Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study
Yıl: 2023 Cilt: 45 Sayı: 2 Sayfa Aralığı: 290 - 300 Metin Dili: İngilizce DOI: 10.20515/otd.1230770 İndeks Tarihi: 06-09-2023
Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study
Öz: This study investigates the associations of ABO blood groups on long-term COVID patients who applied to the COVID-19 Fol- low-up Center. New co-morbidities after COVID-19 were also evaluated. Methods: This study was designed retrospectively with patients admitted to COVID-19 Follow-up Center between December 13, 2020, and November 1, 2021. The study sample consis- ted of 502 patients divided into four groups according to their blood types. Patients were analyzed according to their symptoms and our findings after COVID-19 by blood group variable. Newly diagnosed co-morbidities were recorded from patient’s files, and the drug history of the patients was investigated A total of 502 COVID-19 patients were retrospectively analyzed, and the mean age was 55.5(±13.2) years. Patients were predominantly female (263/502) (52.4%). While long-term COVID-19 symptoms were observed in 76.9% of the patients, extreme fatigue (46.2%) and ongoing shortness of breath (32.9%) were observed most frequently. No relationship was found between other prolonged symptoms of the disease and blood groups except heart palpitation with blood groups A and B compared to AB and O (p=0.048) . In addition, there was no significant difference in the ongoing symptoms and inflammatory parameters like C-Reactive Protein and Lymphocyte count. This study demonstrated no difference between blood types and long-term COVID-19 patients' clinical features.
Anahtar Kelime: Uzun Dönem COVID-19 Hastalarında ABO Kan Grubu Dağılımı ile Klinik Özellikler Arasındaki İlişkinin Değerlendirilmesi: Retrospektif Bir Çalışma
Öz: Bu çalışma, COVID-19 İzlem Merkezine başvuran uzun süreli COVID hastalarında kan grupları arasındaki ilişkilerin araştırılma- sını amaçlamaktadır. COVID-19 sonrası yeni komorbiditeler de değerlendirilmiştir. Bu çalışma, 13 Aralık 2020 ile 01 Kasım 2021 tarihleri arasında COVID-19 İzlem Merkezi'ne başvuran hastalar ile retrospektif olarak tasarlandı. Çalışmanın örneklemini, kan gruplarına göre 4 gruba ayrılan 502 hasta oluşturdu. Hastalar kan grubu değişkenine göre COVID-19 sonrası semptomlarına ve bulgularına göre analiz edildi. Hasta dosyalarından yeni tanı konulan ek hastalıklar kaydedildi ve hastaların ilaç öyküsü araştırıldı. Toplam 502 COVID-19 hastası retrospektif olarak incelendi ve yaş ortalaması 55,5(±13,2) idi. Hastaların çoğunluğunu kadınlar oluşturmaktaydı (263/502) [%52.4]. Hastaların %76,9'unda uzun süreli COVID-19 semptomları görülürken, en sık aşırı yorgun- luk (%46,2) ve devam eden nefes darlığı (%32,9) görüldü. Uzun süreli COVID semptomları değerlendirildiğinde, AB ve O'ya kıyasla A ve B kan grupları ile ilişkili tek semptom kalp çarpıntısıydı (p=0,048). Hastaların kan grupları ile hastalığın semptomları ve seyri arasında anlamlı bir ilişki bulunmadı. Ayrıca devam eden semptomlarda ve C-Reaktif Protein ve lenfosit sayımı gibi inflamatuar parametrelerde anlamlı fark yoktu. Bu çalışma, kan grupları ile uzun süreli COVID-19 hastalarının klinik özellikleri arasında fark olmadığını göstermiştir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Nejadghaderi SA, Saghazadeh A, Rezaei N. Health Care Policies and COVID-19 Prevalence: Is There Any Association? 2022 Jan 1 [cited 2022 Aug 11];52(1):9–22. Available from: https://pubmed.ncbi.nlm.nih.gov/33686893/
- 2. WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data [Internet]. [cited 2021 April 22]. Available from: https://covid19.who.int/
