TY  - JOUR
TI  - Risk factors for post-acute sequelae of COVID-19 in hospitalized patients: An observational study based on a survey in a tertiary care center in Türkiye
AB  - Risk factors for post-acute sequelae of COVID-19 in hospitalized patients: An observational study based on a survey in a tertiary care center in Türkiye Introduction: Long COVID is a multisystem disease with various symptoms and risk factors. We aim to investigate the post-acute sequelae of COVID-19 and related risk factors in a tertiary care center. Materials and Methods: In this observational study, based on a survey of 1.977 COVID-19 patients hospitalized from April 2020 to January 2021, a retrospective assessment was carried out on 1.050 individuals who were reachable via telephone to determine their eligibility for meeting the inclusion criteria. Results: The data of 256 patients who reported at least one persistent symp- tom were analyzed. Long COVID prevalence was 24.3%. Among 256 patients (median age 52.8; 52.7% female; 56.63% had at least one comorbidity), dyspnea, fatigue, arthralgia-myalgia, cough, and back pain were the most common post-acute sequelae of COVID-19 (42.4%; 28.29%; 16.33%; 13.15% and 7.17%, respectively). The risk factors for the persistence of dysp- nea included having lung diseases such as chronic obstructive pulmonary disease, a history of intensive care support, the requirement for long-term oxygen therapy, and a history of cytokine storm (p= 0.024, p= 0.026, p< 0.001, p= 0.036, p= 0.005, respectively). The correlation between lung involvement with post-discharge cough (p= 0.041) and dizziness (p= 0.038) was significant. No correlation between the symptoms with the severity of acute infection, age, and gender was found. When a multivariate regression analysis was conducted on the most common long COVID-related symptoms, several independent risk factors were identified. These included having lung disease for dyspnea (OR 5.81, 95% CI 1.08-31.07, p= 0.04); length of hos- pital stay for myalgia (OR 1.034, 95% CI 1.004-1.065, p= 0.024); and pulmo- nary involvement of over 50% during COVID-19 infection for cough (OR 3.793, 95% CI 1.184-12.147, p= 0.025). Conclusion: COVID-19 survivors will require significant healthcare services due to their prolonged symptoms. We hope that our findings will guide the management of these patients in clinical settings towards best practices.
AU  - ÖZTÜRK ŞAHİN, Burcu
AU  - Yildiz, Yesim
AU  - TAŞDEMİR, MERT CAN
AU  - Demir, Şerife
AU  - ÇİFCİ, BEYZA
AU  - Kokturk, Nurdan
AU  - ULUKAVAK ÇIFTÇI, TANSU
AU  - YURDAKUL, AHMET SELIM
AU  - Yılmaz Demirci, Nilgün
AU  - AYDOĞDU, MÜGE
AU  - Dizbay, Murat
AU  - Oguzulgen, I.Kivilcim
DO  - 10.5578/tt.20239707
PY  - 2023
JO  - Tüberküloz ve Toraks
VL  - 71
IS  - 3
SN  - 0494-1373
SP  - 261
EP  - 272
DB  - TRDizin
UR  - http://search/yayin/detay/1203585
ER  -