed.2023.0060
Chicago mutlu Yaşa gül,balik aydin berrin,Cakir Asli,canöz özlem,Erol Cengiz,Sevindik Omur Gokmen Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. Eurasian Journal of Medicine 55, no.2 (2023): 114 - 119. 10.5152/eurasianjmed.2023.0060
MLA mutlu Yaşa gül,balik aydin berrin,Cakir Asli,canöz özlem,Erol Cengiz,Sevindik Omur Gokmen Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. Eurasian Journal of Medicine, vol.55, no.2, 2023, ss.114 - 119. 10.5152/eurasianjmed.2023.0060
AMA mutlu Y,balik aydin b,Cakir A,canöz ö,Erol C,Sevindik O Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. Eurasian Journal of Medicine. 2023; 55(2): 114 - 119. 10.5152/eurasianjmed.2023.0060
Vancouver mutlu Y,balik aydin b,Cakir A,canöz ö,Erol C,Sevindik O Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?. Eurasian Journal of Medicine. 2023; 55(2): 114 - 119. 10.5152/eurasianjmed.2023.0060
IEEE mutlu Y,balik aydin b,Cakir A,canöz ö,Erol C,Sevindik O "Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?." Eurasian Journal of Medicine, 55, ss.114 - 119, 2023. 10.5152/eurasianjmed.2023.0060
ISNAD mutlu, Yaşa gül vd. "Should Core Needle Lymph Node Biopsy be a Relevant Alternative to Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?". Eurasian Journal of Medicine 55/2 (2023), 114-119. https://doi.org/10.5152/eurasianjmed.2023.0060