- 3. Berger SA, Young NA, Edberg SC. Relationship between infectious diseases and human blood type. 1989 Aug [cited 2022 Feb 22];8(8):681–9. Available from: https://link.springer.com/article/10.1007/BF01963752
- 4. Liu Y, Häussinger L, Steinacker JM, Dinse-Lambracht A. Association between the dynamics of the COVID-19 epidemic and ABO blood type distribution. 2021 [cited 2022 February 22];149. Available from: https://pubmed.ncbi.nlm.nih.gov/33407977/
- 5. Cheng Y, Cheng G, Chui CH, Lau FY, Chan PKS, Ng MHL, et al. ABO blood group and susceptibility to severe acute respiratory syndrome. JAMA [Internet]. 2005 Mar 23 [cited 2021 Dec 13];293(12):1450–1. Available from: https://pubmed.ncbi.nlm.nih.gov/15784866/
- 6. Zhao J, Yang Y, Huang H, Li D, Gu D, Lu X, et al. Relationship Between the ABO Blood Group and the Coronavirus Disease 2019 (COVID-19) Susceptibility. Clin Infect Dis [Internet]. 2021 Jul 15 [cited 2021 Dec 13];73(2):328–31. Available from: https://pubmed.ncbi.nlm.nih.gov/32750119/
- 7. Zietz M, Zucker J, Tatonetti NP. Associations between blood type and COVID-19 infection, intubation, and death. Nat Commun [Internet]. 2020 December 1 [cited 2022 February 22];11(1). Available from: https://pubmed.ncbi.nlm.nih.gov/33188185/
- 8. Shokri P, Golmohammadi S, Noori M, Nejadghaderi SA, Carson-Chahhoud K, Safiri S. The relationship between blood groups and risk of infection with SARS-CoV-2 or development of severe outcomes: A review. Rev Med Virol [Internet]. 2022 January 1 [cited 2022 August 11];32(1):e2247. Available from: https://onlinelibrary.wiley.com/doi/full/10.1002/rmv.2247
- 9. Gérard C, Maggipinto G, Minon JM. COVID-19 and ABO blood group: another viewpoint. Br J Haematol [Internet]. 2020 Jul 1 [cited 2022 Aug 11];190(2):e93–4. Available from: https://pubmed.ncbi.nlm.nih.gov/32453863/
- 10. Liu N, Zhang T, Ma L, Zhang H, Wang H, Wei W, et al. The impact of ABO blood group on COVID-19 infection risk and mortality: A systematic review and meta-analysis. 2021 July 1 [cited 2022 August 11];48:100785. Available from: https://pubmed.ncbi.nlm.nih.gov/33309392/
- 11. Yelin D, Wirtheim E, Vetter P, Kalil AC, Bruchfeld J, Runold M, et al. Long-term consequences of COVID-19: research needs [Internet]. October 1, 2020. Available from: /pmc/articles/PMC7462626/
- 12. Balachandar V, Mahalaxmi I, Subramaniam M, Kaavya J, Senthil Kumar N, Laldinmawii G, et al. Follow-up studies in COVID-19 recovered patients - is it mandatory? [Internet]. August 10, 2020 p. 139021. Available from: https://pubmed.ncbi.nlm.nih.gov/32360909/
- 13. Davison GM, Hendrickse HL, Matsha TE. Do Blood Group Antigens and the Red Cell Membrane Influence Human Immunodeficiency Virus Infection? Cells [Internet]. 2020 March 31 [cited 2022 February 24];9(4). Available from: https://pubmed.ncbi.nlm.nih.gov/32244465/
- 14. Tyrrell DAJ, Sparrow P, Beare AS. Relation between Blood Groups and Resistance to Infection with Influenza and some Picornaviruses. Nat 1968 2205169 [Internet]. 1968 [cited 2022 Feb 24];220(5169):819–20. Available from: https://www.nature.com/articles/220819a0
- 15. Hashan MR, Ghozy S, El-Qushayri AE, Pial RH, Hossain MA, Al Kibria GM. Association of dengue disease severity and blood group: A systematic review and meta-analysis. 2021 January 1 [cited 2022 September 2];31(1):1–9. Available from: https://pubmed.ncbi.nlm.nih.gov/32776660/
- 16. Noori M, Shokri P, Nejadghaderi SA, Golmohammadi S, Carson-Chahhoud K, Bragazzi NL, et al. ABO blood groups and risk of human immunodeficiency virus infection: A systematic review and meta-analysis. 2022 May 1 [cited 2022 September 2];32(3):e2298. Available from: https://onlinelibrary.wiley.com/doi/full/10.1002/rmv.2298
- 17. Rios M, Bianco C. The role of blood group antigens in infectious diseases. 2000 Apr 1 [cited 2022 Feb 24];37(2):177–85. Available from: https://pubmed.ncbi.nlm.nih.gov/10791886/
