Objective: This study aims to adapt the Patient-Nurse Trust Scale to Turkish and perform validity and reliability analyses. Methods: This study has been conducted as methodological. It was conducted between February 2021 and June 2021 in a training and research hospital in Istanbul, Turkey. The study was completed with 311 participants. Introductory Information Form, Patient-Nurse Trust Scale, and Trust in Nurses Scale were used for data collection. In addition to descriptive statistics, language validity, content validity, construct validity, criterionrelated validity, discrimination, internal consistency reliability, two-half test reliability, and item analysis methods were used to determine the scale’s psychometric properties. Results: As a result of factor analysis, it was determined that the scale showed a single factor structure, and explained 66.63% of the total variance. Item factor load values were found to vary between .74 and .88. The ratio of the chi-square value to the degrees of freedom (397.496/112) was found to be 3.549. It was found that RMSEA= .09, GFI= .86, IFI= .93, NFI= .91, CFI= .93, and RFI= .87. It was found that the correlations of all items varied between .71 and .87. The Chronbach’s alpha value for the whole scale was calculated as .97. As a result of parallel test analysis, it was determined that there was a significant positive correlation between both scales (r= .301; p= .000). Conclusion: The exploratory factor analysis and confirmatory factor analysis results of the Turkish version of the scale are acceptable, and their reliability indexes are high.