Aim: The present study aimed to determine if there is any relationship between childhood traumas, emotion regulation, depression, and anxiety with psoriasis severity; it also attempted to find out whether these factors affect the development of psoriasis. Materials and Methods: This study enrolled 100 patients with psoriasis aged 18-65 years and 100 healthy volunteers free of any form of psychiatric treatment, active psychiatric symptoms, and dermatological diseases. Sociodemographic Data Form, Childhood Traumas Scale (CTS), Difficulties in Emotion Regulation Scale (DERS), Hamilton Anxiety Scale (HAM-A), and Hamilton Depression Scale (HAM-D) were filled by the study subjects. Results: The patients and controls were compared with respect to HAM-D, HAM-A, CTS, and DERS scales. The patients had higher HAM-D, HAM-A, CTS Physical abuse, CTS Physical neglect CTS Emotional neglect, CTS Sexual abuse, CTS Total, DERS Clarity, DERS Impulse scores than the controls (Table 2) (p<0.001, p:0.011, p:0.021, p:0.005, p<0.001, p:0.045, p<0.001, p<0.001, respectively). Conclusion: Psoriasis should be treated in collaboration of dermatology, psychiatry, immunology, rheumatology, and even medical pharmacology departments.