TY  - JOUR
TI  - Should Core Needle Lymph Node Biopsy be a Relevant Alternative to  Surgical Excisional Biopsy in Diagnostic Work Up of Lymphomas?
AB  - Objective: Surgical excisional biopsy is accepted as the standard of care approach in the diagnosis of lympho mas. Financial issues related to the increased cost and the invasive nature of the procedure forced physicians  to use some alternative diagnostic methods. Percutaneous core needle biopsy, which gained a reputation for  the diagnosis of lymphomas with the advent of improved pathological, immunohistochemical, and molecular  analysis, made it possible to have an accurate diagnosis with limited tissue samples. In this retrospective study,  we aimed to compare the diagnostic yield of surgical excisional biopsy and core needle biopsy. Materials and Methods: This study included 131 patients who were diagnosed with lymphoma with a nodal  biopsy which was acquired via surgical excisional biopsy or core needle biopsy between 2014 and 2020 in  our center. Around 68 patients underwent surgical excisional biopsy and the remaining 63 underwent core  needle biopsy. Samples that allowed to the identification of the exact tumor type and/or subtype were  accepted as fully diagnostic. Sufficient amount of tissue that the pathologist could have any suspicious findings  considering malignant lymphoma was classified as partial diagnostic group. Inadequate samples were the ones  who were not enough to report any final diagnosis.  Results: The patients who underwent a core needle biopsy were significantly older than the patients who  underwent to surgical excisional biopsy (56.8 vs. 47.6, P=.003). Despite the full diagnostic ability of surgical  excisional biopsy outperformed core needle biopsy (95.2 % vs. 83.8 %, P=.035), in 92.6% of the patients  whose tissue samples were obtained via core needle biopsy were accepted to have a sufficient diagnosis to  initiate the treatment and not required a second biopsy, which was comparable with the ones achieved by  surgical excisional biopsy (92.6% vs. 95.2%, P=.720).  Conclusion: According to the results obtained in our study, we may conclude that core needle biopsy is a  viable and comparable alternative to surgical excisional biopsy, offering a less invasive and less-expansive  approach.
AU  - mutlu, Yaşa gül
AU  - canöz, özlem
AU  - Erol, Cengiz
AU  - balik aydin, berrin
AU  - Sevindik, Omur Gokmen
AU  - Cakir, Asli
DO  - 10.5152/eurasianjmed.2023.0060
PY  - 2023
JO  - Eurasian Journal of Medicine
VL  - 55
IS  - 2
SN  - 1308-8734
SP  - 114
EP  - 119
DB  - TRDizin
UR  - http://search/yayin/detay/1188005
ER  -