A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis

Türkmen, Şeyma; sozeri, betul; Taşar, Sevinç; güzel, MERYEM; Sönmez, Hafize Emine; Çakan, Mustafa

doi:10.24953/turkjped.2022.935

A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis

Şeyma TÜRKMEN, (Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Çocuk Romatoloji Kliniği, İstanbul, Türkiye)

Sevinç TAŞAR, (Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Çocuk Radyolojisi Kliniği, İstanbul, Türkiye)

Meryem GÜZEL, (Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Çocuk Romatoloji Kliniği, İstanbul, Türkiye)

Hafize Emine SÖNMEZ, (Kocaeli Üniversitesi, Tıp Fakültesi, Çocuk Romatoloji Anabilim Dalı, Kocaeli, Türkiye)

Mustafa ÇAKAN, (Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Çocuk Romatoloji Kliniği, İstanbul, Türkiye)

Betül SÖZERİ (Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Çocuk Romatoloji Kliniği, İstanbul, Türkiye)

Turkish Journal of Pediatrics

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Yıl: 2023 Cilt: 65 Sayı: 5 Sayfa Aralığı: 868 - 873 Metin Dili: İngilizce DOI: 10.24953/turkjped.2022.935 İndeks Tarihi: 16-11-2023

A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis

Öz:

Background. IgA vasculitis (IgAV) is a multisystemic small vessel vasculitis and is the most common vasculitis in childhood. The characteristic findings of IgAV are palpable purpuric rash, abdominal pain, arthralgia or arthritis, and hematuria. Ischemic complications are very rare in IgAV. Thrombotic complications can be observed after a COVID-19 infection. Also in the presence of familial Mediterranean fever, IgAV may have an atypical or more severe course. Case. We present a case of IgAV complicated with renal infarction and intestinal ischemia. There was no recent or distant history of COVID-19 in the patient or family members, but the patient’s COVID-19 antibody was positive. In addition, MEFV gene analysis of the patient showed homozygous M694V mutation. The patient did not respond to enoxaparin, pulse methylprednisolone, intravenous immunoglobulin (IVIG), iloprost, and cyclophosphamide treatments. She was successfully treated with six sessions of plasmapheresis. Conclusions. Plasmapheresis seems to be an effective treatment option in IgAV-related ischemic findings that do not respond to intensive immunosuppressive therapy.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	Türkmen Ş, Taşar S, güzel M, Sönmez H, Çakan M, sozeri b (2023). A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. , 868 - 873. 10.24953/turkjped.2022.935
Chicago	Türkmen Şeyma,Taşar Sevinç,güzel MERYEM,Sönmez Hafize Emine,Çakan Mustafa,sozeri betul A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. (2023): 868 - 873. 10.24953/turkjped.2022.935
MLA	Türkmen Şeyma,Taşar Sevinç,güzel MERYEM,Sönmez Hafize Emine,Çakan Mustafa,sozeri betul A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. , 2023, ss.868 - 873. 10.24953/turkjped.2022.935
AMA	Türkmen Ş,Taşar S,güzel M,Sönmez H,Çakan M,sozeri b A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. . 2023; 868 - 873. 10.24953/turkjped.2022.935
Vancouver	Türkmen Ş,Taşar S,güzel M,Sönmez H,Çakan M,sozeri b A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. . 2023; 868 - 873. 10.24953/turkjped.2022.935
IEEE	Türkmen Ş,Taşar S,güzel M,Sönmez H,Çakan M,sozeri b "A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis." , ss.868 - 873, 2023. 10.24953/turkjped.2022.935
ISNAD	Türkmen, Şeyma vd. "A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis". (2023), 868-873. https://doi.org/10.24953/turkjped.2022.935

APA	Türkmen Ş, Taşar S, güzel M, Sönmez H, Çakan M, sozeri b (2023). A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. Turkish Journal of Pediatrics, 65(5), 868 - 873. 10.24953/turkjped.2022.935
Chicago	Türkmen Şeyma,Taşar Sevinç,güzel MERYEM,Sönmez Hafize Emine,Çakan Mustafa,sozeri betul A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. Turkish Journal of Pediatrics 65, no.5 (2023): 868 - 873. 10.24953/turkjped.2022.935
MLA	Türkmen Şeyma,Taşar Sevinç,güzel MERYEM,Sönmez Hafize Emine,Çakan Mustafa,sozeri betul A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. Turkish Journal of Pediatrics, vol.65, no.5, 2023, ss.868 - 873. 10.24953/turkjped.2022.935
AMA	Türkmen Ş,Taşar S,güzel M,Sönmez H,Çakan M,sozeri b A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. Turkish Journal of Pediatrics. 2023; 65(5): 868 - 873. 10.24953/turkjped.2022.935
Vancouver	Türkmen Ş,Taşar S,güzel M,Sönmez H,Çakan M,sozeri b A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis. Turkish Journal of Pediatrics. 2023; 65(5): 868 - 873. 10.24953/turkjped.2022.935
IEEE	Türkmen Ş,Taşar S,güzel M,Sönmez H,Çakan M,sozeri b "A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis." Turkish Journal of Pediatrics, 65, ss.868 - 873, 2023. 10.24953/turkjped.2022.935
ISNAD	Türkmen, Şeyma vd. "A rare complication of IgA vasculitis: renal and intestinal ischemia successfully treated with plasmapheresis". Turkish Journal of Pediatrics 65/5 (2023), 868-873. https://doi.org/10.24953/turkjped.2022.935