Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats

Volkan KOŞAL, (Van Yüzüncü Yıl Üniversitesi, Veteriner Fakültesi, Suni Tohumlama Anabilim Dalı, 65080, Van, Türkiye)
Ömer Faruk KELEŞ, (Van Yüzüncü Yıl Üniversitesi, Veteriner Fakültesi, Patoloji Anabilim Dalı, 65080, Van, Türkiye)
Ahmet Ufuk KÖMÜROĞLU, (Van Yüzüncü Yıl Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, 65080, Van, Türkiye)
Yıldıray BAŞBUĞAN (Van Yüzüncü Yıl Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, 65080, Van, Türkiye)
Van Veterinary Journal
0 2
Yıl: 2023 Cilt: 34 Sayı: 2 Sayfa Aralığı: 174 - 179 Metin Dili: İngilizce DOI: 10.36483/vanvetj.1301038 İndeks Tarihi: 14-09-2023

Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats

Öz:
Many health problems are seen due to aging. One of these is problems in the reproductive system. Reproductive system problems are caused by lower urinary system symptoms, prostate diseases, low fertility, testicular dysfunction. The aim of this study was to compare reproductive parameters of geriatric (3 years old) and young (3 months old) rats. A 3-year-old rat is equivalent to an average 90-95-year-old human. For this purpose, sperm analysis, testicular and prostate histopathology, testicular oxidative stress parameters were examined in geriatric (3 years old) and young (3 months old) rats. In the analysis results, it was determined that sperm motility ratio decreased (p<0.001), abnormal sperm ratio increased (p<0.001) and sperm density decreased (p<0.001) in the geriatric group. Statistically, oxidative stress parameters MDA, AOPP, T-SH levels increased (p<0.05) and CAT level decreased (p<0.05) in geriatric group. Histopathologically, degeneration, necrosis and irregular alignments were observed in the tubulus seminiferous contortus in the geriatric group. Hyperplasia and dilatation of the prostate gland were detected in the geriatric group. As a result of this study, it is thought that reproductive performance in geriatric male rats is very low, and the probability of reproduction is very difficult.
Anahtar Kelime: Geriatri Prostate Rat Sperm Testis.

Geriatrik (3 Yaşlı) Erkek Ratlarda Üreme Parametrelerinin Araştırılması

Öz:
Yaşlanmaya bağlı olarak pek çok sağlık sorunu görülmektedir. Bu sorunlardan biri de üreme sistemindeki problemlerdir. Üreme sistemi sorunlarına alt üriner sistem semptomları, prostat hastalıkları, düşük dölverimi, testis fonksiyon bozuklukları neden olur. Bu çalışmadaki amaç geriatrik (3 yaş) ve genç (3 aylık) sıçanların üreme parametrelerinin karşılaştırılması oldu. 3 yaşındaki bir rat ortalama 90-95 yaşındaki bir insana denk gelmektedir. Bu amaçla geriatrik (3 yaş) ve genç (3 aylık) ratlarda sperm analizi, testis ve prostat histopatolojisi, testiküler oksidatif stres parametreleri incelendi. Analiz sonuçlarında geriatric grupta sperm motilite oranının düştüğü (p<0.001), anormal sperm oranının arttığı (p<0.001), sperm yoğunluğunun azaldığı (p<0.001) belirlendi. İstatistiksel olarak geriatric grupta oksidatif stress parametrelerinin MDA, AOPP, T-SH seviyelerinin arttığı (p<0.05) ve CAT seviyesinin düştüğü (p<0.05) tespit edildi. Histopatolojik olarak geriatrik grupta tubulus seminiferous contortuslarda dejenerasyon, nekroz ve düzensiz dizilimler gözlendi. Geriatik grupta prostat bezinde hiperplazi ve dilatasyon tespit edildi. Bu çalışma verileri sonucunda geriatrik erkek ratlarda üreme performansının çok düşük olduğu ve üreme olasılığının çok zor olduğu düşünülmektedir.
Anahtar Kelime: Geriatri Prostat Rat Sperm Testis

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Koşal V, KELES O, kömüroğlu a, BAŞBUĞAN Y (2023). Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. , 174 - 179. 10.36483/vanvetj.1301038
Chicago Koşal Volkan,KELES OMER FARUK,kömüroğlu ahmet ufuk,BAŞBUĞAN Yıldıray Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. (2023): 174 - 179. 10.36483/vanvetj.1301038
MLA Koşal Volkan,KELES OMER FARUK,kömüroğlu ahmet ufuk,BAŞBUĞAN Yıldıray Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. , 2023, ss.174 - 179. 10.36483/vanvetj.1301038
AMA Koşal V,KELES O,kömüroğlu a,BAŞBUĞAN Y Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. . 2023; 174 - 179. 10.36483/vanvetj.1301038
Vancouver Koşal V,KELES O,kömüroğlu a,BAŞBUĞAN Y Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. . 2023; 174 - 179. 10.36483/vanvetj.1301038
IEEE Koşal V,KELES O,kömüroğlu a,BAŞBUĞAN Y "Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats." , ss.174 - 179, 2023. 10.36483/vanvetj.1301038
ISNAD Koşal, Volkan vd. "Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats". (2023), 174-179. https://doi.org/10.36483/vanvetj.1301038
APA Koşal V, KELES O, kömüroğlu a, BAŞBUĞAN Y (2023). Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. Van Veterinary Journal, 34(2), 174 - 179. 10.36483/vanvetj.1301038
Chicago Koşal Volkan,KELES OMER FARUK,kömüroğlu ahmet ufuk,BAŞBUĞAN Yıldıray Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. Van Veterinary Journal 34, no.2 (2023): 174 - 179. 10.36483/vanvetj.1301038
MLA Koşal Volkan,KELES OMER FARUK,kömüroğlu ahmet ufuk,BAŞBUĞAN Yıldıray Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. Van Veterinary Journal, vol.34, no.2, 2023, ss.174 - 179. 10.36483/vanvetj.1301038
AMA Koşal V,KELES O,kömüroğlu a,BAŞBUĞAN Y Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. Van Veterinary Journal. 2023; 34(2): 174 - 179. 10.36483/vanvetj.1301038
Vancouver Koşal V,KELES O,kömüroğlu a,BAŞBUĞAN Y Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats. Van Veterinary Journal. 2023; 34(2): 174 - 179. 10.36483/vanvetj.1301038
IEEE Koşal V,KELES O,kömüroğlu a,BAŞBUĞAN Y "Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats." Van Veterinary Journal, 34, ss.174 - 179, 2023. 10.36483/vanvetj.1301038
ISNAD Koşal, Volkan vd. "Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats". Van Veterinary Journal 34/2 (2023), 174-179. https://doi.org/10.36483/vanvetj.1301038
Sayfa Oluşturulma Tarihi
24-04-2024 9:6

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