Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research
Yıl: 2023 Cilt: 15 Sayı: 2 Sayfa Aralığı: 223 - 229 Metin Dili: İngilizce DOI: 10.5336/sportsci.2022-94239 İndeks Tarihi: 22-07-2023
Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research
Öz: Objective: The present study aims to examine investigation the -actinin-3 (ACTN3) gene polymorphism (rs1815739) and functional movement screen (FMS) values in young runners competing at the national level. Material and Methods: Forty-five young runners (29 male 64.4%, 16 female 35.6%) competing at the national level in different clubs affiliated to the Turkish Athletic Federation and training regularly at least 5 days a week voluntarily participated in the study. The DNA isolation of oral swab samples was carried out using the spin column (MN Macherey-Nagel, Germany) method. The genotyping pro- cess was performed using the real-time polymerase chain reaction method. Results: The FMS test battery was used to determine the functional capacity. According to the findings obtained, it was determined that in the FMS evaluation of the female runners, the runners with the CC genotype had a significantly higher mean score compared to the runners with the CT genotype (p<0.033) while in the male runners, the runners with the CT genotype had a significantly higher mean score compared to the runners with the TT genotype (p<0.031). However, in the FMS evaluation of the overall runners, no significant difference was found (p>0.205). Conclusion: It is thought that the FMS test battery and the ACTN3 gene polymorphism, which is among the important variables responsible for non-impact injuries, can be effective in the level of muscle damage, the type of muscle injury, the prediction of injuries and reducing the risk factors that may cause injuries.
Anahtar Kelime: Genç Koşucularda ACTN3 Gen Polimorfizmi (rs1815739) ile FMS Değerlerinin İncelenmesi: Kesitsel Araştırma
Öz: Amaç: Sunulan çalışma, ulusal düzeyde yarışan genç koşucu- larda -aktinin-3 [-actinin-3 (ACTN3)] gen polimorfizmi (rs1815739) ve fonksiyonel hareket analizi [functional movement screen (FMS)] değerlerini incelemeyi amaçlamaktad ır. Gereç ve Yöntemler: Araş- tırmaya, Türkiye Atletizm Federasyonuna ba ğlı farklı kulüplerde li- sanslı olarak ulusal düzeyde yar ışan, haftada en az 5 gün düzenli antrenman yapan 45 genç ko şucu (29’u erkek %64,4, 16’s ı kadın %35,6) gönüllü olarak katılmıştır. Ağız sürüntü örneklerinin DNA izo- lasyonu spin kolon (MN Macherey-Nagel, Almanya) yöntemi ile ger- çekleştirilmiştir. Genotipleme işlemi gerçek zamanlı polimeraz zincir reaksiyonu metodu ile gerçekleştirilmiştir. Fonksiyonel kapasitenin be- lirlenmesi için FMS test bataryası kullanılmıştır. Bulgular: Elde edilen bulgulara göre kadın koşucuların FMS değerlendirmesinde, CC geno- tipe sahip ko şucuların ortalama puan ının CT genotipe sahip ko şucu- lardan (p<0,033), erkek koşucularda ise CT genotipe sahip koşucuların ortalama puanı TT genotipe sahip koşuculardan (p<0,031) anlamlı bir şekilde daha yüksek olduğu tespit edilmiştir. Ancak toplam koşucula- rın FMS değerlendirmesinde genotipe göre anlaml ı bir farklılık tespit edilmemiştir (p>0,205). Sonuç: Darbelere bağlı olmayan yaralanma- lardan sorumlu önemli de ğişkenlerden ACTN3 gen polimorfizmi ve FMS test bataryasının, koşucularda kas hasarı düzeyine, kas yaralanma tipine, yaralanmaların önceden tahmin edilmesine ve yaralanmalara neden olabilecek risk faktörlerinin azalt ılmasına etkili olaca ğı düşü- nülmektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | BULĞAY C, Bayraktar I, Odemıs M, Yildirim D, ergun m, CERIT M, Ulucan K (2023). Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. , 223 - 229. 10.5336/sportsci.2022-94239 |
| Chicago | BULĞAY Celal,Bayraktar Işık,Odemıs Merıc,Yildirim Damla Selin,ergun mehmet ali,CERIT MESUT,Ulucan Korkut Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. (2023): 223 - 229. 10.5336/sportsci.2022-94239 |
| MLA | BULĞAY Celal,Bayraktar Işık,Odemıs Merıc,Yildirim Damla Selin,ergun mehmet ali,CERIT MESUT,Ulucan Korkut Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. , 2023, ss.223 - 229. 10.5336/sportsci.2022-94239 |
| AMA | BULĞAY C,Bayraktar I,Odemıs M,Yildirim D,ergun m,CERIT M,Ulucan K Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. . 2023; 223 - 229. 10.5336/sportsci.2022-94239 |
| Vancouver | BULĞAY C,Bayraktar I,Odemıs M,Yildirim D,ergun m,CERIT M,Ulucan K Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. . 2023; 223 - 229. 10.5336/sportsci.2022-94239 |
| IEEE | BULĞAY C,Bayraktar I,Odemıs M,Yildirim D,ergun m,CERIT M,Ulucan K "Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research." , ss.223 - 229, 2023. 10.5336/sportsci.2022-94239 |
| ISNAD | BULĞAY, Celal vd. "Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research". (2023), 223-229. https://doi.org/10.5336/sportsci.2022-94239 |
| APA | BULĞAY C, Bayraktar I, Odemıs M, Yildirim D, ergun m, CERIT M, Ulucan K (2023). Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. Türkiye Klinikleri Spor Bilimleri Dergisi, 15(2), 223 - 229. 10.5336/sportsci.2022-94239 |
| Chicago | BULĞAY Celal,Bayraktar Işık,Odemıs Merıc,Yildirim Damla Selin,ergun mehmet ali,CERIT MESUT,Ulucan Korkut Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. Türkiye Klinikleri Spor Bilimleri Dergisi 15, no.2 (2023): 223 - 229. 10.5336/sportsci.2022-94239 |
| MLA | BULĞAY Celal,Bayraktar Işık,Odemıs Merıc,Yildirim Damla Selin,ergun mehmet ali,CERIT MESUT,Ulucan Korkut Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. Türkiye Klinikleri Spor Bilimleri Dergisi, vol.15, no.2, 2023, ss.223 - 229. 10.5336/sportsci.2022-94239 |
| AMA | BULĞAY C,Bayraktar I,Odemıs M,Yildirim D,ergun m,CERIT M,Ulucan K Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. Türkiye Klinikleri Spor Bilimleri Dergisi. 2023; 15(2): 223 - 229. 10.5336/sportsci.2022-94239 |
| Vancouver | BULĞAY C,Bayraktar I,Odemıs M,Yildirim D,ergun m,CERIT M,Ulucan K Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. Türkiye Klinikleri Spor Bilimleri Dergisi. 2023; 15(2): 223 - 229. 10.5336/sportsci.2022-94239 |
| IEEE | BULĞAY C,Bayraktar I,Odemıs M,Yildirim D,ergun m,CERIT M,Ulucan K "Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research." Türkiye Klinikleri Spor Bilimleri Dergisi, 15, ss.223 - 229, 2023. 10.5336/sportsci.2022-94239 |
| ISNAD | BULĞAY, Celal vd. "Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research". Türkiye Klinikleri Spor Bilimleri Dergisi 15/2 (2023), 223-229. https://doi.org/10.5336/sportsci.2022-94239 |
