The effect of plasmapheresis therapy on management of patients with snakebite

Aim: The aim of the study was to evaluate the effectiveness of plasmapheresis therapy in patients with snakebite who were admitted to intensive care unit in the setting of tertiary referral hospital. Materials and Methods: The retrospective study involved 114 adult patients with snakebite who were admitted to a referral hospital’s intensive care unit between January 2012 and December 2022. The patients were divided into four groups according to the treatments. Group AV performed antivenom (Group AV) alone. Group PP performed plasmapheresis alone. Group AV+PP performed antivenom and plasmapheresis. Group GST performed only general supportive therapy. Results: Fifty two of 114 were included in Group GST, 31 in Group AV, 18 in Group PP and 13 in Group AV+PP. APACHE score, SOFA score, GCS, stage of the bite, length of stay in the intensive care unit, acute kidney injury, and hematological disorders were higher while the platelet count at admission was lower in Group PP and Group AV+PP compared to Group AV and Group GST (p< 0.05). Conclusion: Antivenom and plasmapheresis are not alternatives to each other, antivenom should be performed to patients according to the severity of the bite, and plasmapheresis should be performed without delay in those with severe hematological effects.

Anahtar Kelime: Snakebite Anti-venom Plasmapheresis Intensive care unit

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	BİCAKCİOGLU M, KALKAN S, DOĞAN Z, togal t, Yucel N, DEMİRCAN S, DUZENCI D, korkmaz dişli z, aydogan m, OZER A (2023). The effect of plasmapheresis therapy on management of patients with snakebite. , 1144 - 1148. 10.5455/annalsmedres.2023.08.223
Chicago	BİCAKCİOGLU Murat,KALKAN SERKAN,DOĞAN Zafer,togal turkan,Yucel Neslihan,DEMİRCAN SELÇUK,DUZENCI DECCANE,korkmaz dişli zeliha,aydogan mustafa said,OZER Ayse Belin The effect of plasmapheresis therapy on management of patients with snakebite. (2023): 1144 - 1148. 10.5455/annalsmedres.2023.08.223
MLA	BİCAKCİOGLU Murat,KALKAN SERKAN,DOĞAN Zafer,togal turkan,Yucel Neslihan,DEMİRCAN SELÇUK,DUZENCI DECCANE,korkmaz dişli zeliha,aydogan mustafa said,OZER Ayse Belin The effect of plasmapheresis therapy on management of patients with snakebite. , 2023, ss.1144 - 1148. 10.5455/annalsmedres.2023.08.223
AMA	BİCAKCİOGLU M,KALKAN S,DOĞAN Z,togal t,Yucel N,DEMİRCAN S,DUZENCI D,korkmaz dişli z,aydogan m,OZER A The effect of plasmapheresis therapy on management of patients with snakebite. . 2023; 1144 - 1148. 10.5455/annalsmedres.2023.08.223
Vancouver	BİCAKCİOGLU M,KALKAN S,DOĞAN Z,togal t,Yucel N,DEMİRCAN S,DUZENCI D,korkmaz dişli z,aydogan m,OZER A The effect of plasmapheresis therapy on management of patients with snakebite. . 2023; 1144 - 1148. 10.5455/annalsmedres.2023.08.223
IEEE	BİCAKCİOGLU M,KALKAN S,DOĞAN Z,togal t,Yucel N,DEMİRCAN S,DUZENCI D,korkmaz dişli z,aydogan m,OZER A "The effect of plasmapheresis therapy on management of patients with snakebite." , ss.1144 - 1148, 2023. 10.5455/annalsmedres.2023.08.223
ISNAD	BİCAKCİOGLU, Murat vd. "The effect of plasmapheresis therapy on management of patients with snakebite". (2023), 1144-1148. https://doi.org/10.5455/annalsmedres.2023.08.223

APA	BİCAKCİOGLU M, KALKAN S, DOĞAN Z, togal t, Yucel N, DEMİRCAN S, DUZENCI D, korkmaz dişli z, aydogan m, OZER A (2023). The effect of plasmapheresis therapy on management of patients with snakebite. Annals of Medical Research, 30(9), 1144 - 1148. 10.5455/annalsmedres.2023.08.223
Chicago	BİCAKCİOGLU Murat,KALKAN SERKAN,DOĞAN Zafer,togal turkan,Yucel Neslihan,DEMİRCAN SELÇUK,DUZENCI DECCANE,korkmaz dişli zeliha,aydogan mustafa said,OZER Ayse Belin The effect of plasmapheresis therapy on management of patients with snakebite. Annals of Medical Research 30, no.9 (2023): 1144 - 1148. 10.5455/annalsmedres.2023.08.223
MLA	BİCAKCİOGLU Murat,KALKAN SERKAN,DOĞAN Zafer,togal turkan,Yucel Neslihan,DEMİRCAN SELÇUK,DUZENCI DECCANE,korkmaz dişli zeliha,aydogan mustafa said,OZER Ayse Belin The effect of plasmapheresis therapy on management of patients with snakebite. Annals of Medical Research, vol.30, no.9, 2023, ss.1144 - 1148. 10.5455/annalsmedres.2023.08.223
AMA	BİCAKCİOGLU M,KALKAN S,DOĞAN Z,togal t,Yucel N,DEMİRCAN S,DUZENCI D,korkmaz dişli z,aydogan m,OZER A The effect of plasmapheresis therapy on management of patients with snakebite. Annals of Medical Research. 2023; 30(9): 1144 - 1148. 10.5455/annalsmedres.2023.08.223
Vancouver	BİCAKCİOGLU M,KALKAN S,DOĞAN Z,togal t,Yucel N,DEMİRCAN S,DUZENCI D,korkmaz dişli z,aydogan m,OZER A The effect of plasmapheresis therapy on management of patients with snakebite. Annals of Medical Research. 2023; 30(9): 1144 - 1148. 10.5455/annalsmedres.2023.08.223
IEEE	BİCAKCİOGLU M,KALKAN S,DOĞAN Z,togal t,Yucel N,DEMİRCAN S,DUZENCI D,korkmaz dişli z,aydogan m,OZER A "The effect of plasmapheresis therapy on management of patients with snakebite." Annals of Medical Research, 30, ss.1144 - 1148, 2023. 10.5455/annalsmedres.2023.08.223
ISNAD	BİCAKCİOGLU, Murat vd. "The effect of plasmapheresis therapy on management of patients with snakebite". Annals of Medical Research 30/9 (2023), 1144-1148. https://doi.org/10.5455/annalsmedres.2023.08.223