Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits

SENEL, OYTUN OKAN; KAYA, Mahir; Pekcan, Zeynep; BUMIN, ALI; ŞEN, Yusuf; BOZTOK ÖZGERMEN, DEVA BAŞAK

Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits

Mahir KAYA, (Atatürk Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Erzurum, Türkiye)

Zeynep PEKCAN, (Kırıkkale Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Kırıkkale Türkiye)

Yusuf ŞEN, (Ankara Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Ankara, Türkiye)

DEVA BAŞAK BOZTOK ÖZGERMEN, (Ankara Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Ankara, Türkiye)

OYTUN OKAN ŞENEL, (Ankara Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Ankara, Türkiye)

Ali BUMİN (Ankara Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Ankara, Türkiye)

Kafkas Üniversitesi Veteriner Fakültesi Dergisi

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Yıl: 2011 Cilt: 17 Sayı: 5 Sayfa Aralığı: 713 - 719 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits

Öz:

Bu çalışma, kısa etkili anesteziklerin Doppler ultrasonografi ile saptanan hemodinamik fonksiyonlara etkilerini belirlemek amacıyla yürütüldü. Anestezi öncesi Yeni Zelanda tavşanlarının (n=24) sağ arteria carotis communis (CCA), aorta abdominalis (AA) ve sağ böbreğinden Doppler parametreleri [en yüksek sistolik kan akım hızı (psBFV), diyastol sonu kan akım hızı (edBFV), en düşük diyastolik kan akım hızı (mdBFV) ve rezistif indeks (RI)] elde edildi. Hayvanlar propofol (Grup P), %2.5 tiyopental sodyum (Grup T) ve ksilazin/ketamin HCl (Grup XK) ile anestezi altına alınarak, üç grup oluşturuldu. Anestezi sırasında aynı ölçümler tekrarlandı. Bazal değerler ile karşılaştırıldığında CCA’dan elde edilen psBFV Grup P’de yükseldi ve Grup T ve XK’daki değişim önemsizdi. Grup T ve XK’da AA’dan ölçülen psBFV bazal değerler ile kıyaslandığında azaldı. Sağ böbrekte, Grup P’nin psBFV ve Grup T’nin edBFV değerleri artarken, Grup T ve XK’da RI değeri azaldı. Sonuç olarak, propofol anestezisi bazal parametreler ile karşılaştırıldığında, CCA’deki RI, intrarenal RI ve AA’daki kan akımı hızlarını önemli ölçüde değiştirmediği tespit edildi. Veriler propofol anestezisinin tavşanlarda Doppler parametrelerini minimal düzeyde etkilediğini göstermektedir.

Anahtar Kelime: tavşan ketamin atardamarlar ultrasonografi ksilazin anestetikler böbrekler propofol aorta kan akışı tiyopental hemodinamik

Konular: Veterinerlik

Kısa-Etkili Anesteziklerin Tavşanlarda Hemodinamik Fonksiyonlara Etkilerinin Doppler Ultrasonografi ile Değerlendirilmesi

Öz:

This study was carried out to determine the effects of short-acting anaesthetics on haemodynamic function determined by Doppler ultrasonography. Prior to anaesthesia, Doppler parameters [peak systolic blood flow velocity (psBFV), end-diastolic blood flow velocity (edBFV), minimum diastolic blood flow velocity (mdBFV) and resistive index (RI)] were obtained from the right common carotid artery (CCA), abdominal aorta (AA) and right kidney in New Zealand rabbits (n=24). Animals were then divided into 3 groups to be anaesthetized with propofol (Group P), 2.5% thiopental sodium (Group T) and xylazine/ketamine HCl (Group XK). During anaesthesia the same Doppler measurements were made. Compared with baseline values, psBFV obtained from CCA increased in Group P (P<0.02) and insignificantly changed in Groups T and XK. psBFV measured from AA in Groups T and XK decreased as compared with baseline values. In the right kidney, psBFV in Group P and edBFV in Group T increased, whereas RI value in Groups T and XK decreased. In conclusion, comparing baseline values, propofol anaesthesia did not significantly alter RI measured from CCA and kidney and blood flow velocities measured from AA. The data suggest that propofol anaesthesia in rabbits results in minimal changes in Doppler parameters.

Anahtar Kelime: propofol aorta blood flow thiopental haemodynamics rabbits ketamine arteries ultrasonography xylazine anaesthetics kidneys

Konular: Veterinerlik

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KAYA M, Pekcan Z, ŞEN Y, BOZTOK ÖZGERMEN D, SENEL O, BUMIN A (2011). Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. , 713 - 719.
Chicago	KAYA Mahir,Pekcan Zeynep,ŞEN Yusuf,BOZTOK ÖZGERMEN DEVA BAŞAK,SENEL OYTUN OKAN,BUMIN ALI Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. (2011): 713 - 719.
MLA	KAYA Mahir,Pekcan Zeynep,ŞEN Yusuf,BOZTOK ÖZGERMEN DEVA BAŞAK,SENEL OYTUN OKAN,BUMIN ALI Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. , 2011, ss.713 - 719.
AMA	KAYA M,Pekcan Z,ŞEN Y,BOZTOK ÖZGERMEN D,SENEL O,BUMIN A Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. . 2011; 713 - 719.
Vancouver	KAYA M,Pekcan Z,ŞEN Y,BOZTOK ÖZGERMEN D,SENEL O,BUMIN A Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. . 2011; 713 - 719.
IEEE	KAYA M,Pekcan Z,ŞEN Y,BOZTOK ÖZGERMEN D,SENEL O,BUMIN A "Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits." , ss.713 - 719, 2011.
ISNAD	KAYA, Mahir vd. "Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits". (2011), 713-719.

APA	KAYA M, Pekcan Z, ŞEN Y, BOZTOK ÖZGERMEN D, SENEL O, BUMIN A (2011). Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 17(5), 713 - 719.
Chicago	KAYA Mahir,Pekcan Zeynep,ŞEN Yusuf,BOZTOK ÖZGERMEN DEVA BAŞAK,SENEL OYTUN OKAN,BUMIN ALI Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 17, no.5 (2011): 713 - 719.
MLA	KAYA Mahir,Pekcan Zeynep,ŞEN Yusuf,BOZTOK ÖZGERMEN DEVA BAŞAK,SENEL OYTUN OKAN,BUMIN ALI Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.17, no.5, 2011, ss.713 - 719.
AMA	KAYA M,Pekcan Z,ŞEN Y,BOZTOK ÖZGERMEN D,SENEL O,BUMIN A Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2011; 17(5): 713 - 719.
Vancouver	KAYA M,Pekcan Z,ŞEN Y,BOZTOK ÖZGERMEN D,SENEL O,BUMIN A Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2011; 17(5): 713 - 719.
IEEE	KAYA M,Pekcan Z,ŞEN Y,BOZTOK ÖZGERMEN D,SENEL O,BUMIN A "Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 17, ss.713 - 719, 2011.
ISNAD	KAYA, Mahir vd. "Effects of Short-Acting Anaesthetics on Haemodynamic Function as Determined by Doppler Ultrasonography in Rabbits". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 17/5 (2011), 713-719.