- 18. Ray JG, Schull MJ, Vermeulen MJ, Park AL. Association Between ABO and Rh Blood Groups and SARS-CoV-2 Infection or Severe COVID-19 Illness : A Population-Based Cohort Study. Ann Intern Med [Internet]. 2021 Mar 1 [cited 2022 Feb 24];174(3):308–15. Available from: https://pubmed.ncbi.nlm.nih.gov/33226859/
- 19. Pourali F, Afshari M, Alizadeh-Navaei R, Javidnia J, Moosazadeh M, Hessami A. Relationship between blood group and risk of infection and death in COVID-19: a live meta-analysis. New microbes new Infect [Internet]. 2020 September 1 [cited 2022 September 2];37. Available from: https://pubmed.ncbi.nlm.nih.gov/32837730/
- 20. Mendy A, Keller JL, Apewokin S, Morrow AL. Is Blood Type Associated with COVID-19 Severity? medRxiv [Internet]. 2020 August 14 [cited 2022 February 24];2020.08.11.20172676. Available from: https://www.medrxiv.org/content/10.1101/2020.08.11.20172676v1
- 21. Rathmann W, Kuss O, Kostev K. Incidence of newly diagnosed diabetes after Covid-19. Diabetologia [Internet]. 2022 [cited 2022 May 9];65(6):949–54. Available from: https://pubmed.ncbi.nlm.nih.gov/35292829/
- 22. Noori M, Nejadghaderi SA, Sullman MJM, Carson-Chahhoud K, Ardalan M, Kolahi AA, et al. A Review on the Possible Pathophysiology of Potassium Abnormalities in COVID-19. Iran J Kidney Dis. 2021 November 1;15(6):397–407.
- 23. Dixit NM, Churchill A, Nsair A, Hsu JJ. Post-Acute COVID-19 Syndrome and the cardiovascular system: What is known? 2021 May 1 [cited 2022 May 9];5:100025. Available from: https://pubmed.ncbi.nlm.nih.gov/34192289/
- 24. Akpek M. Does COVID-19 Cause Hypertension? Angiology [Internet]. 2022 August 1 [cited 2023 January 27];73(7):682. Available from: /pmc/articles/PMC9260192/
- 25. Wu Y, Feng Z, Li P, Yu Q. Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19. 2020 October 1 [cited 2021 December 13];509. Available from: https://pubmed.ncbi.nlm.nih.gov/32562665/
- 26. Cirulli ET, Schiabor KM, 1 B, Riffle S, Bolze A, Neveux I, et al. Long-term COVID-19 symptoms in a large unselected population. medRxiv [Internet]. 2020 December 1 [cited 2023 January 27];2020.10.07.20208702. Available from: https://www.medrxiv.org/content/10.1101/2020.10.07.20208702v3
- 27. Gallo Marin B, Aghagoli G, Lavine K, Yang L, Siff EJ, Chiang SS, et al. Predictors of COVID-19 severity: A literature review. Rev Med Virol [Internet]. 2021 January 1 [cited 2022 September 2];31(1). Available from: /pmc/articles/PMC7855377/
- 28. Malik P, Patel U, Mehta D, Patel N, Kelkar R, Akrmah M, et al. Biomarkers and outcomes of COVID-19 hospitalizations: systematic review and meta-analysis. 2021 Jun 1 [cited 2022 Sep 2];26(3):107–8. Available from: https://ebm.bmj.com/content/26/3/107
- 29. Kiss S, Gede N, Hegyi PJ, Németh D, Földi M, Dembrovszky F, et al. Early changes in laboratory parameters are predictors of mortality and ICU admission in patients with COVID-19: a systematic review and meta-analysis. Med Microbiol Immunol [Internet]. 2021 Feb 1 [cited 2022 Sep 2];210(1):33. Available from: /pmc/articles/PMC7679241/
- 30. Minh LHN, Abozaid AAF, Ha NX, Le Quang L, Gad AG, Tiwari R, et al. Clinical and laboratory factors associated with coronavirus disease 2019 (Covid 19): A systematic review and meta analysis. Rev Med Virol [Internet]. 2021 November 1 [cited 2022 September 2];31(6). Available from: /pmc/articles/PMC8646520/
- 31. Sudre CH, Murray B, Varsavsky T, Graham MS, Penfold RS, Bowyer RC, et al. Attributes and predictors of long COVID. 2021 [cited 2022 Sep 2];27(4):626–31. Available from: https://pubmed.ncbi.nlm.nih.gov/33692530/
