A SINGLE-CENTER, CROSS-SECTIONAL  PREVALENCE STUDY OF CERVICAL DIFFUSE  IDIOPATHIC SKELETAL HYPEROSTOSIS

erdoğan, mehmet mustafa; SEYHAN, SINAN

doi:10.29400/tjgeri.2023.345

A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS

Mehmet Mustafa ERDOĞAN, (Amasya Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Baş ve Boyun Cerrahisi, Amasya, Türkiye)

SINAN SEYHAN (Amasya Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Baş ve Boyun Cerrahisi, Amasya, Türkiye)

Türk Geriatri Dergisi

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Yıl: 2023 Cilt: 26 Sayı: 2 Sayfa Aralığı: 193 - 203 Metin Dili: İngilizce DOI: 10.29400/tjgeri.2023.345 İndeks Tarihi: 23-07-2023

A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS

Öz:

Introduction: In this study, we aimed to investigate the prevalence and characteristics of cervical diffuse idiopathic skeletal hyperostosis using computed tomography scans of the cervical vertebra. Materials and Methods: This study was performed using the Picture Archiving and Communication System of our hospital. Computed tomography images of 1744 patients were included in this study. The patients were divided into age groups by decade. The characteristics of the cervical osteophytes and intervertebral bridging were recorded. Cervical diffuse idiopathic skeletal hyperostosis was diagnosed based on the criteria described by Resnick and Niwayama. Results: The mean age of the study group was 48 years. The prevalence rate of cervical diffuse idiopathic skeletal hyperostosis was 6.3% (6.4% in males and 6.2% in females). The difference between genders was not statistically significant (p=0.908). The prevalence rates significantly increased as age increased. The prevalence rate of cervical osteophytes was 36.5% (33.9% in males and 40.6% in females). The most frequently affected level was C5-6 (16.9%), and the vertebra was C6 (30.6%). Osteophytes were localised in the midline with a rate of 75.5% and was most frequently found in the 70–79 age group (81.2%). Conclusion:In our study, we detected the prevalence rates of cervical diffuse idiopathic skeletal hyperostosis and cervical osteophytes, which were 6.3% and 36.5%, respectively. In comparison, the most frequently affected vertebra and intervertebral levels were, respectively, C6 (30.6%) and C5-6 (16.9%), and cervical osteophytes was most often formed in the midline (75.5%).

