TY  - JOUR
TI  - Hazelnut-enriched diet effectively increases lipoproteins' resistance to oxidation in hypercholesterolemic subjects
AB  - Oxidative modifications of lipoproteins are crucial in the early stages of cardiovascular diseases (CVD) like hypercholesterolemia. The major aim is to determine the effects of hazelnut consump- tion on the resistance of low- and high-density lipoproteins to oxidation in hypercholesterolemic subjects. Fifteen hypercholesterolemic subjects (13 men, 2 women) who did not require drug tre- atment according to the National Cholesterol Education Program Adult Treatment Panel III criteria and had serum levels of TC˃200 mg/dL were included in the study. This study was designed as a dual control sandwich model intervention with a single group, isoenergetic three periods. The pe- riods were; Control Diet I (30 days), Hazelnut-Enriched Diet (30 days), and Control Diet II (30 days). The susceptibility of LDL and HDL to copper-mediated oxidation was determined spect- rophotometrically by following conjugated diene formation. The resistance of lipoproteins, mainly LDL, was increased by hazelnut consumption. It can be concluded that a hazelnut-enriched diet had protective effects against lipoprotein oxidation in hypercholesterolemic subjects. These chan- ges may play important roles in reducing the development of the atherosclerotic process.
AU  - AKCAN, Buket
AU  - Orem, Asım
AU  - VANİZOR KURAL, Birgül
AU  - örem, Cihan
AU  - BALABAN YUCESAN, Fulya
AU  - altinkaynak, yahya
DO  - 10.3153/FH23019
PY  - 2023
JO  - Food and Health
VL  - 9
IS  - 3
SN  - 2602-2834
SP  - 201
EP  - 211
DB  - TRDizin
UR  - http://search/yayin/detay/1189032
ER  -