TY  - JOUR
TI  - Pharmacobiology of topical Ankaferd hemostat in neoplastic disorders
AB  - Ankaferd Hemostat (ABS) is a hemostatic agent of plant-extract acting on red blood cells used for achieving hemostasis. ABS has anti-inflammatory, anti-microbial, anti-fungal, anti-oxidative and anti-neoplastic effects. Cancer treatment is a challenging clinical condition that can lead to numerous clinical complications of different severity. Antineoplastic features of ABS had been depicted in many solid and hematological tumors. Supportive treatment of cancer is very important to decrease the mortality and morbidity of the cancer patients. ABS prevents and treats chemotherapy associated mucositis with its unique effects on the blood cells, endothelium, angiogenesis, cellular regeneration, wound healing and vascular dynamics. Those features of ABS bring it to be also beneficial for necrotizing enterocolitis as well. Besides its supportive and preventative roles in the cancer patients, ABS can also be potentially utilized as a chemoembolization agent within intratumoral treatment modality. The aim of this review is to summarize current pharmacobiology of topical ABS in neoplastic disorders.
AU  - Malkan, Umit Yavuz
AU  - Haznedaroglu, Ibrahim C.
DO  - 10.18621/eurj.1246824
PY  - 2023
JO  - The European Research Journal
VL  - 9
IS  - 5
SN  - 2149-3189
SP  - 1271
EP  - 1276
DB  - TRDizin
UR  - http://search/yayin/detay/1194906
ER  -