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1. Ozkiris M, Okur A, Kapusuz Z, Saydam L. Forestier’s syndrome: a rare cause of dysphagia. Kulak Burun Bogaz Ihtis Derg 2014; 24(1): 54-57. (DOI: 10.5606/ kbbihtisas.2014.53496)
2. Yoshihara H, Nadarajah V, Horowitz E. Prevalence and characteristics of thoracic diffuse idiopathic skeletal hyperostosis in 3299 black patients. Sci Rep 2021; 11(1): 1-7. (DOI: 10.1038/s41598-021-01092-x)
3. Resnick D, Niwayama G. Radiographic and patho logic features of spinal involvement in diffuse idio pathic skeletal hyperostosis (DISH). Radiology 1976; 119(3): 559-568. (DOI: 10.1148/119.3.559)
4. Afşar Sİ. Diffuse idiopathic skeletal hyperostosis: Review. Turk J Osteoporos 2015; 21: 132-136. (DOI: 10.4274/tod.07078)
5. Le HV, Wick JB, Van BW, Klineberg EO. Diffuse id iopathic skeletal hyperostosis of the spine: patho physiology, diagnosis, and management. J Am Acad Orthop Surg 2021; 29(24): 1044-1051. (DOI: 10.5435/ JAAOS-D-20-01344)
6. Zarei M, Golbakhsh M, Rostami M, Moosavi M. Dys phonia, Stridor, and Dysphagia caused by diffuse idiopathic skeletal hyperostosis: case report and re view of literature. Adv Biomed Res 2020; 9: 47. (DOI: 10.4103/abr.abr_50_20)
7. Kagotani R, Yoshida M, Muraki S, Oka H, Hashizume H, Yamada H, et al. Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study. J Bone Miner Me tab 2015; 33(2): 221-229. (DOI: 10.1007/s00774-014- 0583-9)
8. Kim BS, Moon MS, Yoon MG, Kim ST, Kim SJ, Kim MS, et al. Prevalence of diffuse idiopathic skeletal hyperostosis diagnosed by whole spine computed tomography: a Preliminary study. Clin Orthop Surg 2018; 10(1): 41-46. (DOI: 10.4055/cios.2018.10.1.41)
9. Cherfane P, Smaily H, Khalaf MG, Ghaoui N, Mel kane AE. Otolaryngologic manifestations of diffuse idiopathic skeletal hyperostosis (Forestier’s dis ease): a systematic review of the literature. Joint Bone Spine 2021; 88(6): 105218. (DOI: 10.1016/j.jb spin.2021.105218)
10. Harlianto NI, Kuperus JS, Mohamed Hoesein FAA, de Jong PA, de Ru JA, Oner FC, et al. Diffuse id iopathic skeletal hyperostosis of the cervical spine causing dysphagia and airway obstruction: an up dated systematic review. Spine J 2022; 22(9): 1490- 1503. (DOI: 10.1016/j.spinee.2022.03.002)
11. Varsak YK, Eryilmaz MA, Arbag H. Dysphagia and airway obstruction due to large cervical osteophyte in a patient with ankylosing spondylitis. J Crani ofac Surg 2014; 25(4): 1402-1403. (DOI: 10.1097/ SCS.0000000000000933)
12. Yoshimatsu Y, Tobino K, Maeda K, Kubota K, Haruta Y, Adachi H, et al. Management of airway obstruc tion due to diffuse idiopathic skeletal hyperostosis in the cervical spine: a case report and literature re view. Intern Med 2019; 58(2): 271-276. (DOI: 10.2169/ internalmedicine.1071-18)
13. Yoshioka K, Murakami H, Demura S, Kato S, Yoneza wa N, Takahashi N, et al. Surgical treatment for cervi cal diffuse idiopathic skeletal hyperostosis as a cause of dysphagia. Spine surgery and related research 2018; 2(3):197-201. (DOI: 10.22603/ssrr.2017-0045)
14. Mader R, Verlaan JJ, Buskila D. Diffuse idiopathic skeletal hyperostosis: clinical features and patho genic mechanisms. Nat Rev Rheumatol 2013; 9(12): 741-750. (DOI: 10.1038/nrrheum.2013.165)
15. Bateman M, Hapuarachchi K, Pinto C, Doyle AJ. Diffuse idiopathic skeletal hyperostosis (DISH): In creased prevalence in Pacific Islanders. J Med Im aging Radiat Oncol 2018; 62(2): 188-193. (DOI: 10.1111/1754-9485.12679)
16. Verlaan JJ, Boswijk PF, de Ru JA, Dhert WJ, Oner FC. Diffuse idiopathic skeletal hyperostosis of the cervi cal spine: an underestimated cause of dysphagia and airway obstruction. Spine J 2011; 11(11): 1058- 1067. (DOI: 10.1016/j.spinee.2011.09.014)
17. Hiyama A, Katoh H, Sakai D, Sato M, Tanaka M, Watanabe M. Prevalence of diffuse idiopathic skel etal hyperostosis (DISH) assessed with whole-spine computed tomography in 1479 subjects. BMC Mus culoskelet Disord 2018; 19(1): 1-7. (DOI: 10.1186/ s12891-018-2108-5)
18. Liang H, Liu G, Lu S, Chen S, Jiang D, Shi H, et al. Epidemiology of ossification of the spinal ligaments and associated factors in the Chinese population: a cross-sectional study of 2000 consecutive individu als. BMC Musculoskeletal Disorders 2019; 20(1): 1-12 (DOI: 10.1186/s12891-019-2569-1)
19. Hirasawa A, Wakao N, Kamiya M, Takeuchi M, Ka wanami K, Murotani K, et al. The prevalence of dif fuse idiopathic skeletal hyperostosis in Japan—the first report of measurement by CT and review of the literature. J Orthop Sci 2016; 21(3): 287-290. (DOI: 10.1016/j.jos.2016.02.001)
20. Xiong L, Zeng QY, Jinkins JR. CT and MRI character istics of ossification of the ligamenta flava in the tho racic spine. Eur Radiol 2001; 11(9): 1798-802. (DOI: 10.1007/s003300000788)
21. Ahmed O, Ramachandran K, Patel Y, Dhanapaul S, Meena J, Shetty AP, et al. Diffuse idiopath ic skeletal hyperostosis prevalence, characteris tics, and associated comorbidities: a cross-sec tional study of 1815 whole spine CT Scans. Global Spine J 2022: 21925682221136844. (DOI: 10.1177/21925682221136844)
22. Weinfeld RM, Olson PN, Maki DD, Griffiths HJ. The prevalence of diffuse idiopathic skeletal hyperosto sis (DISH) in two large American Midwest metropol itan hospital populations. Skeletal radiology 1997; 26(4): 222-225. (DOI: 10.1007/s002560050225)
23. Mori K, Kasahara T, Mimura T, Nishizawa K, Nakamu ra A, Imai S. Prevalence of thoracic diffuse idiopathic skeletal hyperostosis (DISH) in Japanese: results of chest CT-based cross-sectional study. J Orthop Sci 2017; 22(1): 38-42. (DOI: 10.1016/j.jos.2016.09.003)
24. Pereira EA, Carvalho MVDd, Nascimento EAd, Kobayashi SBT, Petraki GGP, Soriano EP. Diffuse idiopathic hyperostosis in human skeletons from a contemporary Brazilian collection. Brazilian Journal of Development 2021, 7(5): 44706-44721. (DOI:10.34117/bjdv7n5-069)

