Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows
Yıl: 2023 Cilt: 16 Sayı: 2 Sayfa Aralığı: 143 - 159 Metin Dili: İngilizce DOI: 10.30607/kvj.1151028 İndeks Tarihi: 20-07-2023
Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows
Öz: The transition period in dairy cows is generally accepted as the period covering 3 weeks before calving and 3 weeks after calving. The aim of the study was to compare the profiles of β-hydroxybutyrate, calcium, magnesium, phosphorus, total cholesterol, total protein, triacylglycerol, free glycerol, serum lipid and serum protein with Anti-Mullerian Hormone (AMH) in dairy cows in the transition period, and to determine whether AMH to examine whether it can be used as a marker in the next insemination period. The cows whose blood samples were taken were followed up and it was determined that they became pregnant at the insemination and the study was terminated. According to the results obtained; It was determined that BHB and free glycerol, which are important markers of negative energy balance (NEB), have an effect on AMH concentration. However, it was determined that the concentration of magnesium and the ratio of cholesterol ester in serum total fat did not change much during the transition period. Our results suggest that AMH is a good biomarker of decreased follicular activity due to NEB in the transition period and that AMH can be used for herd weeding in reinsemination.
Anahtar Kelime: İneklerde Geçiş Döneminde Anti-Müllerian Hormon, Metabolik Profil ve Mineral Düzeylerinin Buzağılama – Gebelik Aralığına Etkisi
Öz: Sütçü ineklerde geçiş dönemi genel kabul ile buzağılamadan önceki 3 hafta ile buzağılamadan sonraki 3 haftatı kapsayan süreçtir. Bu çalışmanın amacı geçiş dönemindeki sütçü ineklerde negaif eneji dengesinden (NED) dolayı değişen β-hidroksibütirat, kalsiyum, magnezyum, fosfor, total kolesterol, total protein, triaçilgliserol, serbest gliserol, serum lipid ve serum protein profillerinin Anti-Müllerian Hormon (AMH) ile karşılaştırılarak AMH’nin bir sonraki tohumlama döneminde belirteç olarak kullanılıp lullanılmayacağını incelemektir. Kan örnekleri alınan inekler daha sonra takip edilerek kaçıncı tohumlamada gebe kaldıkları tespit edildi ve çalışma sonlandırıldı. Santrifüj edilerek serumları toplanan kanlar analiz edildi. Elde edilen sonuçlara göre; NED’in önemli belirteçlerinden BHB’nin ve serbest gliserolün AMH konsantrasyonu üzerine etkisi olduğu saptandı. Bununla birlikte, magnezyumun konsantrasyonunun ve serum toplam yağı içerisindeki kolesterol esteri oranının geçiş döneminde fazla değişmediği tespit edildi. Sonuçlarımız AMH’nin geçiş döneminde NED’den dolayı azalan folliküler aktivitenin iyi bir biyobelirteci olduğunu ve tekrar tohumlamada AMH’nin sürü ayıklama için kullanılabileceğini göstermektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Adewuyi, A. A., Gruys, E., & Van Eerdenburg, F. J. C. M. (2005). Non esterified fatty acids (NEFA) in dairy cattle. A review. Veterinary quarterly, 27(3), 117-126. https://doi.org/10.1080/01652176.2005.9695192
- Batista, E. O. S., Macedo, G. G., Sala, R. V., Ortolan, M. D. D. V., Sá Filho, M. F. D., Del Valle, T. A., ... &
- Baruselli, P. S. (2014). Plasma antimullerian hormone as a predictor of ovarian antral follicular population in Bos indicus (Nelore) and Bos taurus (Holstein) heifers. Reproduction in Domestic Animals, 49(3), 448-452. https://doi.org/10.1111/rda.12304
- Bell, A. W. (1995). Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. Journal of animal science, 73(9), 2804-2819. https://doi.org/10.2527/1995.7392804x
- Cengiz, M., Kaynar, O., Cannazik, O., Ileriturk, M., Cengiz, S., & Hayirli, A. (2015). Sampling factors causing variability in milk constituents in early lactation cows. Vet. Med-Czech, 60, 6-15. https://doi.org/10.17221/7920-VETMED
- Djoković, R., Cincović, M., Belić, B., Toholj, B., Davidov, I., & Hristovska, T. (2015). Relationship between blood metabolic hormones, metabolites and energy balance in Simmental dairy cows during peripartum period and lactation. Pak. Vet. J, 35(2), 163-167.
