TY  - JOUR
TI  - Adalimumab treatment in adult patients with refractory non-infectious uveitis
AB  - Purpose: To assess the efficacy of adalimumab treatment in patients with refractory non-infectious uveitis. Materials and Methods: A retrospective analysis was carried out on patients with chronic non-infectious uveitis treated with adalimumab for longer than 12 months. All patients had active intraocular inflammation and were nonresponsive to other immunosuppressive agents before initiating adalimumab treatment. Results: Twenty-one patients (39 eyes) were treated with adalimumab for a mean duration of 26.2 ± 13.2 months. Eleven patients (52.4%) remained relapse-free during the treatment. In only one patient (4.8%) adalimumab was switched to another drug due to insufficient response. Adalimumab treatment was discontinued in five patients (23.8%) after an attack-free period of at least 18 months. Conclusion: Adalimumab is an effective and well-tolerated therapeutic option for patients with refractory non-infectious uveitis, to achieve and maintain disease quiescence.
AU  - Esen, Ebru
AU  - Demircan, Nihal
AU  - Işık, Püren
AU  - Sizmaz, Selcuk
DO  - 10.17826/cumj.1224611
PY  - 2023
JO  - Cukurova Medical Journal
VL  - 48
IS  - 2
SN  - 2602-3032
SP  - 457
EP  - 462
DB  - TRDizin
UR  - http://search/yayin/detay/1197736
ER  -