The trend towards online shopping is gaining momentum with the COVID-19 pandemic has affected the working conditions of cargo sector employees. This research was conducted by applying an online questionnaire to 469 union-member cargo sector employees to determine the changes in working conditions and their perceptions and attitudes towards the pandemic. The hypotheses established within the scope of the research questions were tested with the Chi- Square test. The survey results showed an increase in the working hours of the cargo sector employees (64%) and the number of people they served (83%). It has been determined that while hygiene, mask usage, and social distance measures were generally applied in workplaces, measures such as regulating working hours and keeping the number of employees at a minimum level still needed to be implemented. 70% of the respondents received OHS training during the pandemic. Gender, age groups, education level, job description in the workplace, and OHS education level do not make any difference in using PPE. It has been determined that the most important contributions of OHS training are practicing social distancing with colleagues, using the mask by hygiene rules, and learning the differences between masks. There is a higher rate of thought that the pandemic is carried out successfully in terms of OHS in those who receive OHS training. As a result, cargo sector employees stated that the pandemic adversely affected their workload, work stress, and health risks. However, they also thought these risks were eliminated with OHS measures.