- 32. Latz CA, Decarlo C, Boitano L, Png CYMM, Patell R, Conrad MF, et al. Blood type and outcomes in patients with COVID-19. 2020 September 1 [cited 2021 December 13];99(9). Available from: /pmc/articles/PMC7354354/
- 33. Kozak R, Armstrong SM, Salvant E, Ritzker C, Feld J, Biondi MJ, et al. Recognition of long-covid-19 patients in a canadian tertiary hospital setting: A retrospective analysis of their clinical and laboratory characteristics. Pathogens [Internet]. 2021 October 1 [cited 2022 September 2];10(10). Available from: /pmc/articles/PMC8537802/
- 34. Fouladseresht H, Ghamar Talepoor A, Eskandari N, Norouzian M, Ghezelbash B, Beyranvand MR, et al. Potential Immune Indicators for Predicting the Prognosis of COVID-19 and Trauma: Similarities and Disparities. 2022 January 20 [cited 2022 September 2];12:5788. Available from: https://pubmed.ncbi.nlm.nih.gov/35126355/
- 35. Li J, Wang X, Chen J, Cai Y, Deng A, Yang M. Association between ABO blood groups and risk of SARS-CoV-2 pneumonia. Br J Haematol [Internet]. 2020 Jul 1 [cited 2022 Feb 25];190(1):24–7. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.16797
- 36. Barnkob MB, Pottegård A, Støvring H, Haunstrup TM, Homburg K, Larsen R, et al. Reduced prevalence of SARS-CoV-2 infection in ABO blood group O. 2020 Oct [cited 2022 February 25];4(20):4990–3. Available from: https://pubmed.ncbi.nlm.nih.gov/33057631/
| APA | Bildirici Y, UCAN A, Eker Güvenç Ş, Bilge u (2023). Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. , 290 - 300. 10.20515/otd.1230770 |
| Chicago | Bildirici Yaşar,UCAN ANIL,Eker Güvenç Şebnem,Bilge uğur Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. (2023): 290 - 300. 10.20515/otd.1230770 |
| MLA | Bildirici Yaşar,UCAN ANIL,Eker Güvenç Şebnem,Bilge uğur Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. , 2023, ss.290 - 300. 10.20515/otd.1230770 |
| AMA | Bildirici Y,UCAN A,Eker Güvenç Ş,Bilge u Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. . 2023; 290 - 300. 10.20515/otd.1230770 |
| Vancouver | Bildirici Y,UCAN A,Eker Güvenç Ş,Bilge u Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. . 2023; 290 - 300. 10.20515/otd.1230770 |
| IEEE | Bildirici Y,UCAN A,Eker Güvenç Ş,Bilge u "Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study." , ss.290 - 300, 2023. 10.20515/otd.1230770 |
| ISNAD | Bildirici, Yaşar vd. "Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study". (2023), 290-300. https://doi.org/10.20515/otd.1230770 |
| APA | Bildirici Y, UCAN A, Eker Güvenç Ş, Bilge u (2023). Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. Osmangazi Tıp Dergisi, 45(2), 290 - 300. 10.20515/otd.1230770 |
| Chicago | Bildirici Yaşar,UCAN ANIL,Eker Güvenç Şebnem,Bilge uğur Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. Osmangazi Tıp Dergisi 45, no.2 (2023): 290 - 300. 10.20515/otd.1230770 |
| MLA | Bildirici Yaşar,UCAN ANIL,Eker Güvenç Şebnem,Bilge uğur Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. Osmangazi Tıp Dergisi, vol.45, no.2, 2023, ss.290 - 300. 10.20515/otd.1230770 |
| AMA | Bildirici Y,UCAN A,Eker Güvenç Ş,Bilge u Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. Osmangazi Tıp Dergisi. 2023; 45(2): 290 - 300. 10.20515/otd.1230770 |
| Vancouver | Bildirici Y,UCAN A,Eker Güvenç Ş,Bilge u Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study. Osmangazi Tıp Dergisi. 2023; 45(2): 290 - 300. 10.20515/otd.1230770 |
| IEEE | Bildirici Y,UCAN A,Eker Güvenç Ş,Bilge u "Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study." Osmangazi Tıp Dergisi, 45, ss.290 - 300, 2023. 10.20515/otd.1230770 |
| ISNAD | Bildirici, Yaşar vd. "Evaluation of the Relationship Between ABO Blood Group Distribution and Clinical Features in Long-Term COVID-19 Patients: A retrospective study". Osmangazi Tıp Dergisi 45/2 (2023), 290-300. https://doi.org/10.20515/otd.1230770 |
