In this study, medical terms in the manuscript called Risâle-i Tıbb, which is registered with the number 06 Mil YzA 671 in the Ankara National Library Manuscripts Collection, will be discussed. In both Ottoman medicine and Islamic medicine, human health was given great importance and protection from diseases was considered important. As in the example of Eşref bin Muhammed, one of the Ottoman physicians, health was equated with happiness and it was emphasized that a person could not be healthy without a healthy body. Because the other elements that make up the essence of man can be healthy only if the body is healthy. In this understanding, which is believed to be the prevention of diseases, the main thing is given importance to the measures that people should take in order to meet their needs such as "food, sleep, clothing" which are a part of their daily life. In this traditional understanding, when natural treatment is not possible, the priority has been to prefer "curricular" cures with simple content. Then, it was tried to benefit from "combined" drugs with combined content. Risale-i Tıbb, which is the subject of this study, is a medical book that includes "simple drugs" in classical medicine. There is no information about the writing date of the work. The examples in the work, which shows the characteristics of Old Oghuz Turkish, and the harmony of flatness and roundness suggest that it may have been written in the Classical Ottoman period. It is possible to say that Risâle-i Tıbb has a rich content in terms of Turkish terms. The Arabic, Persian and Greek terms found in the old medical tradition are also included in the work. In the work, Turkish words are used intensively in the names of "organ, disease and animal". In plant names, the ratio of Arabic and Persian words is higher. The Risâle-i Tıbb, which includes medical terms at the time it was written, consists of 11 leaves. The aim of the work is to contribute to both medical studies and the Turkish language.