Could SCUBE be used as a therapeutic target in rheumatoid arthritis?
Yıl: 2023 Cilt: 30 Sayı: 10 Sayfa Aralığı: 1196 - 1199 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2023.07.165 İndeks Tarihi: 30-10-2023
Could SCUBE be used as a therapeutic target in rheumatoid arthritis?
Öz: Aim: To investigate the levels of signal peptide-CUB-EGF domain-containing protein (SCUBE 1 and 3) in rheumatoid arthritis (RA). Materials and Methods: Twenty eight RA patients and 28 healthy volunteers were included in the study. SCUBE-1, SCUBE-3, Vascular Endothelial Growth Factor (VEGF), Matrix Metalloproteinase-9 (MMP-9), CD-40L, Interleukin-6 (IL-6) levels, which are important markers in angiogenesis, were measured twice, at baseline and after the treatment. Results: Compared to the healthy group, only MMP-9, one of the angiogenesis markers, was elevated in the patient group (p>0.05). After treatment, a significant decrease was observed in VEGF levels (p<0.05), while SCUBE-1, SCUBE-3, IL-6, CD-40 and MMP-9 levels remained at similar levels (p>0.05). Conclusion: In our study, RA patients responded to treatment with clinical improvements. Although there were differences in the levels of MMP and VEGF, there was no association with the disease in SCUBE.
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| APA | Çilesizoğlu Yavuz N, capkin e, Orem A, Menteşe A, us altay d (2023). Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. , 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| Chicago | Çilesizoğlu Yavuz Nurçe,capkin erhan,Orem Asım,Menteşe Ahmet,us altay diler Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. (2023): 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| MLA | Çilesizoğlu Yavuz Nurçe,capkin erhan,Orem Asım,Menteşe Ahmet,us altay diler Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. , 2023, ss.1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| AMA | Çilesizoğlu Yavuz N,capkin e,Orem A,Menteşe A,us altay d Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. . 2023; 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| Vancouver | Çilesizoğlu Yavuz N,capkin e,Orem A,Menteşe A,us altay d Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. . 2023; 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| IEEE | Çilesizoğlu Yavuz N,capkin e,Orem A,Menteşe A,us altay d "Could SCUBE be used as a therapeutic target in rheumatoid arthritis?." , ss.1196 - 1199, 2023. 10.5455/annalsmedres.2023.07.165 |
| ISNAD | Çilesizoğlu Yavuz, Nurçe vd. "Could SCUBE be used as a therapeutic target in rheumatoid arthritis?". (2023), 1196-1199. https://doi.org/10.5455/annalsmedres.2023.07.165 |
| APA | Çilesizoğlu Yavuz N, capkin e, Orem A, Menteşe A, us altay d (2023). Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. Annals of Medical Research, 30(10), 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| Chicago | Çilesizoğlu Yavuz Nurçe,capkin erhan,Orem Asım,Menteşe Ahmet,us altay diler Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. Annals of Medical Research 30, no.10 (2023): 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| MLA | Çilesizoğlu Yavuz Nurçe,capkin erhan,Orem Asım,Menteşe Ahmet,us altay diler Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. Annals of Medical Research, vol.30, no.10, 2023, ss.1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| AMA | Çilesizoğlu Yavuz N,capkin e,Orem A,Menteşe A,us altay d Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. Annals of Medical Research. 2023; 30(10): 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| Vancouver | Çilesizoğlu Yavuz N,capkin e,Orem A,Menteşe A,us altay d Could SCUBE be used as a therapeutic target in rheumatoid arthritis?. Annals of Medical Research. 2023; 30(10): 1196 - 1199. 10.5455/annalsmedres.2023.07.165 |
| IEEE | Çilesizoğlu Yavuz N,capkin e,Orem A,Menteşe A,us altay d "Could SCUBE be used as a therapeutic target in rheumatoid arthritis?." Annals of Medical Research, 30, ss.1196 - 1199, 2023. 10.5455/annalsmedres.2023.07.165 |
| ISNAD | Çilesizoğlu Yavuz, Nurçe vd. "Could SCUBE be used as a therapeutic target in rheumatoid arthritis?". Annals of Medical Research 30/10 (2023), 1196-1199. https://doi.org/10.5455/annalsmedres.2023.07.165 |