- Drackley, J. K. (1999). Biology of dairy cows during the transition period: The final frontier?. Journal of dairy science, 82(11), 2259-2273. https://doi.org/10.3168/jds.S0022-0302(99)75474-3
- Drackley, J. K., Dann, H. M., Douglas, N., Guretzky, N. A. J., Litherland, N. B., Underwood, J. P., & Loor, J. J. (2005). Physiological and pathological adaptations in dairy cows that may increase susceptibility to periparturient diseases and disorders. Italian Journal of Animal Science, 4(4), 323-344. https://doi.org/10.4081/ijas.2005.323
- Van der Drift, S. G. A., Houweling, M., Schonewille, J. T., Tielens, A. G. M., & Jorritsma, R. (2012). Protein and fat mobilization and associations with serum β- hydroxybutyrate concentrations in dairy cows. Journal of dairy science, 95(9), 4911-4920. https://doi.org/10.3168/jds.2011-4771
- Duffield, T. (2000). Subclinical ketosis in lactating dairy cattle. Veterinary clinics of north america: Food animal practice, 16(2), 231-253. https://doi.org/10.1016/S0749-0720(15)30103-1
- Eicker, S. W., Gröhn, Y. T., & Hertl, J. A. (1996). The association between cumulative milk yield, days open, and days to first breeding in New York Holstein cows. Journal of Dairy Science, 79(2), 235-241. https://doi.org/10.3168/jds.S0022-0302(96)76356-7
- Campos Gaona, R., García Alegría, K., Hernández, E. A., & Giraldo Patiño, L. (2012). Protein and mineral metabolites for dairy cows during the transition period under tropical conditions. Revista Facultad Nacional de Agronomía Medellín, 65(2), 6719-6728.
- Gobikrushanth, M., Dutra, P. A., Bruinje, T. C., Colazo, M. G., Butler, S. T., & Ambrose, D. J. (2017). Repeatability of antral follicle counts and anti-Müllerian hormone and their associations determined at an unknown stage of follicular growth and an expected day of follicular wave emergence in dairy cows. Theriogenology, 92, 90-94. https://doi.org/10.1016/j.theriogenology.2017.01.018
- Gobikrushanth, M., Purfield, D. C., Colazo, M. G., Butler, S. T., Wang, Z., & Ambrose, D. J. (2018). The relationship between serum anti-Müllerian hormone concentrations and fertility, and genome-wide associations for anti- Müllerian hormone in Holstein cows. Journal of dairy science, 101(8), 7563-7574. https://doi.org/10.3168/jds.2017-13940
- Goff, J. P. (2006). Macromineral physiology and application to the feeding of the dairy cow for prevention of milk fever and other periparturient mineral disorders. Animal feed science and technology, 126(3-4), 237-257. https://doi.org/10.1016/j.anifeedsci.2005.08.005
- Goff, J. P., & Horst, R. L. (1997). Physiological changes at parturition and their relationship to metabolic disorders. Journal of dairy science, 80(7), 1260-1268. https://doi.org/10.3168/jds.S0022-0302(97)76055-7
- Gross, J. J., Kessler, E. C., Albrecht, C., & Bruckmaier, R. M. (2015). Response of the cholesterol metabolism to a negative energy balance in dairy cows depends on the lactational stage. PloS one, 10(6), e0121956. https://doi.org/10.1371/journal.pone.0121956
- Grummer, R. R. (1995). Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. Journal of animal science, 73(9), 2820-2833. https://doi.org/10.2527/1995.7392820x
- Grummer, R. R., Mashek, D. G., & Hayirli, A. (2004). Dry matter intake and energy balance in the transition period. Veterinary Clinics: Food Animal Practice, 20(3), 447-470. https://doi.org/10.1016/j.cvfa.2004.06.013