APA	erdoğan m, SEYHAN S (2023). A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. , 193 - 203. 10.29400/tjgeri.2023.345
Chicago	erdoğan mehmet mustafa,SEYHAN SINAN A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. (2023): 193 - 203. 10.29400/tjgeri.2023.345
MLA	erdoğan mehmet mustafa,SEYHAN SINAN A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. , 2023, ss.193 - 203. 10.29400/tjgeri.2023.345
AMA	erdoğan m,SEYHAN S A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. . 2023; 193 - 203. 10.29400/tjgeri.2023.345
Vancouver	erdoğan m,SEYHAN S A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. . 2023; 193 - 203. 10.29400/tjgeri.2023.345
IEEE	erdoğan m,SEYHAN S "A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS." , ss.193 - 203, 2023. 10.29400/tjgeri.2023.345
ISNAD	erdoğan, mehmet mustafa - SEYHAN, SINAN. "A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS". (2023), 193-203. https://doi.org/10.29400/tjgeri.2023.345

APA	erdoğan m, SEYHAN S (2023). A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. Türk Geriatri Dergisi, 26(2), 193 - 203. 10.29400/tjgeri.2023.345
Chicago	erdoğan mehmet mustafa,SEYHAN SINAN A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. Türk Geriatri Dergisi 26, no.2 (2023): 193 - 203. 10.29400/tjgeri.2023.345
MLA	erdoğan mehmet mustafa,SEYHAN SINAN A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. Türk Geriatri Dergisi, vol.26, no.2, 2023, ss.193 - 203. 10.29400/tjgeri.2023.345
AMA	erdoğan m,SEYHAN S A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. Türk Geriatri Dergisi. 2023; 26(2): 193 - 203. 10.29400/tjgeri.2023.345
Vancouver	erdoğan m,SEYHAN S A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS. Türk Geriatri Dergisi. 2023; 26(2): 193 - 203. 10.29400/tjgeri.2023.345
IEEE	erdoğan m,SEYHAN S "A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS." Türk Geriatri Dergisi, 26, ss.193 - 203, 2023. 10.29400/tjgeri.2023.345
ISNAD	erdoğan, mehmet mustafa - SEYHAN, SINAN. "A SINGLE-CENTER, CROSS-SECTIONAL PREVALENCE STUDY OF CERVICAL DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS". Türk Geriatri Dergisi 26/2 (2023), 193-203. https://doi.org/10.29400/tjgeri.2023.345