TY  - JOUR
TI  - Experimental intravaginal and intrauterine endometritis model: which model is more useful?
AB  - This study aims to compare the newly created intravaginal endometritis model (IVM) with the intrauterine endometritis model (IUM). E. coli infusion was used as intravaginally for IVM and intrauterinally for IUM model. The animals were exeuted on the 7th day. Histopathological and biochemical analyses [malondialdehyde (MDA), glutathione (GSH), Endocan, Endoglin] were performed. A significant inflammation was determined in IVM and IUM compared to the control. A significant decrease in GSH and a significant increase in MDA and Endoglin were determined in IVM and IUM compared to the control. There was a statistically significant increase in the IUM and a numerical increase in the IVM compared to the control. Endometritis was determined by histopathological and biochemical analyses in both IUM and IVM model. It is suggested that intravaginal administration, which is easier to perform, can be used in experimental endometritis model studies.
AU  - Beşeren, Hatice
AU  - MAKAV, MUSTAFA
AU  - KURU, Mushap
AU  - Adali, Yasemen
AU  - Coşkun, Mustafa Reha
AU  - EROĞLU, Huseyin Avni
DO  - 10.31797/vetbio.1147776
PY  - 2022
JO  - Journal of advances in vetbio science and techniques
VL  - 7
IS  - 3
SN  - 2548-1150
SP  - 366
EP  - 375
DB  - TRDizin
UR  - http://search/yayin/detay/1194658
ER  -