SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES

Göger, Gamze; Varnalı, Alişan; Ozek, Gulmira; Çevik, Esma; YAYLACI, Ömer Koray; Uma Koçum, Medine Münevver

doi:10.23902/trkjnat.1322140

SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES

Gamze GÖGER, (Afyonkarahisar Sağlık Bilimleri Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Afyonkarahisar, Türkiye)

Esma ÇEVİK, (Eczacılık Fakültesi, Trakya Üniversitesi, Edirne, 22030, Türkiye)

Alişan VARNALI, (Eczacılık Fakültesi, Trakya Üniversitesi, Edirne, 22030, Türkiye)

Ömer Koray YAYLACI, (Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Eskişehir, 26470, Türkiye)

Medine Münevver UMA, (Tekirdağ Namık Kemal Üniversitesi, Fen Bilimleri Enstitüsü, Biyoloji Anabilim Dalı, Tekirdağ, Türkiye)

Gülmira ÖZEK (Anadolu Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Eskişehir, 26470, Türkiye)

Trakya University Journal of Natural Sciences

4 0

Yıl: 2023 Cilt: 24 Sayı: 2 Sayfa Aralığı: 67 - 75 Metin Dili: İngilizce DOI: 10.23902/trkjnat.1322140 İndeks Tarihi: 23-10-2023

SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES

Öz:

The main aim of this study is antimicrobial screening of the n-hexane, ethyl acetate and aqueous extracts obtained from aerial parts of Achillea setacea Waldst. & Kit. and Achillea coarctata Poir. against the bacterial strains Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 14028 and the yeast Candida albicans ATCC 6633 by the microdilution method. In addition, the effect of the aqueous extract of A. coarctata combined with fluconazole againts C. albicans ATCC 6633, C. parapsilosis ATCC 22019, C. tropicalis ATCC 750 and C. glabrata ATCC 90030 was tested with the checkerboard method. The chemical components of the volatiles and fatty acid methyl esters were identified using the Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) techniques. The main components of the volatile oil were found to be 1,8-cineole (16.1%) and β-pinene (14.5%) for A. setacea and camphor (35.4%) and borneol (12.9%) for A. coarctata. The ethyl acetate extracts of A. setacea (MIC=156.25 µg/mL) and A. coarctata (MIC=312.5 µg/mL) were found more active against the tested Candida Berkh. species. The combination of aqueous extract of A. coarctata with fluconazole showed additive effect for the tested Candida species with FIC values within the range of 0.53-0.625 µg/mL.

Anahtar Kelime: Achillea setacea Achillea coarctata Phytochemical analyses GC/MS Checkerboard Additive effect

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Göger G, Çevik E, Varnalı A, YAYLACI Ö, Uma Koçum M, Ozek G (2023). SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. , 67 - 75. 10.23902/trkjnat.1322140
Chicago	Göger Gamze,Çevik Esma,Varnalı Alişan,YAYLACI Ömer Koray,Uma Koçum Medine Münevver,Ozek Gulmira SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. (2023): 67 - 75. 10.23902/trkjnat.1322140
MLA	Göger Gamze,Çevik Esma,Varnalı Alişan,YAYLACI Ömer Koray,Uma Koçum Medine Münevver,Ozek Gulmira SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. , 2023, ss.67 - 75. 10.23902/trkjnat.1322140
AMA	Göger G,Çevik E,Varnalı A,YAYLACI Ö,Uma Koçum M,Ozek G SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. . 2023; 67 - 75. 10.23902/trkjnat.1322140
Vancouver	Göger G,Çevik E,Varnalı A,YAYLACI Ö,Uma Koçum M,Ozek G SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. . 2023; 67 - 75. 10.23902/trkjnat.1322140
IEEE	Göger G,Çevik E,Varnalı A,YAYLACI Ö,Uma Koçum M,Ozek G "SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES." , ss.67 - 75, 2023. 10.23902/trkjnat.1322140
ISNAD	Göger, Gamze vd. "SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES". (2023), 67-75. https://doi.org/10.23902/trkjnat.1322140

APA	Göger G, Çevik E, Varnalı A, YAYLACI Ö, Uma Koçum M, Ozek G (2023). SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. Trakya University Journal of Natural Sciences, 24(2), 67 - 75. 10.23902/trkjnat.1322140
Chicago	Göger Gamze,Çevik Esma,Varnalı Alişan,YAYLACI Ömer Koray,Uma Koçum Medine Münevver,Ozek Gulmira SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. Trakya University Journal of Natural Sciences 24, no.2 (2023): 67 - 75. 10.23902/trkjnat.1322140
MLA	Göger Gamze,Çevik Esma,Varnalı Alişan,YAYLACI Ömer Koray,Uma Koçum Medine Münevver,Ozek Gulmira SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. Trakya University Journal of Natural Sciences, vol.24, no.2, 2023, ss.67 - 75. 10.23902/trkjnat.1322140
AMA	Göger G,Çevik E,Varnalı A,YAYLACI Ö,Uma Koçum M,Ozek G SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. Trakya University Journal of Natural Sciences. 2023; 24(2): 67 - 75. 10.23902/trkjnat.1322140
Vancouver	Göger G,Çevik E,Varnalı A,YAYLACI Ö,Uma Koçum M,Ozek G SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES. Trakya University Journal of Natural Sciences. 2023; 24(2): 67 - 75. 10.23902/trkjnat.1322140
IEEE	Göger G,Çevik E,Varnalı A,YAYLACI Ö,Uma Koçum M,Ozek G "SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES." Trakya University Journal of Natural Sciences, 24, ss.67 - 75, 2023. 10.23902/trkjnat.1322140
ISNAD	Göger, Gamze vd. "SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES". Trakya University Journal of Natural Sciences 24/2 (2023), 67-75. https://doi.org/10.23902/trkjnat.1322140