Aim: This study aims to evaluate the factors affecting the learning process of the physiotherapy and rehabilitation department students who continue their education with the hybrid education model, which is becoming increasingly widespread in the field of health education, from their perspectives. Methods: Students between 18 and 25 who continued their education in the Physiotherapy and Rehabilitation department with the hybrid education model and volunteered to participate in the study were included. The authors created a questionnaire consisting of 28 questions to evaluate the learning process factors. Results: Of 481 students, 388 (80.66%) women and 93 (19.33%) men, who continue their Physiotherapy and Rehabilitation education at 12 different universities, participated in the study. There are 127 (26.4%) students in the 1st grade, 60 (12.5%) in the 2nd grade, 132 (27.4%) in the 3rd grade, and 162 (33.7%) in the 4th grade. It has been determined that the students learn subjects they have never known before in face-to-face lessons more quickly and permanently. The frequent and abundant repetitions they made with videos create permanence in learning. In the face-to-face applied lessons, it was concluded that the timely feedback provided by the instructor had a facilitating effect on learning. It was determined that the social environments they created with their friends supported the learning process, and the absence of an obligation to attend the classes facilitated the learning process. In addition to the visual materials used during the lesson, it was determined that the lecturer’s camera, clear voice, and positive expression during the online lessons contributed positively to the student’s learning of the subject. Conclusion: As a result of this study, it was determined that the hybrid education model contains many factors that facilitate the student’s learning process and can be preferred in the field of health sciences provides positive contributions to the learning process. It is thought that is important to plan studies investigate the effectiveness of these strategies in the future, by adopting approaches that contribute positively to the learning process according to the students’ perspectives, developing the necessary strategies in current practices.