TY  - JOUR
TI  - Comparatively sonophotochemical and photochemical studies of phthalocyanines with cationic substituents on nonperipheral positions
AB  - The term sonophotodynamic therapy (SPDT) refers to a combination of sonodynamic therapy (SDT) and photodynamic therapy (PDT), in which the efficacy of the treatment is boosted by utilizing the proper amount of a sensitizer that is responsive to both light and ultrasound. Although it has been proven in photophysicochemical studies that SPDT enhances singlet oxygen production, related studies in the literature are very limited. Considering this situation, this study aims to investigate the efficacy of synthesized phthalocyanines in terms of PDT and SPDT. The singlet oxygen quantum values calculated as 0.13 for 5, 0.44 for 6, and 0.61 for 7 in photochemical (PDT) application increased to 0.18, 0.86, and 0.92, respectively, with sonophotochemical (SPDT) application. According to the results, singlet oxygen production was more efficient with SPDT. This work will add to the body of knowledge on employing the SPDT approach to increase singlet oxygen generation.
AU  - Ozcesmeci, Mukaddes
AU  - Can, Ceren
AU  - ERDOGMUS, ALI
AU  - Hamuryudan, Esin
DO  - 10.55730/1300-0527.3602
PY  - 2023
JO  - Turkish Journal of Chemistry
VL  - 47
IS  - 5
SN  - 1300-0527
SP  - 1160
EP  - 1168
DB  - TRDizin
UR  - http://search/yayin/detay/1208484
ER  -