Yıl: 2023 Cilt: 11 Sayı: 6 Sayfa Aralığı: 1056 - 1059 Metin Dili: İngilizce DOI: 10.24925/turjaf.v11i6.1056-1059.5995 İndeks Tarihi: 27-07-2023

Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province

Öz:
Medicinal plants are quite popular in the medicine development process because they contain bioactive chemicals. Traditional medicine has made extensive use of Crataegus orientalis L., which also has significant biological effects. In this study, essential oils (EOs) of C. orientalis var. orientalis collected from Tokat-Türkiye were isolated by hydrodistillation. Chemical constituents were detected by GC-MS and benzaldehyde (%52.75), α-terpineol (%16.86), germacrene D (%7.03) and caryophyllene (%6.77) were determined as major components. Moreover, antioxidant analyses including DPPH•, ABTS+• and FRAP tests were carried out. EOs displayed good the DPPH activity (IC50, 12.21, µg/mL) in comparison to the standard BHT (IC50, 10.23 µg/mL). The same trend was observed for ABTS and FRAP assays.
Anahtar Kelime:

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  • Abed MN, Alassaf FA, Jasim MH, Alfahad M, Qazzaz ME. 2020. Comparison of antioxidant effects of the proton pump inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole. Pharmacology. 105: 645-651. doi: 10.1159/000506232
  • Agiel N, Hanoglu DY, Hanoglu A, Baser KH, Mericli F. 2019. Volatile oil constituents of Crataegus azarolus L. and Crataegus pallasii Grisb. Rec Nat Prod. 13: 405-412. doi.org/10.25135/rnp.123.18.11.1060
  • Baghi R, Helmig D, Guenther A, Duhl T, Daly R. 2012. Contribution of flowering trees to urban atmospheric biogenic volatile organic compound emissions. Biogeosciences. 9: 3777-3785. doi.org/10.5194/bg-9-3777-2012, 2012
  • Bakkali F, Averbeck S, Averbeck D, Idaomar M. 2008. Biological effects of essential oils–a review. Food and chemical toxicology. 46: 446-475. doi.org/10.1016/ j.fct.2007.09.106
  • Bicas JL, Neri-Numa IA., Ruiz ALT, De Carvalho JE, Pastore GM. 2011. Evaluation of the antioxidant and antiproliferative potential of bioflavors. Food Chem Toxicol. 49: 1610-1615. doi.org/10.1016/j.fct.2011.04.012
  • Bor Z, Arslan R, Bektas N, Pirildar S, and Dönmez AA. 2012. Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves. Turk J Med Sci. 42: 315-324. doi.org/10.3906/sag-1011-1304
  • Boudjada AT, Bendif H, Bensouici C, Rhouati S. 2018. Phytochemical constituents, phenolic contents, and antioxidant activity of Crataegus azarolus extracts. Asian J Pharm Clin Res. 11: 133-137. doi.org/10.22159/ ajpcr.2018.v11i4.23724
  • Erenler R, Demirtas I, Karan T, Gul F, Kayir O, Karakoc OC. 2018. Chemical constituents, quantitative analysis and insecticidal activities of plant extract and essential oil from Origanum onites L. Trends Phytochem Res. 2: 91-96. doi.org/10.53445/batd.1210373
  • Froehlicher T, Hennebelle T, Martin-Nizard F, Cleenewerck P, Hilbert JL, Trotin F, Grec S. 2009. Phenolic profiles and antioxidative effects of hawthorn cell suspensions, fresh fruits, and medicinal dried parts. Food Chem. 115: 897-903.