- Grünberg, W. (2014). Treatment of phosphorus balance disorders. Veterinary Clinics: Food Animal Practice, 30(2), 383-408. https://doi.org/10.1016/j.cvfa.2014.03.002
- Ingvartsen, K. L. (2006). Feeding-and management-related diseases in the transition cow: Physiological adaptations around calving and strategies to reduce feeding-related diseases. Animal feed science and technology, 126(3-4), 175-213. https://doi.org/10.1016/j.anifeedsci.2005.08.003
- Ireland, J. J., Smith, G. W., Scheetz, D., Jimenez-Krassel, F., Folger, J. K., Ireland, J. L. H., ... & Evans, A. C. O. (2010). Does size matter in females? An overview of the impact of the high variation in the ovarian reserve on ovarian function and fertility, utility of anti-Müllerian hormone as a diagnostic marker for fertility and causes of variation in the ovarian reserve in cattle. Reproduction, Fertility and Development, 23(1), 1-14. https://doi.org/10.1071/RD10226
- Ireland, J. J., Ward, F., Jimenez-Krassel, F., Ireland, J. L. H., Smith, G. W., Lonergan, P., & Evans, A. C. O. (2007). Follicle numbers are highly repeatable within individual animals but are inversely correlated with FSH concentrations and the proportion of good-quality embryos after ovarian stimulation in cattle. Human Reproduction, 22(6), 1687-1695. https://doi.org/10.1093/humrep/dem071
- Ireland, J. L. H., Scheetz, D., Jimenez-Krassel, F., Themmen, A. P. N., Ward, F., Lonergan, P., ... & Ireland, J. J. (2008). Antral follicle count reliably predicts number of morphologically healthy oocytes and follicles in ovaries of young adult cattle. Biology of reproduction, 79(6), 1219- 1225. https://doi.org/10.1095/biolreprod.108.071670
- Kaneko, J. J., Harvey, J. W., & Bruss, M. L. (2008). Clinical biochemistry of domestic animals. 6th edition. Academic Press.
- Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. nature, 227(5259), 680-685. https://doi.org/10.1038/227680a0
- LeBlanc, S. (2010). Monitoring metabolic health of dairy cattle in the transition period. Journal of reproduction and Development, 56(S), S29-S35. https://doi.org/10.1262/jrd.1056S29
- Li, Y., Ding, H. Y., Wang, X. C., Feng, S. B., Li, X. B., Wang, Z., ... & Li, X. W. (2016). An association between the level of oxidative stress and the concentrations of NEFA and BHBA in the plasma of ketotic dairy cows. Journal of animal physiology and animal nutrition, 100(5), 844-851. https://doi.org/10.1111/jpn.12454
- Macrae, A. I., Whitaker, D. A., Burrough, E., Dowell, A., & Kelly, J. M. (2006). Use of metabolic profiles for the assessment of dietary adequacy in UK dairy herds. Veterinary Record, 159(20), 655-661. https://doi.org/10.1136/vr.159.20.655
- La Marca, A., Broekmans, F. J., Volpe, A., Fauser, B. C., & Macklon, N. S. (2009). Anti-Müllerian hormone (AMH): what do we still need to know?. Human reproduction, 24(9), 2264-2275. https://doi.org/10.1093/humrep/dep210
- La Marca, A., Sighinolfi, G., Radi, D., Argento, C., Baraldi, E., Artenisio, A. C., ... & Volpe, A. (2010). Anti- Müllerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART). Human reproduction update, 16(2), 113-130. https://doi.org/10.1093/humupd/dmp036
- Ménard, L., & Thompson, A. (2007). Milk fever and alert downer cows: Does hypophosphatemia affect the treatment response?. The Canadian Veterinary Journal, 48(5), 487.
