COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS

Birinci, Mehmet; BEYAZAL ÇELİKER, FATMA; yemiş, tuğba; kupik, osman; terzi, suat; Bedir, Recep; Ozergin Coskun, Zerrin; Demir, Emine; DURSUN, Engin; Çelebi Erdivanlı, Özlem; Çeliker, Metin

COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS

Mehmet BİRİNCİ, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, Rize, Türkiye)

Fatma BEYAZAL ÇELİKER, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Radyoloji, Rize, Türkiye)

Tuğba YEMİŞ, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, Rize, Türkiye)

Osman KUPIK, (Muğla Sıtkı Koçman Üniversitesi, Tıp Fakültesi, Nükleer Tıp, Muğla, Türkiye)

Suat TERZİ, (İmparatorluk Hastanesi, Kulak Burun Boğaz, Trabzon, Türkiye)

Recep BEDİR, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Patoloji, Rize, Türkiye)

Zerrin ÖZERGİN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, Rize, Türkiye)

Emine DEMİR, (Altunbaş Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, İstanbul, Türkiye)

Engin DURSUN, (Lokman Hekim Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, Ankara, Türkiye)

Özlem ÇELEBİ ERDİVANLI, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, Rize, Türkiye)

Metin ÇELKER, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz, Rize, Türkiye)

Diğer Yazarlar

KBB-Forum

7 2

Yıl: 2023 Cilt: 22 Sayı: 2 Sayfa Aralığı: 130 - 135 Metin Dili: İngilizce İndeks Tarihi: 25-07-2023

COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS

Öz:

Objective: Laryngeal cancer is the most common malignancy of the head and neck region, following skin tumors. Cartilage invasion is an important feature in staging of laryngeal cancers. This study compared three frequently used radiologic tests used to detect cartilage invasion in laryngeal cancers. Materials and Methods: Medical records of 33 patients, who underwent total laryngectomy between 2014 and 2018, were retrospectively reviewed. Data from 11 patients, who had undergone both PET/CT, CT, and MRI were analyzed. The radiologic test results were re-evaluated for cartilage invasion by one radiologist and one nuclear medicine specialist experienced in head and neck cancers, who were blinded to any other patient data. The scores given by the examiners were compared with the pathology specimen results to form a confusion matrix. Results: All except 1 patient were male (91%). The mean age was 64 years (51-80). All except 1 patient had a history of smoking. TNM staging was T4a in 6 patients, T2 in 4 patients, and T3 in 1 patient. Two patients received salvage surgery after radiotherapy. Most frequent tumor localization was transglottic. PET/CT, CT, and MRI methods were all 83.3% sensitive, specificity was 80%, 60%, 40%; positive predictive value was 83.3%, 75%, 62.5%; negative predictive value was 72.7%, 66%, 80%, and the accuracy was 81.8%, 72.7%, 63.6%, respectively. Conclusions: Despite similar sensitivity, PET/CT examination scored best in specificity, positive and negative predictive value, whereas MRI scored worst.

Anahtar Kelime:

BİLGİSAYARLI TOMOGRAFİ, MAGNETİK REZONANS GÖRÜNTÜLEME VE POZİTRON EMİSYON TOMOGRAFİSİNİN LARİNKS KANSERLERİNDE KIKIRDAK İNVAZYONUNU SAPTAMADA KARŞILAŞTIRILMASI

Öz:

