TY  - JOUR
TI  - Determination of Progesterone in Pharmaceutical Preparations by UV, First-order Derivative Spectrophotometry and Gas Chromatography
AB  - The determination of progesterone in pure and capsule form was accomplished in this work using new, simple and quick procedures by UV spectrophotometry, first-order derivative spectrophotometry and gas chromatography. To increase the sensitivity of the suggested methods, it was necessary to optimize the solvent system, the detection wavelength, and the chromatographic conditions. The linear regression equations for the UV spectrophotometry, first-order derivative spectrophotometry and gas chromatography were y=0.0536x+0.0002, y=0.1362x+0.0014, and y=1.8217x-1.239, respectively, as determined by the least square regression approach. Under the chosen experimental conditions, no interference was found. The suggested methods are extremely accurate and precise. When the suggested methods' findings were compared to those of two published reference methods, there was statistically no discernible difference. Therefore, the methods are applicable to the measurement of progesterone in pharmaceutical formulations.
AU  - Yılmaz, Bilal
AU  - Albayrak, Mevlut
AU  - KADIOGLU, Yucel
DO  - 10.17776/csj.1303270
PY  - 2023
JO  - Cumhuriyet Science Journal
VL  - 44
IS  - 3
SN  - 2587-2680
SP  - 456
EP  - 463
DB  - TRDizin
UR  - http://search/yayin/detay/1199263
ER  -