The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats

Abdullah ÖZBİLGİN, (Sivas Cumhuriyet Üniversitesi, Veteriner Fakültesi, Hayvan Besleme ve Beslenme Bozuklukları Anabilim Dalı, Sivas, Türkiye)
Recep GÜMÜŞ, (Sivas Cumhuriyet Üniversitesi, Veteriner Fakültesi, Hayvan Besleme ve Beslenme Bozuklukları Anabilim Dalı, Sivas, Türkiye)
Mehmet EKİCİ, (Sivas Cumhuriyet Üniversitesi, Veteriner Fakültesi, Fizyoloji Bölümü, Sivas, Türkiye)
Nazlı ERCAN (Sivas Cumhuriyet Üniversitesi, Veteriner Fakültesi, Biyokimya Bölümü, Sivas, Türkiye)
Journal of advances in vetbio science and techniques
4 2
Yıl: 2023 Cilt: 8 Sayı: 2 Sayfa Aralığı: 112 - 120 Metin Dili: İngilizce DOI: 10.31797/vetbio.1293543 İndeks Tarihi: 05-09-2023

The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats

Öz:
The aim of this study is to determine the effects of resveratrol used in adding it to drinking water. The study was carried out with 24 Wistar albino male 20 days rats for 40 days. The study design was determined as one control and two trial groups (each group with 2 parallels and each parallel with 4 rats). The first group was given a basal ration and drinking water. The second group was given the basal ration and drinking water with 10 mg/kg resveratrol; and the third group was given the basal ration and drinking water 20 mg/kg resveratrol. In serum biochemistry parameters, significant decreases were observed in serum Aspartate aminotransferase (AST) enzyme activity, blood urea nitrogen (BUN), albumin, total protein and globulin concentrations and increase in albumin/globulin ratio in groups given resveratrol (p<0.05). Regardless of the dose, an increase in the concentration of glutathione (GSH) from the antioxidant parameters was observed in the liver; In the kidney, an increase was observed in the Res10 group. In addition, a decrease in muscle superoxide dismutase (SOD) activity and an increase in muscle and kidney catalase (CAT) activity were observed. A decrease was observed in malondialdehyde (MDA) concentrations, which is a parameter of lipid peroxidation in the kidney. As a result, it was determined in the present study that resveratrol has antioxidant effects regardless of the way of use, and it was concluded that this additive can be used for various purposes.
Anahtar Kelime: Antioxidant serum biochemistry resveratrol rat water

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA özbilgin a, GÜMÜŞ R, EKICI M, Ercan N (2023). The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. , 112 - 120. 10.31797/vetbio.1293543
Chicago özbilgin abdullah,GÜMÜŞ Recep,EKICI MEHMET,Ercan Nazli The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. (2023): 112 - 120. 10.31797/vetbio.1293543
MLA özbilgin abdullah,GÜMÜŞ Recep,EKICI MEHMET,Ercan Nazli The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. , 2023, ss.112 - 120. 10.31797/vetbio.1293543
AMA özbilgin a,GÜMÜŞ R,EKICI M,Ercan N The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. . 2023; 112 - 120. 10.31797/vetbio.1293543
Vancouver özbilgin a,GÜMÜŞ R,EKICI M,Ercan N The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. . 2023; 112 - 120. 10.31797/vetbio.1293543
IEEE özbilgin a,GÜMÜŞ R,EKICI M,Ercan N "The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats." , ss.112 - 120, 2023. 10.31797/vetbio.1293543
ISNAD özbilgin, abdullah vd. "The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats". (2023), 112-120. https://doi.org/10.31797/vetbio.1293543
APA özbilgin a, GÜMÜŞ R, EKICI M, Ercan N (2023). The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. Journal of advances in vetbio science and techniques, 8(2), 112 - 120. 10.31797/vetbio.1293543
Chicago özbilgin abdullah,GÜMÜŞ Recep,EKICI MEHMET,Ercan Nazli The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. Journal of advances in vetbio science and techniques 8, no.2 (2023): 112 - 120. 10.31797/vetbio.1293543
MLA özbilgin abdullah,GÜMÜŞ Recep,EKICI MEHMET,Ercan Nazli The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. Journal of advances in vetbio science and techniques, vol.8, no.2, 2023, ss.112 - 120. 10.31797/vetbio.1293543
AMA özbilgin a,GÜMÜŞ R,EKICI M,Ercan N The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. Journal of advances in vetbio science and techniques. 2023; 8(2): 112 - 120. 10.31797/vetbio.1293543
Vancouver özbilgin a,GÜMÜŞ R,EKICI M,Ercan N The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats. Journal of advances in vetbio science and techniques. 2023; 8(2): 112 - 120. 10.31797/vetbio.1293543
IEEE özbilgin a,GÜMÜŞ R,EKICI M,Ercan N "The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats." Journal of advances in vetbio science and techniques, 8, ss.112 - 120, 2023. 10.31797/vetbio.1293543
ISNAD özbilgin, abdullah vd. "The effect of resveratrol on live weight, serum biochemistry and tissue antioxidant enzymes in rats". Journal of advances in vetbio science and techniques 8/2 (2023), 112-120. https://doi.org/10.31797/vetbio.1293543
Sayfa Oluşturulma Tarihi
24-04-2024 9:1

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