  • Horoz M, Gok E, Genctoy G, Ozcan T, Olmaz R, Akca M et al. 2008. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Inter Med. 47: 2039-42. doi: 10.2169/internalmedicine.47.15
  • Karan T, Simsek S, Yildiz I, Erenler R. 2018. Chemical composition and insecticidal activity of Origanum syriacum L. essential oil against Sitophilus oryzae and Rhyzopertha dominica. Int J Second Metab. 5: 87-93. doi.org/10.21448/ ijsm.404114
  • Khaleel C, Tabanca N, Buchbauer G. 2018. α-Terpineol, a natural monoterpene: A review of its biological properties. Open Chem. 16: 349-361. doi.org/10.1515/chem-2018-0040
  • Kovaleva AM, Goncharov NF, Komissarenko AN, Sidora NV, Kovalev SV. 2009. GC/MS study of essential oil components from flowers of Crataegus jackii, C. robesoniana, and C. flabellata. Chem. Nat. Compd. 4: 582–584.
  • Lakache Z, Tigrine-Kordjani N, Tigrine C, Kameli A, Meklati BY. 2014. Volatile constituents, phenolic compounds, and antioxidant activity of Crataegus azarolus leaves and flowers growing in Algeria. Chem Nat Compd. 50: 1132-1135. doi.org/10.1007/s10600-014-1183-6
  • Ljubuncic P, Azaizeh H, Cogan U, Bomzon A. 2006. The Effects of a Decoction Prepared from the Leaves and Unripe Fruits of Crataegus aronia in Streptozotocin Induced Diabetic Rats. J Complement Integr Med. 3: 1-11. doi.org/10.1016/ j.jep.2005.04.024
  • Nabavi SF, Habtemariam S, Ahmed T, Sureda A, Daglia M, Sobarzo E, and Nabavi SM. 2015. Polyphenolic composition of Crataegus monogyna Jacq. From chemistry to medical applications. Nutrients. 7: 7708-7728. doi.org/10.3390%2Fnu7095361
  • Ozderin S, Fakir H, Dönmez İE. 2015. Determination to volatile components of some Crataegus orientalis Pall Ex M Bieb taxa in Muğla-Fethiye Province. J Appl Nat Sci. 19: 120-123.
  • Ozderin S, Fakir H, Dönmez E. 2016. Chemical properties of hawthorn (Crataegus spp.) taxa naturally distributed in western Anatolia part of Türkiye. Prethodnopriopćenje. 7: 369–376. doi.org/10.31298/SL.140.7-8.5
  • Pellegrini N, Miglio C, Del Rio D. 2009. Effect of domestic cooking methods on the total antioxidant capacity of vegetables. Int J Food Sci Nutr. 60: 12-22. doi.org/10.1080/09637480802175212
  • Poprac P, Jomova K, Simunkova M, Kollar V, Rhodes CJ, Valko M. 2017. Targeting free radicals in oxidative stress-related human diseases. Trends Pharmacol Sci. 38: 592-607.
  • Rigelsky JM, Sweet BV. 2002. Hawthorn: pharmacology and therapeutic uses. Am J Health Syst Pharma. 59: 417-422. doi: 10.1016/j.tips.2017.04.005
  • Samet H, Cikili Y. (2015). Importance of medicinal and aromatic plants as an alternative crop in the rural development of Türkiye. J Rural Dev. 10: 75-84.
  • Savikin KP, Krstić-Milošević DB, Menković NR, Beara IN, Mrkonjić ZO, Pljevljakušić DS. 2017. Crataegus orientalis leaves and berries: Phenolic profiles, antioxidant and anti inflammatory activity. Nat Prod Commun.12: 159-162. doi.org/10.1177/1934578X1701200204
  • Sharma N, Tripathi A. 2008. Effects of Citrus sinensis (L.) Osbeck epicarp essential oil on growth and morphogenesis of Aspergillus niger (L.) Van Tieghem. Microbiol Res. 163: 337-344. doi.org/10.1016/j.micres.2006.06.009
  • Skerget M, Kotnik P, Hadolin M, Hras AR, Simonic M, Knez Z. 2005. Phenols, proanthocyanidins. Flavones and flavonols in some plant materials and their antioxidant activities. Food Chem. 89: 191-198.