- Montagner, P., Krause, A. R. T., Schwegler, E., Weschenfelder, M. M., Rabassa, V. R., Schneider, A., ... & Corrêa, M. N. (2016). Reduction of liver function delays resumption of postpartum ovarian activity and alters the synthesis of acute phase proteins in dairy cows. Research in Veterinary Science, 106, 84-88. https://doi.org/10.1016/j.rvsc.2016.02.015
- Mossa, F., Carter, F., Walsh, S. W., Kenny, D. A., Smith, G. W., Ireland, J. L., ... & Evans, A. C. (2013). Maternal undernutrition in cows impairs ovarian and cardiovascular systems in their offspring. Biology of Reproduction, 88(4), 92-1. https://doi.org/10.1095/biolreprod.112.107235
- Pereira, F. T. V., Oliveira, L. J., Barreto, R. D. S. N., Mess, A., Perecin, F., Bressan, F. F., ... & Meirelles, F. V. (2013). Fetal-maternal interactions in the synepitheliochorial placenta using the eGFP cloned cattle model. PLoS One, 8(5), e64399. https://doi.org/10.1371/journal.pone.0064399
- Putman, A. K., Brown, J. L., Gandy, J. C., Wisnieski, L., & Sordillo, L. M. (2018). Changes in biomarkers of nutrient metabolism, inflammation, and oxidative stress in dairy cows during the transition into the early dry period. Journal of dairy science, 101(10), 9350-9359. https://doi.org/10.3168/jds.2018-14591
- Ribeiro, E. S., Bisinotto, R. S., Lima, F. S., Greco, L. F., Morrison, A., Kumar, A., ... & Santos, J. E. P. (2014). Plasma anti-Müllerian hormone in adult dairy cows and associations with fertility. Journal of Dairy Science, 97(11), 6888-6900. https://doi.org/10.3168/jds.2014-7908
- Rico, C., Fabre, S., Médigue, C., Clemente, N. D., Clément, F., Bontoux, M., ... & Monniaux, D. (2009). Anti- Müllerian hormone is an endocrine marker of ovarian gonadotropin-responsive follicles and can help to predict superovulatory responses in the cow. Biology of reproduction, 80(1), 50-59. https://doi.org/10.1095/biolreprod.108.072157
- Risco, C. A., Drost, M., Thatcher, W. W., Savio, J., & Thatcher, M. J. (1994). Effects of calving-related disorders on prostaglandin, calcium, ovarian activity and uterine involution in postrartum dairy cows. Theriogenology, 42(1), 183-203. https://doi.org/10.1016/0093-691X(94)90675-9
- Van Saun, R. J. (2016). Indikatoren für Risiken bei Kühen in der Transitphase–eine Übersicht zu metabolischen Profilen. Tierärztliche Praxis Ausgabe G: Großtiere/Nutztiere, 44(02), 118-126. https://doi.org/10.15653/TPG-150947
- Souza, A. H., Carvalho, P. D., Rozner, A. E., Vieira, L. M., Hackbart, K. S., Bender, R. W., ... & Wiltbank, M. C. (2015). Relationship between circulating anti-Müllerian hormone (AMH) and superovulatory response of high- producing dairy cows. Journal of dairy science, 98(1), 169- 178. https://doi.org/10.3168/jds.2014-8182
- Trevisi, E., Jahan, N., Bertoni, G., Ferrari, A., & Minuti, A. (2015). Pro-inflammatory cytokine profile in dairy cows: consequences for new lactation. Italian Journal of Animal Science, 14(3), 3862. https://doi.org/10.4081/ijas.2015.3862
- Tsioulpas, A., Grandison, A. S., & Lewis, M. J. (2007). Changes in physical properties of bovine milk from the colostrum period to early lactation. Journal of dairy science, 90(11), 5012-5017. https://doi.org/10.3168/jds.2007-0192