Amaç: Larinks kanseri cilt tümörlerinden sonra baş boyun bölgesinin en sık görülen maligniteleridir. Kıkırdak invazyonu larinks kanserlerinin evrelemesinde önemli bir özelliktir. Bu çalışmada larinks kanserlerinde sıkça kullanılan görüntüleme yöntemlerinden PET/BT, BT, ve MRG"nin kıkırdak invazyonunu saptamadaki rolü incelenmiştir. Gereç ve Yöntem: 2014-2018 tarihleri arasında total larenjektomi operasyonu uygulanmış 33 hastanın dosyası retrospektif olarak incelenmiştir. Çalışmaya PET/BT, BT, ve MRG tetkiklerinin tamamının olduğu 11 hastanın verileri analiz edildi. Çalışmaya dahil edilen hastaların operasyon öncesi yapılan görüntüleme yöntemleri baş boyun kanserleri konusunda tecrübeli, hasta verilerinin gizlendiği, bir radyolog ve bir nükleer tıp uzmanı tarafından kıkırdak invazyonu açısından tekrar değerlendirildi. Değerlendirme sonuçları histopatolojik inceleme sonuçlarıyla karşılaştırılarak hata matrisi oluşturuldu. Bulgular: Bir hariç tüm hastalar erkekti (%91). Ortalama yaş 64 (51-80) yıldı. Biri hariç tüm hastaların sigara kullanım öyküsü mevcuttu. TNM evresi 6 hastada T4a, 4 hastada T2, 1 hastada T3 idi. İki hasta radyoterapi sonrası nüks nedeniyle kurtarma cerrahisi uygulanmıştı. En sık tümör lokalizasyonu transglottik bölgeydi. PET/BT, BT, MRG yöntemleri için sensitivite %83.3; spesifite %80, %60, %40; pozitif prediktif değer %83.3, %75, %62.5; negatif prediktif değer %80, %72.7, %66 ve doğruluk %81.8, %72,7, %63.6 olarak saptandı. Sonuçlar: Spesifisite, pozitif ve negatif prediktif değer açısından PET/CT en iyi, MRG ise en kötü skora sahip oldu.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Birinci M, BEYAZAL ÇELİKER F, yemiş t, kupik o, terzi s, Bedir R, Ozergin Coskun Z, Demir E, DURSUN E, Çelebi Erdivanlı Ö, Çeliker M (2023). COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. , 130 - 135.
Chicago	Birinci Mehmet,BEYAZAL ÇELİKER FATMA,yemiş tuğba,kupik osman,terzi suat,Bedir Recep,Ozergin Coskun Zerrin,Demir Emine,DURSUN Engin,Çelebi Erdivanlı Özlem,Çeliker Metin COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. (2023): 130 - 135.
MLA	Birinci Mehmet,BEYAZAL ÇELİKER FATMA,yemiş tuğba,kupik osman,terzi suat,Bedir Recep,Ozergin Coskun Zerrin,Demir Emine,DURSUN Engin,Çelebi Erdivanlı Özlem,Çeliker Metin COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. , 2023, ss.130 - 135.
AMA	Birinci M,BEYAZAL ÇELİKER F,yemiş t,kupik o,terzi s,Bedir R,Ozergin Coskun Z,Demir E,DURSUN E,Çelebi Erdivanlı Ö,Çeliker M COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. . 2023; 130 - 135.
Vancouver	Birinci M,BEYAZAL ÇELİKER F,yemiş t,kupik o,terzi s,Bedir R,Ozergin Coskun Z,Demir E,DURSUN E,Çelebi Erdivanlı Ö,Çeliker M COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. . 2023; 130 - 135.
IEEE	Birinci M,BEYAZAL ÇELİKER F,yemiş t,kupik o,terzi s,Bedir R,Ozergin Coskun Z,Demir E,DURSUN E,Çelebi Erdivanlı Ö,Çeliker M "COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS." , ss.130 - 135, 2023.
ISNAD	Birinci, Mehmet vd. "COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS". (2023), 130-135.

APA	Birinci M, BEYAZAL ÇELİKER F, yemiş t, kupik o, terzi s, Bedir R, Ozergin Coskun Z, Demir E, DURSUN E, Çelebi Erdivanlı Ö, Çeliker M (2023). COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. KBB-Forum, 22(2), 130 - 135.
Chicago	Birinci Mehmet,BEYAZAL ÇELİKER FATMA,yemiş tuğba,kupik osman,terzi suat,Bedir Recep,Ozergin Coskun Zerrin,Demir Emine,DURSUN Engin,Çelebi Erdivanlı Özlem,Çeliker Metin COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. KBB-Forum 22, no.2 (2023): 130 - 135.
MLA	Birinci Mehmet,BEYAZAL ÇELİKER FATMA,yemiş tuğba,kupik osman,terzi suat,Bedir Recep,Ozergin Coskun Zerrin,Demir Emine,DURSUN Engin,Çelebi Erdivanlı Özlem,Çeliker Metin COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. KBB-Forum, vol.22, no.2, 2023, ss.130 - 135.
AMA	Birinci M,BEYAZAL ÇELİKER F,yemiş t,kupik o,terzi s,Bedir R,Ozergin Coskun Z,Demir E,DURSUN E,Çelebi Erdivanlı Ö,Çeliker M COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. KBB-Forum. 2023; 22(2): 130 - 135.
Vancouver	Birinci M,BEYAZAL ÇELİKER F,yemiş t,kupik o,terzi s,Bedir R,Ozergin Coskun Z,Demir E,DURSUN E,Çelebi Erdivanlı Ö,Çeliker M COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS. KBB-Forum. 2023; 22(2): 130 - 135.
IEEE	Birinci M,BEYAZAL ÇELİKER F,yemiş t,kupik o,terzi s,Bedir R,Ozergin Coskun Z,Demir E,DURSUN E,Çelebi Erdivanlı Ö,Çeliker M "COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS." KBB-Forum, 22, ss.130 - 135, 2023.
ISNAD	Birinci, Mehmet vd. "COMPARISON OF COMPUTED TOMOGRAPHY, MAGNETİC RESONANCE IMAGING AND POSITRON EMISSION TOMOGRAPHY IN DETECTING CARTILAGE INVASION IN LARYNX CANCERS". KBB-Forum 22/2 (2023), 130-135.