  • Tabaszewska M, Najgebauer-Lejko D, Zbylut-Górska M. 2022. The Effect of Crataegus Fruit Pre-Treatment and Preservation Methods on the Extractability of Aroma Compounds during Liqueur Production. Molecules, 27: 1516- 1533. doi.org/10.3390/molecules27051516
  • Turek C, Stintzing FC. 2013. Stability of essential oils: a review. Comprehensive reviews in food science and food safety, 12: 40-53. doi.org/10.1111/1541-4337.12006
  • Ullah I, Khan AL, Alı L, Khan AR, Waqas M, Hussain J, Shin JH. (2015). Benzaldehyde as an insecticidal, antimicrobial, and antioxidant compound produced by Photorhabdus temperata M1021. J Microbiol. 53: 127-133. doi: 10.1007/s12275-015-4632-4.
  • Vasisht K, Sharma N, Karan M. 2016. Current perspective in the international trade of medicinal plants material: an update. Curr Pharm Des. 22: 4288-4336. doi.org/10.2174/ 1381612822666160607070736
  • Verma SK, Jain V, Verma D, and Khamesra R. 2007. Crataegus oxyacantha-A Cardioprotective Herb. J Herb Med Toxicol. 1: 65-71.
  • Wang T, Zhang P, Zhao C, Zhang Y, Liu H, Hu L, Gao X, Zhang D. 2011. Prevention effect in selenite-induced cataract in vivo and antioxidative effects in vitro of Crataegus pinnatifida leaves. Biol. Trace Elem. Res. 1: 106–116. doi.org/10.1007/s12011-010-8752-8
  • Zhang Z, Chang Q, Zhu M, Huang Y, Ho WK, Chen ZY. 2001. Characterization of antioxidants present in hawthorn fruits. J Nutr Biochem. 12: 144-152.
APA Karan T, ÇAKIR S (2023). Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. , 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
Chicago Karan Tünay,ÇAKIR Sema Gül Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. (2023): 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
MLA Karan Tünay,ÇAKIR Sema Gül Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. , 2023, ss.1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
AMA Karan T,ÇAKIR S Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. . 2023; 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
Vancouver Karan T,ÇAKIR S Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. . 2023; 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
IEEE Karan T,ÇAKIR S "Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province." , ss.1056 - 1059, 2023. 10.24925/turjaf.v11i6.1056-1059.5995
ISNAD Karan, Tünay - ÇAKIR, Sema Gül. "Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province". (2023), 1056-1059. https://doi.org/10.24925/turjaf.v11i6.1056-1059.5995
APA Karan T, ÇAKIR S (2023). Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. Türk Tarım - Gıda Bilim ve Teknoloji dergisi, 11(6), 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
Chicago Karan Tünay,ÇAKIR Sema Gül Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. Türk Tarım - Gıda Bilim ve Teknoloji dergisi 11, no.6 (2023): 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
MLA Karan Tünay,ÇAKIR Sema Gül Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. Türk Tarım - Gıda Bilim ve Teknoloji dergisi, vol.11, no.6, 2023, ss.1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
AMA Karan T,ÇAKIR S Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. Türk Tarım - Gıda Bilim ve Teknoloji dergisi. 2023; 11(6): 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
Vancouver Karan T,ÇAKIR S Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province. Türk Tarım - Gıda Bilim ve Teknoloji dergisi. 2023; 11(6): 1056 - 1059. 10.24925/turjaf.v11i6.1056-1059.5995
IEEE Karan T,ÇAKIR S "Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province." Türk Tarım - Gıda Bilim ve Teknoloji dergisi, 11, ss.1056 - 1059, 2023. 10.24925/turjaf.v11i6.1056-1059.5995
ISNAD Karan, Tünay - ÇAKIR, Sema Gül. "Determination of Antioxidant Activities of Essential Oils of Crataegus orientalis var. orientalis in Tokat (Türkiye) Province". Türk Tarım - Gıda Bilim ve Teknoloji dergisi 11/6 (2023), 1056-1059. https://doi.org/10.24925/turjaf.v11i6.1056-1059.5995