- Turk, R., Juretic, D., Geres, D., Turk, N., Rekic, B., Simeon- Rudolf, V., & Svetina, A. (2004). Serum paraoxonase activity and lipid parameters in the early postpartum period of dairy cows. Research in Veterinary Science, 76(1), 57- 61. https://doi.org/10.1016/j.rvsc.2003.08.001
- Wang, J., Dicken, C., Lustbader, J. W., & Tortoriello, D. V. (2009). Evidence for a Müllerian-inhibiting substance autocrine/paracrine system in adult human endometrium. Fertility and sterility, 91(4), 1195-1203. https://doi.org/10.1016/j.fertnstert.2008.01.028
- Wankhade, P. R., Manimaran, A., Kumaresan, A., Jeyakumar, S., Ramesha, K. P., Sejian, V., ... & Varghese, M. R. (2017). Metabolic and immunological changes in transition dairy cows: A review. Veterinary world, 10(11), 1367. https://doi.org/10.14202/vetworld.2017.1367-1377
- Whiteford, L. C., & Sheldon, I. M. (2005). Association between clinical hypocalcaemia and postpartum endometritis. The Veterinary Record, 157(7), 202-204.
| APA | ILERITURK M, Kaynar Ö (2023). Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. , 143 - 159. 10.30607/kvj.1151028 |
| Chicago | ILERITURK MUSTAFA,Kaynar Özgür Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. (2023): 143 - 159. 10.30607/kvj.1151028 |
| MLA | ILERITURK MUSTAFA,Kaynar Özgür Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. , 2023, ss.143 - 159. 10.30607/kvj.1151028 |
| AMA | ILERITURK M,Kaynar Ö Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. . 2023; 143 - 159. 10.30607/kvj.1151028 |
| Vancouver | ILERITURK M,Kaynar Ö Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. . 2023; 143 - 159. 10.30607/kvj.1151028 |
| IEEE | ILERITURK M,Kaynar Ö "Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows." , ss.143 - 159, 2023. 10.30607/kvj.1151028 |
| ISNAD | ILERITURK, MUSTAFA - Kaynar, Özgür. "Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows". (2023), 143-159. https://doi.org/10.30607/kvj.1151028 |
| APA | ILERITURK M, Kaynar Ö (2023). Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. Kocatepe Veterinary Journal, 16(2), 143 - 159. 10.30607/kvj.1151028 |
| Chicago | ILERITURK MUSTAFA,Kaynar Özgür Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. Kocatepe Veterinary Journal 16, no.2 (2023): 143 - 159. 10.30607/kvj.1151028 |
| MLA | ILERITURK MUSTAFA,Kaynar Özgür Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. Kocatepe Veterinary Journal, vol.16, no.2, 2023, ss.143 - 159. 10.30607/kvj.1151028 |
| AMA | ILERITURK M,Kaynar Ö Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. Kocatepe Veterinary Journal. 2023; 16(2): 143 - 159. 10.30607/kvj.1151028 |
| Vancouver | ILERITURK M,Kaynar Ö Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows. Kocatepe Veterinary Journal. 2023; 16(2): 143 - 159. 10.30607/kvj.1151028 |
| IEEE | ILERITURK M,Kaynar Ö "Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows." Kocatepe Veterinary Journal, 16, ss.143 - 159, 2023. 10.30607/kvj.1151028 |
| ISNAD | ILERITURK, MUSTAFA - Kaynar, Özgür. "Effect of Anti-Mullerian Hormone, Metabolic Profile and Mineral Levels at Transition Period On The Calving – Conception Interval in Cows". Kocatepe Veterinary Journal 16/2 (2023), 143-159. https://doi.org/10.30607/kvj.1151028 |
